@article{837718,
  abstract     = {Previous studies in healthy volunteers reported a possible impact of high frequency repetitive transcranial magnetic stimulation (HF-rTMS) on stress hormones, like cortisol. In this sham-controlled, "single blind'', crossover study, we examined whether HF-rTMS had an effect on the hypothalamic-pituitary-adrenal (HPA) axis, by analysing salivary cortisol levels. Two studies were conducted. First, HF-rTMS on the left dorsolateral prefrontal cortex (DLPFC) was performed in 28 young healthy female volunteers. Second, in a comparable, but different group of 26 healthy females, HF-rTMS was performed on the right DLPFC. Salivary cortisol levels were assessed before, immediately after and 30 min after real and sham HF-rTMS. We found no support for the hypothesis that one single session of HF-rTMS on the left or the right DLPFC has an immediate or delayed impact on the HPA-axis, as measured by salivary cortisol. Although we controlled for several methodological problems in HF-rTMS research, the hypothesis that one single session of HF-rTMS on the left or on the right DLPFC can influence the HPA-axis in healthy volunteers was not supported.},
  author       = {Baeken, Chris and De Raedt, Rudi and Leyman, Lemke and Schiettecatte, Johan and Poppe, Kris and Kaufman, Leon and Haes, Margot and Vanderhasselt, Marie-Anne and Anckaert, Ellen and D'Haenen, Hugo},
  issn         = {1562-2975},
  journal      = {WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY},
  keywords     = {salivary cortisol,healthy volunteers,TMS,CHALLENGE,ASSAYS,GENDER,HPA AXIS RESPONSES,HORMONE-LEVELS,TRANSCRANIAL MAGNETIC STIMULATION,STRESS,DEPRESSION,HF-rTMS},
  language     = {eng},
  number       = {5},
  pages        = {586--590},
  title        = {The impact of one session of HF-rTMS on salivary cortisol in healthy female subjects},
  url          = {http://dx.doi.org/10.3109/15622970701560351},
  volume       = {10},
  year         = {2009},
}

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