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Assessing the performance of ultrafast vector flow imaging in the neonatal heart via multiphysics modeling and In vitro experiments

Joris Van Cauwenberge, Lasse Lovstakken, Solveig Fadnes, Alfonso Rodriguez-Morales, Jan Vierendeels UGent, Patrick Segers UGent and Abigaïl Swillens (2016) IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL. 63(11). p.1772-1785
abstract
Ultrafast vector flow imaging would benefit newborn patients with congenital heart disorders, but still requires thorough validation before translation to clinical practice. This paper investigates 2-D speckle tracking (ST) of intraventricular blood flow in neonates when transmitting diverging waves at ultrafast frame rate. Computational and in vitro studies enabled us to quantify the performance and identify artifacts related to the flow and the imaging sequence. First, synthetic ultrasound images of a neonate's left ventricular flow pattern were obtained with the ultrasound simulator Field II by propagating point scatterers according to 3-D intraventricular flow fields obtained with computational fluid dynamics (CFD). Noncompounded diverging waves (opening angle of 60 degrees) were transmitted at a pulse repetition frequency of 9 kHz. ST of the B-mode data provided 2-D flow estimates at 180 Hz, which were compared with the CFD flow field. We demonstrated that the diastolic inflow jet showed a strong bias in the lateral velocity estimates at the edges of the jet, as confirmed by additional in vitro tests on a jet flow phantom. Furthermore, ST performance was highly dependent on the cardiac phase with low flows (< 5 cm/s), high spatial flow gradients, and out-of-plane flow as deteriorating factors. Despite the observed artifacts, a good overall performance of 2-D ST was obtained with a median magnitude underestimation and angular deviation of, respectively, 28% and 13.5 degrees during systole and 16% and 10.5 degrees during diastole.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
keyword
FLUID-STRUCTURE INTERACTION, SPECKLE TRACKING, BLOOD-FLOW, NORMAL, VALUES, PARTITIONED SIMULATION, VELOCITY ESTIMATION, PLANE-WAVE, ULTRASOUND, DOPPLER, ECHOCARDIOGRAPHY, Blood flow measurement, medical imaging, medical signal and image, processing
journal title
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
IEEE Trans. Ultrason. Ferroelectr. Freq. Control
volume
63
issue
11
pages
14 pages
publisher
Ieee-inst Electrical Electronics Engineers Inc
place of publication
Piscataway
Web of Science type
Article
Web of Science id
000387987300007
JCR category
ACOUSTICS
JCR impact factor
2.743 (2016)
JCR rank
4/31 (2016)
JCR quartile
1 (2016)
ISSN
0885-3010
1525-8955
DOI
10.1109/TUFFC.2016.2596804
language
English
UGent publication?
yes
classification
A1
copyright statement
I don't know the status of the copyright for this publication
id
8508295
handle
http://hdl.handle.net/1854/LU-8508295
date created
2017-02-08 14:10:09
date last changed
2017-06-28 09:21:26
@article{8508295,
  abstract     = {Ultrafast vector flow imaging would benefit newborn patients with congenital heart disorders, but still requires thorough validation before translation to clinical practice. This paper investigates 2-D speckle tracking (ST) of intraventricular blood flow in neonates when transmitting diverging waves at ultrafast frame rate. Computational and in vitro studies enabled us to quantify the performance and identify artifacts related to the flow and the imaging sequence. First, synthetic ultrasound images of a neonate's left ventricular flow pattern were obtained with the ultrasound simulator Field II by propagating point scatterers according to 3-D intraventricular flow fields obtained with computational fluid dynamics (CFD). Noncompounded diverging waves (opening angle of 60 degrees) were transmitted at a pulse repetition frequency of 9 kHz. ST of the B-mode data provided 2-D flow estimates at 180 Hz, which were compared with the CFD flow field. We demonstrated that the diastolic inflow jet showed a strong bias in the lateral velocity estimates at the edges of the jet, as confirmed by additional in vitro tests on a jet flow phantom. Furthermore, ST performance was highly dependent on the cardiac phase with low flows ({\textlangle} 5 cm/s), high spatial flow gradients, and out-of-plane flow as deteriorating factors. Despite the observed artifacts, a good overall performance of 2-D ST was obtained with a median magnitude underestimation and angular deviation of, respectively, 28\% and 13.5 degrees during systole and 16\% and 10.5 degrees during diastole.},
  author       = {Van Cauwenberge, Joris and Lovstakken, Lasse and Fadnes, Solveig and Rodriguez-Morales, Alfonso and Vierendeels, Jan and Segers, Patrick and Swillens, Abiga{\"i}l},
  issn         = {0885-3010},
  journal      = {IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL},
  keyword      = {FLUID-STRUCTURE INTERACTION,SPECKLE TRACKING,BLOOD-FLOW,NORMAL,VALUES,PARTITIONED SIMULATION,VELOCITY ESTIMATION,PLANE-WAVE,ULTRASOUND,DOPPLER,ECHOCARDIOGRAPHY,Blood flow measurement,medical imaging,medical signal and image,processing},
  language     = {eng},
  number       = {11},
  pages        = {1772--1785},
  publisher    = {Ieee-inst Electrical Electronics Engineers Inc},
  title        = {Assessing the performance of ultrafast vector flow imaging in the neonatal heart via multiphysics modeling and In vitro experiments},
  url          = {http://dx.doi.org/10.1109/TUFFC.2016.2596804},
  volume       = {63},
  year         = {2016},
}

Chicago
Van Cauwenberge, Joris, Lasse Lovstakken, Solveig Fadnes, Alfonso Rodriguez-Morales, Jan Vierendeels, Patrick Segers, and Abigaïl Swillens. 2016. “Assessing the Performance of Ultrafast Vector Flow Imaging in the Neonatal Heart via Multiphysics Modeling and In Vitro Experiments.” Ieee Transactions on Ultrasonics Ferroelectrics and Frequency Control 63 (11): 1772–1785.
APA
Van Cauwenberge, J., Lovstakken, L., Fadnes, S., Rodriguez-Morales, A., Vierendeels, J., Segers, P., & Swillens, A. (2016). Assessing the performance of ultrafast vector flow imaging in the neonatal heart via multiphysics modeling and In vitro experiments. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 63(11), 1772–1785.
Vancouver
1.
Van Cauwenberge J, Lovstakken L, Fadnes S, Rodriguez-Morales A, Vierendeels J, Segers P, et al. Assessing the performance of ultrafast vector flow imaging in the neonatal heart via multiphysics modeling and In vitro experiments. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL. Piscataway: Ieee-inst Electrical Electronics Engineers Inc; 2016;63(11):1772–85.
MLA
Van Cauwenberge, Joris, Lasse Lovstakken, Solveig Fadnes, et al. “Assessing the Performance of Ultrafast Vector Flow Imaging in the Neonatal Heart via Multiphysics Modeling and In Vitro Experiments.” IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL 63.11 (2016): 1772–1785. Print.