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Predictors of cardiac events after cardiac resynchronization therapy with tissue Doppler-derived parameters

(2007) JOURNAL OF CARDIAC FAILURE. 13(10). p.805-811
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Abstract
Background: To evaluate the prognostic value of tissue Doppler imaging (TDI)-derived parameters (E/E' ratio and Tei index) in heart failure (HF) patients who underwent cardiac resynchronization therapy (CRT). Methods and Results: The study comprised 74 consecutive HF patients (mean age 60 +/- 11 years) who underwent CRT. Echocardiography including TDI measurements was performed in all patients at baseline and 3 months after CRT. During a median follow-up period of 720 days (range 210 to 1020 days), 21 patients (28%) had events (8 deaths, and hospitalization for HF in the remaining 13). From the baseline clinical and echocardiography data, univariable Cox-regressions analysis revealed that only diabetes (hazard ratio [HR] 3.703, P <.01), E/A ratio (HR 3.492, P <.001), and E/E' ratio (HR 1.130, P <.001) were predictors for cardiac events. From the 3-month follow-up data, the E/A ratio (HR 2.988, P <.005), E/E' ratio (HR 1.170, P <.001), left ventricular ejection fraction (HR 0.835, P <.01), deceleration time (HR 0.977, P <.05), and the Tei index (HR 15.784, P <.001) were predictors for cardiac events. After multivariable analysis, only diabetes (HR 5.544, P <.05), the 3-month E/E' ratio (HR 1.229, P <.001), and change in Tei index (HR 32.174, P <.001) were independent predictors for cardiac events. Patients with a high baseline and 3-month follow-up E/E' ratio had an 88% cardiac event rate. Conclusions: The Tei index and E/E' ratio are independent predictors of poor response and cardiac events after CRT.
Keywords
echocardiography, prognosis, heart failure, cardiac resynchronization therapy, CONGESTIVE-HEART-FAILURE, ACUTE MYOCARDIAL-INFARCTION, RANDOMIZED CONTROLLED-TRIALS, LEFT-VENTRICULAR DYSFUNCTION, LONG-TERM SURVIVAL, PROGNOSTIC VALUE, DILATED CARDIOMYOPATHY, TEI-INDEX, GUIDELINE UPDATE, FILLING PATTERN

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Chicago
Soliman, Osama II, Dominic AMJ Theuns, Folkert J Ten Cate, Attila Nemes, Kadir Caliskan, Aggie HMM Balk, Wim B Vletter, Luc Jordaens, and Marcel L Geleijnse. 2007. “Predictors of Cardiac Events After Cardiac Resynchronization Therapy with Tissue Doppler-derived Parameters.” Journal of Cardiac Failure 13 (10): 805–811.
APA
Soliman, O. I., Theuns, D. A., Ten Cate, F. J., Nemes, A., Caliskan, K., Balk, A. H., Vletter, W. B., et al. (2007). Predictors of cardiac events after cardiac resynchronization therapy with tissue Doppler-derived parameters. JOURNAL OF CARDIAC FAILURE, 13(10), 805–811.
Vancouver
1.
Soliman OI, Theuns DA, Ten Cate FJ, Nemes A, Caliskan K, Balk AH, et al. Predictors of cardiac events after cardiac resynchronization therapy with tissue Doppler-derived parameters. JOURNAL OF CARDIAC FAILURE. 2007;13(10):805–11.
MLA
Soliman, Osama II, Dominic AMJ Theuns, Folkert J Ten Cate, et al. “Predictors of Cardiac Events After Cardiac Resynchronization Therapy with Tissue Doppler-derived Parameters.” JOURNAL OF CARDIAC FAILURE 13.10 (2007): 805–811. Print.
@article{8110118,
  abstract     = {Background: To evaluate the prognostic value of tissue Doppler imaging (TDI)-derived parameters (E/E' ratio and Tei index) in heart failure (HF) patients who underwent cardiac resynchronization therapy (CRT).
Methods and Results: The study comprised 74 consecutive HF patients (mean age 60 +/- 11 years) who underwent CRT. Echocardiography including TDI measurements was performed in all patients at baseline and 3 months after CRT. During a median follow-up period of 720 days (range 210 to 1020 days), 21 patients (28\%) had events (8 deaths, and hospitalization for HF in the remaining 13). From the baseline clinical and echocardiography data, univariable Cox-regressions analysis revealed that only diabetes (hazard ratio [HR] 3.703, P {\textlangle}.01), E/A ratio (HR 3.492, P {\textlangle}.001), and E/E' ratio (HR 1.130, P {\textlangle}.001) were predictors for cardiac events. From the 3-month follow-up data, the E/A ratio (HR 2.988, P {\textlangle}.005), E/E' ratio (HR 1.170, P {\textlangle}.001), left ventricular ejection fraction (HR 0.835, P {\textlangle}.01), deceleration time (HR 0.977, P {\textlangle}.05), and the Tei index (HR 15.784, P {\textlangle}.001) were predictors for cardiac events. After multivariable analysis, only diabetes (HR 5.544, P {\textlangle}.05), the 3-month E/E' ratio (HR 1.229, P {\textlangle}.001), and change in Tei index (HR 32.174, P {\textlangle}.001) were independent predictors for cardiac events. Patients with a high baseline and 3-month follow-up E/E' ratio had an 88\% cardiac event rate.
Conclusions: The Tei index and E/E' ratio are independent predictors of poor response and cardiac events after CRT.},
  author       = {Soliman, Osama II and Theuns, Dominic AMJ and Ten Cate, Folkert J and Nemes, Attila and Caliskan, Kadir and Balk, Aggie HMM and Vletter, Wim B and Jordaens, Luc and Geleijnse, Marcel L},
  issn         = {1071-9164},
  journal      = {JOURNAL OF CARDIAC FAILURE},
  language     = {eng},
  number       = {10},
  pages        = {805--811},
  title        = {Predictors of cardiac events after cardiac resynchronization therapy with tissue Doppler-derived parameters},
  url          = {http://dx.doi.org/10.1016/j.cardfail.2007.07.010},
  volume       = {13},
  year         = {2007},
}

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