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Carbon dioxide production during cardiopulmonary bypass : pathophysiology, measure and clinical relevance

(2017) PERFUSION-UK. 32(1). p.4-12
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Abstract
Carbon dioxide production during cardiopulmonary bypass derives from both the aerobic metabolism and the buffering of lactic acid produced by tissues under anaerobic conditions. Therefore, carbon dioxide removal monitoring is an important measure of the adequacy of perfusion and oxygen delivery. However, routine monitoring of carbon dioxide removal is not widely applied. The present article reviews the main physiological and pathophysiological sources of carbon dioxide, the available techniques to assess carbon dioxide production and removal and the clinically relevant applications of carbon dioxide-related variables as markers of the adequacy of perfusion during cardiopulmonary bypass.
Keywords
cardiopulmonary bypass, carbon dioxide, capnography, blood lactates, oxygen delivery, ACUTE KIDNEY INJURY, VENOUS OXYGEN-SATURATION, BLOOD LACTATE LEVELS, OPEN-HEART-SURGERY, ANAEROBIC METABOLISM, PCO2 DIFFERENCE, CARDIAC-SURGERY, CO2 PRODUCTION, LACTIC-ACID, ARTERIAL

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Citation

Please use this url to cite or link to this publication:

Chicago
Ranucci, Marco, Giovanni Carboni, Mauro Cotza, and Filip De Somer. 2017. “Carbon Dioxide Production During Cardiopulmonary Bypass : Pathophysiology, Measure and Clinical Relevance.” Perfusion-uk 32 (1): 4–12.
APA
Ranucci, M., Carboni, G., Cotza, M., & De Somer, F. (2017). Carbon dioxide production during cardiopulmonary bypass : pathophysiology, measure and clinical relevance. PERFUSION-UK, 32(1), 4–12.
Vancouver
1.
Ranucci M, Carboni G, Cotza M, De Somer F. Carbon dioxide production during cardiopulmonary bypass : pathophysiology, measure and clinical relevance. PERFUSION-UK. 2017;32(1):4–12.
MLA
Ranucci, Marco et al. “Carbon Dioxide Production During Cardiopulmonary Bypass : Pathophysiology, Measure and Clinical Relevance.” PERFUSION-UK 32.1 (2017): 4–12. Print.
@article{8509661,
  abstract     = {Carbon dioxide production during cardiopulmonary bypass derives from both the aerobic metabolism and the buffering of lactic acid produced by tissues under anaerobic conditions. Therefore, carbon dioxide removal monitoring is an important measure of the adequacy of perfusion and oxygen delivery. However, routine monitoring of carbon dioxide removal is not widely applied. The present article reviews the main physiological and pathophysiological sources of carbon dioxide, the available techniques to assess carbon dioxide production and removal and the clinically relevant applications of carbon dioxide-related variables as markers of the adequacy of perfusion during cardiopulmonary bypass.},
  author       = {Ranucci, Marco and Carboni, Giovanni and Cotza, Mauro and De Somer, Filip},
  issn         = {0267-6591},
  journal      = {PERFUSION-UK},
  keywords     = {cardiopulmonary bypass,carbon dioxide,capnography,blood lactates,oxygen delivery,ACUTE KIDNEY INJURY,VENOUS OXYGEN-SATURATION,BLOOD LACTATE LEVELS,OPEN-HEART-SURGERY,ANAEROBIC METABOLISM,PCO2 DIFFERENCE,CARDIAC-SURGERY,CO2 PRODUCTION,LACTIC-ACID,ARTERIAL},
  language     = {eng},
  number       = {1},
  pages        = {4--12},
  title        = {Carbon dioxide production during cardiopulmonary bypass : pathophysiology, measure and clinical relevance},
  url          = {http://dx.doi.org/10.1177/0267659116659919},
  volume       = {32},
  year         = {2017},
}

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