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Leaf growth response to mild drought : natural variation in Arabidopsis sheds light on trait architecture

Pieter Clauw, Frederik Coppens UGent, Arthur Korte, Dorota Herman, Bram Slabbinck, Stijn Dhondt UGent, Twiggy Van Daele UGent, Liesbeth De Milde UGent, Mattias Vermeersch UGent, Katrien Maleux, et al. (2016) PLANT CELL. 28(10). p.2417-2434
abstract
Plant growth and crop yield are negatively affected by a reduction in water availability. However, a clear understanding of how growth is regulated under nonlethal drought conditions is lacking. Recent advances in genomics, phenomics, and transcriptomics allow in-depth analysis of natural variation. In this study, we conducted a detailed screening of leaf growth responses to mild drought in a worldwide collection of Arabidopsis thaliana accessions. The genetic architecture of the growth responses upon mild drought was investigated by subjecting the different leaf growth phenotypes to genome-wide association mapping and by characterizing the transcriptome of young developing leaves. Although no major effect locus was found to be associated with growth in mild drought, the transcriptome analysis delivered further insight into the natural variation of transcriptional responses to mild drought in a specific tissue. Coexpression analysis indicated the presence of gene clusters that co-vary over different genetic backgrounds, among others a cluster of genes with important regulatory functions in the growth response to osmotic stress. It was found that the occurrence of a mild drought stress response in leaves can be inferred with high accuracy across accessions based on the expression profile of 283 genes. A genome-wide association study on the expression data revealed that trans regulation seems to be more important than cis regulation in the transcriptional response to environmental perturbations.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
GENOME-WIDE ASSOCIATION, WATER-LIMITING CONDITIONS, GENE-EXPRESSION, PLANT-GROWTH, THALIANA ACCESSIONS, TRANSPOSABLE ELEMENTS, TRANSCRIPTION, FACTORS, REGULATORY VARIATION, STRESS RESPONSES, OSMOTIC-STRESS
journal title
PLANT CELL
Plant Cell
volume
28
issue
10
pages
2417 - 2434
Web of Science type
Article
Web of Science id
000390135400010
JCR category
PLANT SCIENCES
JCR impact factor
8.688 (2016)
JCR rank
6/211 (2016)
JCR quartile
1 (2016)
ISSN
1040-4651
1532-298X
DOI
10.1105/tpc.16.00483
language
English
UGent publication?
yes
classification
A1
copyright statement
I have retained and own the full copyright for this publication
id
8503027
handle
http://hdl.handle.net/1854/LU-8503027
date created
2017-01-19 15:15:06
date last changed
2017-08-01 09:43:12
@article{8503027,
  abstract     = {Plant growth and crop yield are negatively affected by a reduction in water availability. However, a clear understanding of how growth is regulated under nonlethal drought conditions is lacking. Recent advances in genomics, phenomics, and transcriptomics allow in-depth analysis of natural variation. In this study, we conducted a detailed screening of leaf growth responses to mild drought in a worldwide collection of Arabidopsis thaliana accessions. The genetic architecture of the growth responses upon mild drought was investigated by subjecting the different leaf growth phenotypes to genome-wide association mapping and by characterizing the transcriptome of young developing leaves. Although no major effect locus was found to be associated with growth in mild drought, the transcriptome analysis delivered further insight into the natural variation of transcriptional responses to mild drought in a specific tissue. Coexpression analysis indicated the presence of gene clusters that co-vary over different genetic backgrounds, among others a cluster of genes with important regulatory functions in the growth response to osmotic stress. It was found that the occurrence of a mild drought stress response in leaves can be inferred with high accuracy across accessions based on the expression profile of 283 genes. A genome-wide association study on the expression data revealed that trans regulation seems to be more important than cis regulation in the transcriptional response to environmental perturbations.},
  author       = {Clauw, Pieter and Coppens, Frederik and Korte, Arthur and Herman, Dorota and Slabbinck, Bram and Dhondt, Stijn and Van Daele, Twiggy and De Milde, Liesbeth and Vermeersch, Mattias and Maleux, Katrien and Maere, Steven and Gonzalez Sanchez, Nathalie and Inz{\'e}, Dirk},
  issn         = {1040-4651},
  journal      = {PLANT CELL},
  keyword      = {GENOME-WIDE ASSOCIATION,WATER-LIMITING CONDITIONS,GENE-EXPRESSION,PLANT-GROWTH,THALIANA ACCESSIONS,TRANSPOSABLE ELEMENTS,TRANSCRIPTION,FACTORS,REGULATORY VARIATION,STRESS RESPONSES,OSMOTIC-STRESS},
  language     = {eng},
  number       = {10},
  pages        = {2417--2434},
  title        = {Leaf growth response to mild drought : natural variation in Arabidopsis sheds light on trait architecture},
  url          = {http://dx.doi.org/10.1105/tpc.16.00483},
  volume       = {28},
  year         = {2016},
}

Chicago
Clauw, Pieter, Frederik Coppens, Arthur Korte, Dorota Herman, Bram Slabbinck, Stijn Dhondt, Twiggy Van Daele, et al. 2016. “Leaf Growth Response to Mild Drought : Natural Variation in Arabidopsis Sheds Light on Trait Architecture.” Plant Cell 28 (10): 2417–2434.
APA
Clauw, P., Coppens, F., Korte, A., Herman, D., Slabbinck, B., Dhondt, S., Van Daele, T., et al. (2016). Leaf growth response to mild drought : natural variation in Arabidopsis sheds light on trait architecture. PLANT CELL, 28(10), 2417–2434.
Vancouver
1.
Clauw P, Coppens F, Korte A, Herman D, Slabbinck B, Dhondt S, et al. Leaf growth response to mild drought : natural variation in Arabidopsis sheds light on trait architecture. PLANT CELL. 2016;28(10):2417–34.
MLA
Clauw, Pieter, Frederik Coppens, Arthur Korte, et al. “Leaf Growth Response to Mild Drought : Natural Variation in Arabidopsis Sheds Light on Trait Architecture.” PLANT CELL 28.10 (2016): 2417–2434. Print.