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Persistent aggregates in apheresis platelet concentrates are commonly collected from donors with a history of aggregate donation

(2016) VOX SANGUINIS. 111(4). p.431-433
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Abstract
Platelet apheresis sometimes causes persistent aggregates (PA). This study (n = 211) shows that changing the apheresis settings to reach fixed product volumes instead of yields does not influence PA incidence, even though PA products on average contain more platelets than controls. Furthermore, logistic regression was used to model if PA can be predicted on the basis of certain predonation parameters. PA donation history was the only parameter retained, proving a strong determinant of predictability [AUC = 0.735 (SE = 0.022)]. Consequently, donations from a donor with previous PA history are 7.8 times more likely to contain PA than from a donor without preceding history.
Keywords
apheresis - donation, Blood collection, Platelet concentrates

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Citation

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Chicago
Feys, Hendrik, H Pottel, J Coene, G Vandewalle, Philippe Vandekerckhove, and Veerle Compernolle. 2016. “Persistent Aggregates in Apheresis Platelet Concentrates Are Commonly Collected from Donors with a History of Aggregate Donation.” Vox Sanguinis 111 (4): 431–433.
APA
Feys, Hendrik, Pottel, H., Coene, J., Vandewalle, G., Vandekerckhove, P., & Compernolle, V. (2016). Persistent aggregates in apheresis platelet concentrates are commonly collected from donors with a history of aggregate donation. VOX SANGUINIS, 111(4), 431–433.
Vancouver
1.
Feys H, Pottel H, Coene J, Vandewalle G, Vandekerckhove P, Compernolle V. Persistent aggregates in apheresis platelet concentrates are commonly collected from donors with a history of aggregate donation. VOX SANGUINIS. 2016;111(4):431–3.
MLA
Feys, Hendrik, H Pottel, J Coene, et al. “Persistent Aggregates in Apheresis Platelet Concentrates Are Commonly Collected from Donors with a History of Aggregate Donation.” VOX SANGUINIS 111.4 (2016): 431–433. Print.
@article{8507034,
  abstract     = {Platelet apheresis sometimes causes persistent aggregates (PA). This study (n = 211) shows that changing the apheresis settings to reach fixed product volumes instead of yields does not influence PA incidence, even though PA products on average contain more platelets than controls. Furthermore, logistic regression was used to model if PA can be predicted on the basis of certain predonation parameters. PA donation history was the only parameter retained, proving a strong determinant of predictability [AUC = 0.735 (SE = 0.022)]. Consequently, donations from a donor with previous PA history are 7.8 times more likely to contain PA than from a donor without preceding history.},
  author       = {Feys, Hendrik and Pottel, H and Coene, J and Vandewalle, G and Vandekerckhove, Philippe and Compernolle, Veerle},
  issn         = {0042-9007},
  journal      = {VOX SANGUINIS},
  language     = {eng},
  number       = {4},
  pages        = {431--433},
  title        = {Persistent aggregates in apheresis platelet concentrates are commonly collected from donors with a history of aggregate donation},
  url          = {http://dx.doi.org/10.1111/vox.12437},
  volume       = {111},
  year         = {2016},
}

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