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An oxygen consuming phantom for simulating oxygen perfusion in tissue using 19F MRI oximetry

Steven Baete UGent and Yves De Deene UGent (2009) Proceedings of the International Society for Magnetic Resonance in Medicine. 17. p.832-832
abstract
Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used to map oxygen concentrations in hypoxic tissue. However, validation of pO2-measurements in vivo is difficult. In this study, an oxygen consuming phantom simulating oxygen perfusion in tissue is presented. The phantom consists of a hemodialysis filter of which the outer compartment is filled with a gel containing viable yeast cells. pO2-images reveal oxygen consumption by the yeast cells after injection of a bolus of oxygen rich hexafluorobenzene in the fibers of the hemodialysis filter. The developed phantom can be used for validation of Fluor-19 MRI oximetry.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
in
Proceedings of the International Society for Magnetic Resonance in Medicine
volume
17
pages
832 - 832
conference name
ISMRM 17th Scientific Meeting and Exhibition (ISMRM 2009)
conference location
Honolulu, HI, USA
conference start
2009-04-18
conference end
2009-04-24
language
English
UGent publication?
yes
classification
C3
copyright statement
I have transferred the copyright for this publication to the publisher
id
837079
handle
http://hdl.handle.net/1854/LU-837079
date created
2010-01-25 14:59:07
date last changed
2010-04-21 14:34:06
@inproceedings{837079,
  abstract     = {Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used to map oxygen concentrations in hypoxic tissue. However, validation of pO2-measurements in vivo is difficult. In this study, an oxygen consuming phantom simulating oxygen perfusion in tissue is presented. The phantom consists of a hemodialysis filter of which the outer compartment is filled with a gel containing viable yeast cells. pO2-images reveal oxygen consumption by the yeast cells after injection of a bolus of oxygen rich hexafluorobenzene in the fibers of the hemodialysis filter. The developed phantom can be used for validation of Fluor-19 MRI oximetry.},
  author       = {Baete, Steven and De Deene, Yves},
  booktitle    = {Proceedings of the International Society for Magnetic Resonance in Medicine},
  language     = {eng},
  location     = {Honolulu, HI, USA},
  pages        = {832--832},
  title        = {An oxygen consuming phantom for simulating oxygen perfusion in tissue using 19F MRI oximetry},
  volume       = {17},
  year         = {2009},
}

Chicago
Baete, Steven, and Yves De Deene. 2009. “An Oxygen Consuming Phantom for Simulating Oxygen Perfusion in Tissue Using 19F MRI Oximetry.” In Proceedings of the International Society for Magnetic Resonance in Medicine, 17:832–832.
APA
Baete, S., & De Deene, Y. (2009). An oxygen consuming phantom for simulating oxygen perfusion in tissue using 19F MRI oximetry. Proceedings of the International Society for Magnetic Resonance in Medicine (Vol. 17, pp. 832–832). Presented at the ISMRM 17th Scientific Meeting and Exhibition (ISMRM 2009).
Vancouver
1.
Baete S, De Deene Y. An oxygen consuming phantom for simulating oxygen perfusion in tissue using 19F MRI oximetry. Proceedings of the International Society for Magnetic Resonance in Medicine. 2009. p. 832–832.
MLA
Baete, Steven, and Yves De Deene. “An Oxygen Consuming Phantom for Simulating Oxygen Perfusion in Tissue Using 19F MRI Oximetry.” Proceedings of the International Society for Magnetic Resonance in Medicine. Vol. 17. 2009. 832–832. Print.