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The past, present, and future of chemical biology in auxin research

Bert De Rybel UGent, Dominique Audenaert UGent, Tom Beeckman UGent and Stefan Kepinski (2009) ACS CHEMICAL BIOLOGY. 4(12). p.987-998
abstract
Research into the plant hormone auxin has always been tightly linked with the use of small molecules, In fact, most of the known players in auxin signaling and transport in the model plant Arabidopsis thaliana were Identified by screening for resistance to auxin analogues. The use of high-throughput screening technologies has since yielded many novel molecules, opening the way for the identification of new target proteins to further elucidate known pathways. Here, we give an overview of well-established and novel molecules used in auxin research and highlight the current status and future perspectives of chemical biology approaches to auxin biology.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
BRASSINOSTEROID-BIOSYNTHESIS, ROOT GRAVITROPISM, PROTEIN, GENE FAMILY-MEMBERS, ARABIDOPSIS-THALIANA, FUNCTIONAL GENOMIC ANALYSIS, Auxin, Aux/IAA, F-box protein, Indole-3-acetic acid (IAA), Auxin probe, TIR1/AFB, INHIBITORS, EFFLUX, TERFESTATIN-A, ACID
journal title
ACS CHEMICAL BIOLOGY
ACS Chem. Biol.
volume
4
issue
12
pages
12 pages
Web of Science type
Article
Web of Science id
000272845900004
JCR category
BIOCHEMISTRY & MOLECULAR BIOLOGY
JCR impact factor
5.108 (2009)
JCR rank
52/281 (2009)
JCR quartile
1 (2009)
ISSN
1554-8929
DOI
10.1021/cb9001624
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
851002
handle
http://hdl.handle.net/1854/LU-851002
date created
2010-02-03 16:44:35
date last changed
2010-07-01 10:10:03
@article{851002,
  abstract     = {Research into the plant hormone auxin has always been tightly linked with the use of small molecules, In fact, most of the known players in auxin signaling and transport in the model plant Arabidopsis thaliana were Identified by screening for resistance to auxin analogues. The use of high-throughput screening technologies has since yielded many novel molecules, opening the way for the identification of new target proteins to further elucidate known pathways. Here, we give an overview of well-established and novel molecules used in auxin research and highlight the current status and future perspectives of chemical biology approaches to auxin biology.},
  author       = {De Rybel, Bert and Audenaert, Dominique and Beeckman, Tom and Kepinski, Stefan},
  issn         = {1554-8929},
  journal      = {ACS CHEMICAL BIOLOGY},
  keyword      = {BRASSINOSTEROID-BIOSYNTHESIS,ROOT GRAVITROPISM,PROTEIN,GENE FAMILY-MEMBERS,ARABIDOPSIS-THALIANA,FUNCTIONAL GENOMIC ANALYSIS,Auxin,Aux/IAA,F-box protein,Indole-3-acetic acid (IAA),Auxin probe,TIR1/AFB,INHIBITORS,EFFLUX,TERFESTATIN-A,ACID},
  language     = {eng},
  number       = {12},
  pages        = {987--998},
  title        = {The past, present, and future of chemical biology in auxin research},
  url          = {http://dx.doi.org/10.1021/cb9001624},
  volume       = {4},
  year         = {2009},
}

Chicago
De Rybel, Bert, Dominique Audenaert, Tom Beeckman, and Stefan Kepinski. 2009. “The Past, Present, and Future of Chemical Biology in Auxin Research.” Acs Chemical Biology 4 (12): 987–998.
APA
De Rybel, B., Audenaert, D., Beeckman, T., & Kepinski, S. (2009). The past, present, and future of chemical biology in auxin research. ACS CHEMICAL BIOLOGY, 4(12), 987–998.
Vancouver
1.
De Rybel B, Audenaert D, Beeckman T, Kepinski S. The past, present, and future of chemical biology in auxin research. ACS CHEMICAL BIOLOGY. 2009;4(12):987–98.
MLA
De Rybel, Bert, Dominique Audenaert, Tom Beeckman, et al. “The Past, Present, and Future of Chemical Biology in Auxin Research.” ACS CHEMICAL BIOLOGY 4.12 (2009): 987–998. Print.