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Viruses and bacteria in Th2-biased allergic airway disease

F Lan, Nan Zhang (UGent) , Elien Gevaert (UGent) , L Zhang and Claus Bachert (UGent)
(2016) ALLERGY. 71(10). p.1381-1392
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Abstract
Allergic airway diseases are typically characterized by a type 2-biased inflammation. Multiple distinct viruses and bacteria have been detected in the airways. Recently, it has been confirmed that the microbiome of allergic individuals differs from that of healthy subjects, showing a close relationship with the type 2 response in allergic airway disease. In this review, we summarize the recent findings on the prevalence of viruses and bacteria in type 2-biased airway diseases and on the mechanisms employed by viruses and bacteria in propagating type 2 responses. The understanding of the microbial composition and postinfectious immune programming is critical for the reconstruction of the normal microflora and immune status in allergic airway diseases.
Keywords
allergy rhinitis, asthma, chronic rhinosinusitis, microbiome, Th2 response, STAPHYLOCOCCUS-AUREUS COLONIZATION, RESPIRATORY EPITHELIAL-CELLS, THYMIC STROMAL LYMPHOPOIETIN, CHRONIC RHINOSINUSITIS, IMMUNE-RESPONSES, CHILDHOOD ASTHMA, NASAL POLYPOSIS, TH2 CYTOKINES, BIRTH-COHORT, 1ST YEAR

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Citation

Please use this url to cite or link to this publication:

Chicago
Lan, F, Nan Zhang, Elien Gevaert, L Zhang, and Claus Bachert. 2016. “Viruses and Bacteria in Th2-biased Allergic Airway Disease.” Allergy 71 (10): 1381–1392.
APA
Lan, F, Zhang, N., Gevaert, E., Zhang, L., & Bachert, C. (2016). Viruses and bacteria in Th2-biased allergic airway disease. ALLERGY, 71(10), 1381–1392.
Vancouver
1.
Lan F, Zhang N, Gevaert E, Zhang L, Bachert C. Viruses and bacteria in Th2-biased allergic airway disease. ALLERGY. 2016;71(10):1381–92.
MLA
Lan, F, Nan Zhang, Elien Gevaert, et al. “Viruses and Bacteria in Th2-biased Allergic Airway Disease.” ALLERGY 71.10 (2016): 1381–1392. Print.
@article{8506459,
  abstract     = {Allergic airway diseases are typically characterized by a type 2-biased inflammation. Multiple distinct viruses and bacteria have been detected in the airways. Recently, it has been confirmed that the microbiome of allergic individuals differs from that of healthy subjects, showing a close relationship with the type 2 response in allergic airway disease. In this review, we summarize the recent findings on the prevalence of viruses and bacteria in type 2-biased airway diseases and on the mechanisms employed by viruses and bacteria in propagating type 2 responses. The understanding of the microbial composition and postinfectious immune programming is critical for the reconstruction of the normal microflora and immune status in allergic airway diseases.},
  author       = {Lan, F and Zhang, Nan and Gevaert, Elien and Zhang, L and Bachert, Claus},
  issn         = {0105-4538},
  journal      = {ALLERGY},
  keyword      = {allergy rhinitis,asthma,chronic rhinosinusitis,microbiome,Th2 response,STAPHYLOCOCCUS-AUREUS COLONIZATION,RESPIRATORY EPITHELIAL-CELLS,THYMIC STROMAL LYMPHOPOIETIN,CHRONIC RHINOSINUSITIS,IMMUNE-RESPONSES,CHILDHOOD ASTHMA,NASAL POLYPOSIS,TH2 CYTOKINES,BIRTH-COHORT,1ST YEAR},
  language     = {eng},
  number       = {10},
  pages        = {1381--1392},
  title        = {Viruses and bacteria in Th2-biased allergic airway disease},
  url          = {http://dx.doi.org/10.1111/all.12934},
  volume       = {71},
  year         = {2016},
}

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