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Structure, regulation and function of gap junctions in liver

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Abstract
Gap junctions are a specialized group of cell-to-cell junctions that mediate direct intercellular communication between cells. They arise from the interaction of two hemichannels of adjacent cells, which in turn are composed of six connexin proteins. In liver, gap junctions are predominantly found in hepatocytes and play critical roles in virtually all phases of the hepatic life cycle, including cell growth, differentiation, liver-specific functionality and cell death. Liver gap junctions are directed through a broad variety of mechanisms ranging from epigenetic control of connexin expression to post-translational regulation of gap junction activity. This paper reviews established and novel aspects regarding the architecture, control and functional relevance of liver gap junctions.
Keywords
connexin, gap junction, liver, ADULT-RAT HEPATOCYTES, INTERCELLULAR COMMUNICATION, CELL-DEATH, CONNEXIN PHOSPHORYLATION, PRIMARY CULTURES, MOUSE-LIVER, POSTTRANSLATIONAL MODIFICATIONS, HEPATOCELLULAR-CARCINOMA, EXTRACELLULAR-MATRIX, PARTIAL-HEPATECTOMY

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Chicago
Willebrords, Joost, Sara Crespo Yanguas, Michaël Maes, Elke Decrock, Nan Wang, Luc Leybaert, Tereza Cristina da Silva, et al. 2015. “Structure, Regulation and Function of Gap Junctions in Liver.” Cell Communication and Adhesion 22 (2-6): 29–37.
APA
Willebrords, J., Crespo Yanguas, S., Maes, M., Decrock, E., Wang, N., Leybaert, L., da Silva, T. C., et al. (2015). Structure, regulation and function of gap junctions in liver. CELL COMMUNICATION AND ADHESION, 22(2-6), 29–37.
Vancouver
1.
Willebrords J, Crespo Yanguas S, Maes M, Decrock E, Wang N, Leybaert L, et al. Structure, regulation and function of gap junctions in liver. CELL COMMUNICATION AND ADHESION. 2015;22(2-6):29–37.
MLA
Willebrords, Joost et al. “Structure, Regulation and Function of Gap Junctions in Liver.” CELL COMMUNICATION AND ADHESION 22.2-6 (2015): 29–37. Print.
@article{8121343,
  abstract     = {Gap junctions are a specialized group of cell-to-cell junctions that mediate direct intercellular communication between cells. They arise from the interaction of two hemichannels of adjacent cells, which in turn are composed of six connexin proteins. In liver, gap junctions are predominantly found in hepatocytes and play critical roles in virtually all phases of the hepatic life cycle, including cell growth, differentiation, liver-specific functionality and cell death. Liver gap junctions are directed through a broad variety of mechanisms ranging from epigenetic control of connexin expression to post-translational regulation of gap junction activity. This paper reviews established and novel aspects regarding the architecture, control and functional relevance of liver gap junctions.},
  author       = {Willebrords, Joost and Crespo Yanguas, Sara and Maes, Micha{\"e}l and Decrock, Elke and Wang, Nan and Leybaert, Luc and da Silva, Tereza Cristina and Alves Pereira, Isabel Veloso and Jaeschke, Hartmut and Cogliati, Bruno and Vinken, Mathieu},
  issn         = {1541-9061},
  journal      = {CELL COMMUNICATION AND ADHESION},
  language     = {eng},
  number       = {2-6},
  pages        = {29--37},
  title        = {Structure, regulation and function of gap junctions in liver},
  url          = {http://dx.doi.org/10.3109/15419061.2016.1151875},
  volume       = {22},
  year         = {2015},
}

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