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Fractional carbon dioxide laser of recent surgical scars in the head and neck region : a split-scar, evaluator-blinded study

Sarah Buelens (UGent) , Anne-Sophie Van Hove, Katia Ongenae (UGent) , Hilde Lapeere (UGent) , Wouter Huvenne (UGent) , Hubert Vermeersch (UGent) , Evelien Verhaeghe (UGent) and Barbara Boone (UGent)
(2017) DERMATOLOGIC SURGERY. 43(suppl. 1). p.S75-S84
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Organization
Abstract
BACKGROUND: Postoperative scarring is a common cause of patient dissatisfaction. Several strategies have been developed to improve its clinical aspects. OBJECTIVE: To assess efficacy and safety of the 10,600 nm ablative fractional carbon dioxide (CO2) laser in the treatment of recent surgical scars in the head and neck region. METHODS AND MATERIALS: A prospective, randomized, single-blind intrapatient controlled study was conducted on 9 postoperative scars in the head and neck region. On half of the scar, 3 treatment sessions were performed. Physician/Patient Global Assessment (PhGA/PGA) and Patient and Observer Scar Assessment Scales (POSAS) were used to evaluate treatment efficacy. Safety was evaluated by registration of pain and adverse events. RESULTS: No statistically significant differences were noted in terms of PhGA or POSAS (observer). Patient Global Assessment (p = 0.058) and POSAS (patient) (p = 0.091) showed a trend toward better improvement of the treated half. Itch score (p = 0.046) and global end evaluation (patient) (p = 0.026) demonstrated a statistically significant difference in favor of the treated part. Adverse events were minor, and no long-term side effects were noted. CONCLUSION: The use of CO2 fractional laser is safe and is associated with high patient satisfaction. However, objective measurements could not confirm its efficacy in the treatment of recent surgical scars.
Keywords
EARLY POSTOPERATIVE TREATMENT, ADVERSE EVENTS, APPRAISAL

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MLA
Buelens, Sarah et al. “Fractional Carbon Dioxide Laser of Recent Surgical Scars in the Head and Neck Region : a Split-scar, Evaluator-blinded Study.” DERMATOLOGIC SURGERY 43.suppl. 1 (2017): S75–S84. Print.
APA
Buelens, S., Van Hove, A.-S., Ongenae, K., Lapeere, H., Huvenne, W., Vermeersch, H., Verhaeghe, E., et al. (2017). Fractional carbon dioxide laser of recent surgical scars in the head and neck region : a split-scar, evaluator-blinded study. DERMATOLOGIC SURGERY, 43(suppl. 1), S75–S84.
Chicago author-date
Buelens, Sarah, Anne-Sophie Van Hove, Katia Ongenae, Hilde Lapeere, Wouter Huvenne, Hubert Vermeersch, Evelien Verhaeghe, and Barbara Boone. 2017. “Fractional Carbon Dioxide Laser of Recent Surgical Scars in the Head and Neck Region : a Split-scar, Evaluator-blinded Study.” Dermatologic Surgery 43 (suppl. 1): S75–S84.
Chicago author-date (all authors)
Buelens, Sarah, Anne-Sophie Van Hove, Katia Ongenae, Hilde Lapeere, Wouter Huvenne, Hubert Vermeersch, Evelien Verhaeghe, and Barbara Boone. 2017. “Fractional Carbon Dioxide Laser of Recent Surgical Scars in the Head and Neck Region : a Split-scar, Evaluator-blinded Study.” Dermatologic Surgery 43 (suppl. 1): S75–S84.
Vancouver
1.
Buelens S, Van Hove A-S, Ongenae K, Lapeere H, Huvenne W, Vermeersch H, et al. Fractional carbon dioxide laser of recent surgical scars in the head and neck region : a split-scar, evaluator-blinded study. DERMATOLOGIC SURGERY. 2017;43(suppl. 1):S75–S84.
IEEE
[1]
S. Buelens et al., “Fractional carbon dioxide laser of recent surgical scars in the head and neck region : a split-scar, evaluator-blinded study,” DERMATOLOGIC SURGERY, vol. 43, no. suppl. 1, pp. S75–S84, 2017.
@article{8507081,
  abstract     = {BACKGROUND: Postoperative scarring is a common cause of patient dissatisfaction. Several strategies have been developed to improve its clinical aspects.
OBJECTIVE: To assess efficacy and safety of the 10,600 nm ablative fractional carbon dioxide (CO2) laser in the treatment of recent surgical scars in the head and neck region. 
METHODS AND MATERIALS: A prospective, randomized, single-blind intrapatient controlled study was conducted on 9 postoperative scars in the head and neck region. On half of the scar, 3 treatment sessions were performed. Physician/Patient Global Assessment (PhGA/PGA) and Patient and Observer Scar Assessment Scales (POSAS) were used to evaluate treatment efficacy. Safety was evaluated by registration of pain and adverse events. 
RESULTS: No statistically significant differences were noted in terms of PhGA or POSAS (observer). Patient Global Assessment (p = 0.058) and POSAS (patient) (p = 0.091) showed a trend toward better improvement of the treated half. Itch score (p = 0.046) and global end evaluation (patient) (p = 0.026) demonstrated a statistically significant difference in favor of the treated part. Adverse events were minor, and no long-term side effects were noted. 
CONCLUSION: The use of CO2 fractional laser is safe and is associated with high patient satisfaction. However, objective measurements could not confirm its efficacy in the treatment of recent surgical scars.},
  author       = {Buelens, Sarah and Van Hove, Anne-Sophie and Ongenae, Katia and Lapeere, Hilde and Huvenne, Wouter and Vermeersch, Hubert and Verhaeghe, Evelien and Boone, Barbara},
  issn         = {1076-0512},
  journal      = {DERMATOLOGIC SURGERY},
  keywords     = {EARLY POSTOPERATIVE TREATMENT,ADVERSE EVENTS,APPRAISAL},
  language     = {eng},
  number       = {suppl. 1},
  pages        = {S75--S84},
  title        = {Fractional carbon dioxide laser of recent surgical scars in the head and neck region : a split-scar, evaluator-blinded study},
  url          = {http://dx.doi.org/10.1097/dss.0000000000000963},
  volume       = {43},
  year         = {2017},
}

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