Ghent University Academic Bibliography

Advanced

The unique peptidome : taxon-specific tryptic peptides as biomarkers for targeted metaproteomics

Bart Mesuere UGent, Felix Van der Jeugt UGent, Bart Devreese UGent, Peter Vandamme UGent and Peter Dawyndt UGent (2016) PROTEOMICS. 16(17). p.2313-2318
abstract
The Unique Peptide Finder (http://unipept.ugent.be/peptidefinder) is an interactive web application to quickly hunt for tryptic peptides that are unique to a particular species, genus or any other taxon. Biodiversity within the target taxon is represented by a set of proteomes selected from a monthly updated list of complete and non-redundant UniProt proteomes, supplemented with proprietary proteomes loaded into persistent local browser storage. The software computes and visualizes pan and core peptidomes as unions and intersections of tryptic peptides occurring in the selected proteomes. In addition, it also computes and displays unique peptidomes as the set of all tryptic peptides that occur in all selected proteomes but not in any UniProt record not assigned to the target taxon. As a result, the unique peptides can serve as robust biomarkers for the target taxon, e.g. in targeted metaproteomics studies. Computations are extremely fast since they are underpinned by the Unipept database, the Lowest Common Ancestor algorithm implemented in Unipept and modern web technologies that facilitate in-browser data storage and parallel processing.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
biomarkers, data visualization, software, targeted metaproteomics, tryptic peptides, ACINETOBACTER-BAUMANNII, PROTEOMICS, INFORMATION, PREDICTION, GENOMICS, DATABASE
journal title
PROTEOMICS
Proteomics
volume
16
issue
17
pages
2313 - 2318
Web of Science type
Article
Web of Science id
000383611400002
JCR category
BIOCHEMICAL RESEARCH METHODS
JCR impact factor
4.041 (2016)
JCR rank
15/77 (2016)
JCR quartile
1 (2016)
ISSN
1615-9853
DOI
10.1002/pmic.201600023
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
8507600
handle
http://hdl.handle.net/1854/LU-8507600
date created
2017-02-05 15:15:39
date last changed
2017-06-13 09:25:15
@article{8507600,
  abstract     = {The Unique Peptide Finder (http://unipept.ugent.be/peptidefinder) is an interactive web application to quickly hunt for tryptic peptides that are unique to a particular species, genus or any other taxon. Biodiversity within the target taxon is represented by a set of proteomes selected from a monthly updated list of complete and non-redundant UniProt proteomes, supplemented with proprietary proteomes loaded into persistent local browser storage. The software computes and visualizes pan and core peptidomes as unions and intersections of tryptic peptides occurring in the selected proteomes. In addition, it also computes and displays unique peptidomes as the set of all tryptic peptides that occur in all selected proteomes but not in any UniProt record not assigned to the target taxon. As a result, the unique peptides can serve as robust biomarkers for the target taxon, e.g. in targeted metaproteomics studies. Computations are extremely fast since they are underpinned by the Unipept database, the Lowest Common Ancestor algorithm implemented in Unipept and modern web technologies that facilitate in-browser data storage and parallel processing.},
  author       = {Mesuere, Bart and Van der Jeugt, Felix and Devreese, Bart and Vandamme, Peter and Dawyndt, Peter},
  issn         = {1615-9853},
  journal      = {PROTEOMICS},
  keyword      = {biomarkers,data visualization,software,targeted metaproteomics,tryptic peptides,ACINETOBACTER-BAUMANNII,PROTEOMICS,INFORMATION,PREDICTION,GENOMICS,DATABASE},
  language     = {eng},
  number       = {17},
  pages        = {2313--2318},
  title        = {The unique peptidome : taxon-specific tryptic peptides as biomarkers for targeted metaproteomics},
  url          = {http://dx.doi.org/10.1002/pmic.201600023},
  volume       = {16},
  year         = {2016},
}

Chicago
Mesuere, Bart, Felix Van der Jeugt, Bart Devreese, Peter Vandamme, and Peter Dawyndt. 2016. “The Unique Peptidome : Taxon-specific Tryptic Peptides as Biomarkers for Targeted Metaproteomics.” Proteomics 16 (17): 2313–2318.
APA
Mesuere, B., Van der Jeugt, F., Devreese, B., Vandamme, P., & Dawyndt, P. (2016). The unique peptidome : taxon-specific tryptic peptides as biomarkers for targeted metaproteomics. PROTEOMICS, 16(17), 2313–2318.
Vancouver
1.
Mesuere B, Van der Jeugt F, Devreese B, Vandamme P, Dawyndt P. The unique peptidome : taxon-specific tryptic peptides as biomarkers for targeted metaproteomics. PROTEOMICS. 2016;16(17):2313–8.
MLA
Mesuere, Bart, Felix Van der Jeugt, Bart Devreese, et al. “The Unique Peptidome : Taxon-specific Tryptic Peptides as Biomarkers for Targeted Metaproteomics.” PROTEOMICS 16.17 (2016): 2313–2318. Print.