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Stroke due to non-bacterial thrombotic endocarditis as initial presentation of breast invasive ductal carcinoma

Celine Detremerie (UGent) , Frank Timmermans (UGent) , Michel De Pauw (UGent) , Peter Gheeraert (UGent) , Dimitri Hemelsoet (UGent) , Jonas Toeback (UGent) , Thierry Bové (UGent) and Els Vandecasteele (UGent)
(2017) ACTA CLINICA BELGICA. 72(4). p.268-273
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Abstract
We present a case of a 71-year-old woman with recurrent stroke episodes due to non-bacterial thrombotic endocarditis (NBTE) leading to the diagnosis of an early-stage breast carcinoma. NBTE is associated with a variety of inflammatory states, including malignancy. NBTE presents itself with systemic embolization, mostly stroke. Treatment consists of treating the underlying condition and start of systemic anticoagulation therapy. Cardiac surgery is restricted to highly selected cases, since prognosis usually is limited by the neoplasm, which usually is in an advanced stage at time of diagnosis of NBTE. The malignancy usually is diagnosed prior to NBTE. Cases presenting with NBTE leading to the diagnosis of malignancy, however, are rarely reported. To our knowledge, we present the first case leading to the diagnosis of an early-stage breast carcinoma.
Keywords
Marantic endocarditis, Stroke, Non-bacterial thrombotic endocarditis (NBTE), Breast carcinoma, MARANTIC ENDOCARDITIS, SYSTEMIC EMBOLI, CANCER, ADENOCARCINOMA

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MLA
Detremerie, Celine, Frank Timmermans, Michel De Pauw, et al. “Stroke Due to Non-bacterial Thrombotic Endocarditis as Initial Presentation of Breast Invasive Ductal Carcinoma.” ACTA CLINICA BELGICA 72.4 (2017): 268–273. Print.
APA
Detremerie, C., Timmermans, F., De Pauw, M., Gheeraert, P., Hemelsoet, D., Toeback, J., Bové, T., et al. (2017). Stroke due to non-bacterial thrombotic endocarditis as initial presentation of breast invasive ductal carcinoma. ACTA CLINICA BELGICA, 72(4), 268–273.
Chicago author-date
Detremerie, Celine, Frank Timmermans, Michel De Pauw, Peter Gheeraert, Dimitri Hemelsoet, Jonas Toeback, Thierry Bové, and Els Vandecasteele. 2017. “Stroke Due to Non-bacterial Thrombotic Endocarditis as Initial Presentation of Breast Invasive Ductal Carcinoma.” Acta Clinica Belgica 72 (4): 268–273.
Chicago author-date (all authors)
Detremerie, Celine, Frank Timmermans, Michel De Pauw, Peter Gheeraert, Dimitri Hemelsoet, Jonas Toeback, Thierry Bové, and Els Vandecasteele. 2017. “Stroke Due to Non-bacterial Thrombotic Endocarditis as Initial Presentation of Breast Invasive Ductal Carcinoma.” Acta Clinica Belgica 72 (4): 268–273.
Vancouver
1.
Detremerie C, Timmermans F, De Pauw M, Gheeraert P, Hemelsoet D, Toeback J, et al. Stroke due to non-bacterial thrombotic endocarditis as initial presentation of breast invasive ductal carcinoma. ACTA CLINICA BELGICA. 2017;72(4):268–73.
IEEE
[1]
C. Detremerie et al., “Stroke due to non-bacterial thrombotic endocarditis as initial presentation of breast invasive ductal carcinoma,” ACTA CLINICA BELGICA, vol. 72, no. 4, pp. 268–273, 2017.
@article{8165388,
  abstract     = {We present a case of a 71-year-old woman with recurrent stroke episodes due to non-bacterial thrombotic endocarditis (NBTE) leading to the diagnosis of an early-stage breast carcinoma. NBTE is associated with a variety of inflammatory states, including malignancy. NBTE presents itself with systemic embolization, mostly stroke. Treatment consists of treating the underlying condition and start of systemic anticoagulation therapy. Cardiac surgery is restricted to highly selected cases, since prognosis usually is limited by the neoplasm, which usually is in an advanced stage at time of diagnosis of NBTE. The malignancy usually is diagnosed prior to NBTE. Cases presenting with NBTE leading to the diagnosis of malignancy, however, are rarely reported. To our knowledge, we present the first case leading to the diagnosis of an early-stage breast carcinoma.},
  author       = {Detremerie, Celine and Timmermans, Frank and De Pauw, Michel and Gheeraert, Peter and Hemelsoet, Dimitri and Toeback, Jonas and Bové, Thierry and Vandecasteele, Els},
  issn         = {1784-3286},
  journal      = {ACTA CLINICA BELGICA},
  keywords     = {Marantic endocarditis,Stroke,Non-bacterial thrombotic endocarditis (NBTE),Breast carcinoma,MARANTIC ENDOCARDITIS,SYSTEMIC EMBOLI,CANCER,ADENOCARCINOMA},
  language     = {eng},
  number       = {4},
  pages        = {268--273},
  title        = {Stroke due to non-bacterial thrombotic endocarditis as initial presentation of breast invasive ductal carcinoma},
  url          = {http://dx.doi.org/10.1080/17843286.2016.1219012},
  volume       = {72},
  year         = {2017},
}

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