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The reservoir pressure concept: the 3-element windkessel model revisited?: application to the Asklepios population study

SEBASTIAN VERMEERSCH UGent, Ernst Rietzschel UGent, MARC DE BUYZERE UGent, Lucas Van Bortel UGent, Thierry Gillebert UGent, Pascal Verdonck UGent and Patrick Segers UGent (2009) JOURNAL OF ENGINEERING MATHEMATICS. 64(4). p.417-428
abstract
Traditionally the arterial system is either modeled as a lumped-parameter windkessel or a wave system. Recently, a hybrid model has been proposed in which the arterial system is considered to be a reservoir allowing for superimposed wave phenomena. This approach was applied to non-invasively obtained carotid pressure waveforms from 2019 subjects from the Asklepios population to investigate the contribution of reservoir pressure (PP (res,WS)) to carotid pulse pressure (PP (car)) with age and gender. Additionally, reservoir pressures were compared to the reservoir pressure (PP (res,WK)) obtained from a 3-element windkessel model. PP (res,WK) and PP (res,WS) were determined by applying a 3-element windkessel model and the wave separation model to scaled carotid artery tonometry readings. The evolution of PP (car), PP (res,WK) and PP (res,WS) was examined for men and women after stratification into age quartiles. PP (car) increased with age regardless of sex, but was more pronounced in women, with significant (P < 0.001) age-gender interaction. PP (res) increases with age (P < 0.001), regardless of the model used for its determination, but more significantly for women. In men it only increases markedly in the oldest age group. Overall, the reservoir pressure concept showed large similarities to the classical 3-element windkessel model, especially in subjects characterized by a high reflection magnitude and high "windkesselness" of their arterial system. When applied to the Asklepios population, both models show the increase of pulse pressure with age to be largely due to increasing reservoir pressures.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
Arterial system, Arterial stiffness, Hemodynamics, Modeling, Pulse pressure, Wave reflection, SYSTEMIC ARTERIAL TREE, NONINVASIVE ASSESSMENT, PULSE PRESSURE, BLOOD-PRESSURE, HEALTHY, WAVES, TONOMETRY, VELOCITY, DESIGN, FLOW
journal title
JOURNAL OF ENGINEERING MATHEMATICS
J. Eng. Math.
volume
64
issue
4
pages
417 - 428
Web of Science type
Article
Web of Science id
000267295600009
JCR category
ENGINEERING, MULTIDISCIPLINARY
JCR impact factor
0.691 (2009)
JCR rank
41/79 (2009)
JCR quartile
3 (2009)
ISSN
0022-0833
DOI
10.1007/s10665-009-9286-y
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
846332
handle
http://hdl.handle.net/1854/LU-846332
date created
2010-01-29 16:32:50
date last changed
2010-02-04 16:59:26
@article{846332,
  abstract     = {Traditionally the arterial system is either modeled as a lumped-parameter windkessel or a wave system. Recently, a hybrid model has been proposed in which the arterial system is considered to be a reservoir allowing for superimposed wave phenomena. This approach was applied to non-invasively obtained carotid pressure waveforms from 2019 subjects from the Asklepios population to investigate the contribution of reservoir pressure (PP (res,WS)) to carotid pulse pressure (PP (car)) with age and gender. Additionally, reservoir pressures were compared to the reservoir pressure (PP (res,WK)) obtained from a 3-element windkessel model. PP (res,WK) and PP (res,WS) were determined by applying a 3-element windkessel model and the wave separation model to scaled carotid artery tonometry readings. The evolution of PP (car), PP (res,WK) and PP (res,WS) was examined for men and women after stratification into age quartiles. PP (car) increased with age regardless of sex, but was more pronounced in women, with significant (P {\textlangle} 0.001) age-gender interaction. PP (res) increases with age (P {\textlangle}  0.001), regardless of the model used for its determination, but more significantly for women. In men it only increases markedly in the oldest age group. Overall, the reservoir pressure concept showed large similarities to the classical 3-element windkessel model, especially in subjects characterized by a high reflection magnitude and high {\textacutedbl}windkesselness{\textacutedbl} of their arterial system. When applied to the Asklepios population, both models show the increase of pulse pressure with age to be largely due to increasing reservoir pressures.},
  author       = {VERMEERSCH, SEBASTIAN and Rietzschel, Ernst and DE BUYZERE, MARC and Van Bortel, Lucas and Gillebert, Thierry and Verdonck, Pascal and Segers, Patrick},
  issn         = {0022-0833},
  journal      = {JOURNAL OF ENGINEERING MATHEMATICS},
  keyword      = {Arterial system,Arterial stiffness,Hemodynamics,Modeling,Pulse pressure,Wave reflection,SYSTEMIC ARTERIAL TREE,NONINVASIVE ASSESSMENT,PULSE PRESSURE,BLOOD-PRESSURE,HEALTHY,WAVES,TONOMETRY,VELOCITY,DESIGN,FLOW},
  language     = {eng},
  number       = {4},
  pages        = {417--428},
  title        = {The reservoir pressure concept: the 3-element windkessel model revisited?: application to the Asklepios population study},
  url          = {http://dx.doi.org/10.1007/s10665-009-9286-y},
  volume       = {64},
  year         = {2009},
}

Chicago
VERMEERSCH, SEBASTIAN, Ernst Rietzschel, Marc De Buyzere, Lucas Van Bortel, Thierry Gillebert, Pascal Verdonck, and Patrick Segers. 2009. “The Reservoir Pressure Concept: The 3-element Windkessel Model Revisited?: Application to the Asklepios Population Study.” Journal of Engineering Mathematics 64 (4): 417–428.
APA
VERMEERSCH, SEBASTIAN, Rietzschel, E., De Buyzere, M., Van Bortel, L., Gillebert, T., Verdonck, P., & Segers, P. (2009). The reservoir pressure concept: the 3-element windkessel model revisited?: application to the Asklepios population study. JOURNAL OF ENGINEERING MATHEMATICS, 64(4), 417–428.
Vancouver
1.
VERMEERSCH S, Rietzschel E, De Buyzere M, Van Bortel L, Gillebert T, Verdonck P, et al. The reservoir pressure concept: the 3-element windkessel model revisited?: application to the Asklepios population study. JOURNAL OF ENGINEERING MATHEMATICS. 2009;64(4):417–28.
MLA
VERMEERSCH, SEBASTIAN, Ernst Rietzschel, Marc De Buyzere, et al. “The Reservoir Pressure Concept: The 3-element Windkessel Model Revisited?: Application to the Asklepios Population Study.” JOURNAL OF ENGINEERING MATHEMATICS 64.4 (2009): 417–428. Print.