The Suzuki-Miyaura reaction performed using a palladium-N-heterocyclic carbene catalyst and a weak inorganic base
- Author
- Frederic Izquierdo, Martin Corpet and Steven Nolan (UGent)
- Organization
- Abstract
- N-Heterocyclic carbenes (NHCs) have been shown to be useful ligands for the Suzuki-Miyaura cross-coupling at low catalyst loadings. We now report that the commercially available and air-stable [Pd(IPr)(cin)Cl] pre-catalyst permits the formation of various functionalized biaryls from aryl chlorides and boronic acids (37 examples) under very mild conditions using a mixture of ethanol/water as solvent and an inorganic base.
- Keywords
- Cross-coupling, N-heterocyclic carbenes, Palladium, Suzuki-Miyaura reaction, CROSS-COUPLING REACTIONS, ORTHO-SUBSTITUTED BIARYLS, TRANSITION-METAL-COMPLEXES, ARYL CHLORIDES, ROOM-TEMPERATURE, AQUEOUS-MEDIA, HETEROARYL CHLORIDES, ARYLBORONIC ACIDS, HIGHLY EFFICIENT, BUCHWALD-HARTWIG
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8168346
- MLA
- Izquierdo, Frederic, et al. “The Suzuki-Miyaura Reaction Performed Using a Palladium-N-Heterocyclic Carbene Catalyst and a Weak Inorganic Base.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, no. 9, 2015, pp. 1920–24.
- APA
- Izquierdo, F., Corpet, M., & Nolan, S. (2015). The Suzuki-Miyaura reaction performed using a palladium-N-heterocyclic carbene catalyst and a weak inorganic base. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, (9), 1920–1924.
- Chicago author-date
- Izquierdo, Frederic, Martin Corpet, and Steven Nolan. 2015. “The Suzuki-Miyaura Reaction Performed Using a Palladium-N-Heterocyclic Carbene Catalyst and a Weak Inorganic Base.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, no. 9: 1920–24.
- Chicago author-date (all authors)
- Izquierdo, Frederic, Martin Corpet, and Steven Nolan. 2015. “The Suzuki-Miyaura Reaction Performed Using a Palladium-N-Heterocyclic Carbene Catalyst and a Weak Inorganic Base.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (9): 1920–1924.
- Vancouver
- 1.Izquierdo F, Corpet M, Nolan S. The Suzuki-Miyaura reaction performed using a palladium-N-heterocyclic carbene catalyst and a weak inorganic base. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2015;(9):1920–4.
- IEEE
- [1]F. Izquierdo, M. Corpet, and S. Nolan, “The Suzuki-Miyaura reaction performed using a palladium-N-heterocyclic carbene catalyst and a weak inorganic base,” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, no. 9, pp. 1920–1924, 2015.
@article{8168346,
abstract = {N-Heterocyclic carbenes (NHCs) have been shown to be useful ligands for the Suzuki-Miyaura cross-coupling at low catalyst loadings. We now report that the commercially available and air-stable [Pd(IPr)(cin)Cl] pre-catalyst permits the formation of various functionalized biaryls from aryl chlorides and boronic acids (37 examples) under very mild conditions using a mixture of ethanol/water as solvent and an inorganic base.},
author = {Izquierdo, Frederic and Corpet, Martin and Nolan, Steven},
issn = {1434-193X},
journal = {EUROPEAN JOURNAL OF ORGANIC CHEMISTRY},
keywords = {Cross-coupling,N-heterocyclic carbenes,Palladium,Suzuki-Miyaura reaction,CROSS-COUPLING REACTIONS,ORTHO-SUBSTITUTED BIARYLS,TRANSITION-METAL-COMPLEXES,ARYL CHLORIDES,ROOM-TEMPERATURE,AQUEOUS-MEDIA,HETEROARYL CHLORIDES,ARYLBORONIC ACIDS,HIGHLY EFFICIENT,BUCHWALD-HARTWIG},
language = {eng},
number = {9},
pages = {1920--1924},
title = {The Suzuki-Miyaura reaction performed using a palladium-N-heterocyclic carbene catalyst and a weak inorganic base},
url = {http://dx.doi.org/10.1002/ejoc.201500043},
year = {2015},
}
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