Advanced search

Electro-anatomical mapping of the left atrium before and after cryothermal balloon isolation of the pulmonary veins

Author
Organization
Abstract
The 28 mm cryoballoon catheter is a device used for pulmonary vein isolation (PVI). The aim of this study was to evaluate the extent of the ablation in the antral regions of the left atrium. Eighteen patients with drug refractory, symptomatic, paroxysmal AF were enrolled. A 3D electroanatomic reconstruction of the left atrium was made before and after successful PVI with the 28 mm cryoballoon. Markers were placed at the ostium. Sixteen patients were mapped. Fourteen patients had 4 veins each, and 2 patients had a common ostium of the left sided veins. All separate ostia were isolated in the antral region. The two common ostia showed ostial isolation. There was a significant difference in vein size between the common (29 and 31 mm) and the separate ostia (19 +/- 4 mm) (p < 0.01). The performance of an additional segmental ablation if balloon PVI did not eliminate all electrical activity, did not influence the extent of the ablation. The earliest left atrial activation during sinus rhythm was located in the superior septal region before ablation in all patients. After ablation, two patients showed a substantial downward shift towards the middle and inferior septal region respectively (NS). Four patients demonstrated a slight downward shift of the first activation. In cryoballoon PVI, the majority of the veins undergo antral isolation. Veins with a diameter larger than the balloon, are isolated ostially. In individual cases, the left atrial activation sequence appears to be altered after ablation.
Keywords
Cryoballoon, Arrhythmia, Catheter ablation, Cryoablation, Ablation, Tachyarrhythmias, Atrial fibrillation, Pulmonary veins, TRANSVENOUS CATHETER CRYOABLATION, ABLATION, FIBRILLATION, EFFICACY, FEASIBILITY, JUNCTION, SAFETY

Citation

Please use this url to cite or link to this publication:

Chicago
Van Belle, Yves, Paul Knops, Petter Janse, Maximo Rivero-Ayerza, Emile Jessurun, Tamas Szili-Torok, and Luc Jordaens. 2009. “Electro-anatomical Mapping of the Left Atrium Before and After Cryothermal Balloon Isolation of the Pulmonary Veins.” Journal of Interventional Cardiac Electrophysiology 25 (1): 59–65.
APA
Van Belle, Yves, Knops, P., Janse, P., Rivero-Ayerza, M., Jessurun, E., Szili-Torok, T., & Jordaens, L. (2009). Electro-anatomical mapping of the left atrium before and after cryothermal balloon isolation of the pulmonary veins. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 25(1), 59–65.
Vancouver
1.
Van Belle Y, Knops P, Janse P, Rivero-Ayerza M, Jessurun E, Szili-Torok T, et al. Electro-anatomical mapping of the left atrium before and after cryothermal balloon isolation of the pulmonary veins. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY. 2009;25(1):59–65.
MLA
Van Belle, Yves et al. “Electro-anatomical Mapping of the Left Atrium Before and After Cryothermal Balloon Isolation of the Pulmonary Veins.” JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY 25.1 (2009): 59–65. Print.
@article{8151426,
  abstract     = {The 28 mm cryoballoon catheter is a device used for pulmonary vein isolation (PVI). The aim of this study was to evaluate the extent of the ablation in the antral regions of the left atrium. 
Eighteen patients with drug refractory, symptomatic, paroxysmal AF were enrolled. A 3D electroanatomic reconstruction of the left atrium was made before and after successful PVI with the 28 mm cryoballoon. Markers were placed at the ostium. Sixteen patients were mapped. Fourteen patients had 4 veins each, and 2 patients had a common ostium of the left sided veins. All separate ostia were isolated in the antral region. The two common ostia showed ostial isolation. There was a significant difference in vein size between the common (29 and 31 mm) and the separate ostia (19 +/- 4 mm) (p < 0.01). The performance of an additional segmental ablation if balloon PVI did not eliminate all electrical activity, did not influence the extent of the ablation. The earliest left atrial activation during sinus rhythm was located in the superior septal region before ablation in all patients. After ablation, two patients showed a substantial downward shift towards the middle and inferior septal region respectively (NS). Four patients demonstrated a slight downward shift of the first activation. 
In cryoballoon PVI, the majority of the veins undergo antral isolation. Veins with a diameter larger than the balloon, are isolated ostially. In individual cases, the left atrial activation sequence appears to be altered after ablation.},
  author       = {Van Belle, Yves and Knops, Paul and Janse, Petter and Rivero-Ayerza, Maximo and Jessurun, Emile and Szili-Torok, Tamas and Jordaens, Luc},
  issn         = {1383-875X},
  journal      = {JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY},
  keywords     = {Cryoballoon,Arrhythmia,Catheter ablation,Cryoablation,Ablation,Tachyarrhythmias,Atrial fibrillation,Pulmonary veins,TRANSVENOUS CATHETER CRYOABLATION,ABLATION,FIBRILLATION,EFFICACY,FEASIBILITY,JUNCTION,SAFETY},
  language     = {eng},
  number       = {1},
  pages        = {59--65},
  title        = {Electro-anatomical mapping of the left atrium before and after cryothermal balloon isolation of the pulmonary veins},
  url          = {http://dx.doi.org/10.1007/s10840-008-9344-9},
  volume       = {25},
  year         = {2009},
}

Altmetric
View in Altmetric
Web of Science
Times cited: