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The history of target-controlled infusion

(2016) ANESTHESIA AND ANALGESIA. 122(1). p.56-69
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Abstract
Target-controlled infusion (TCI) is a technique of infusing IV drugs to achieve a user-defined predicted (target) drug concentration in a specific body compartment or tissue of interest. In this review, we describe the pharmacokinetic principles of TCI, the development of TCI systems, and technical and regulatory issues addressed in prototype development. We also describe the launch of the current clinically available systems.
Keywords
TOTAL INTRAVENOUS ANESTHESIA, COMPUTER-CONTROLLED INFUSION, 3-COMPARTMENT PHARMACOKINETIC MODEL, GENERAL-ANESTHESIA, BISPECTRAL INDEX, ASSISTED INFUSION, PLASMA-CONCENTRATIONS, DRIVEN DRUG-DELIVERY, LOWER ABDOMINAL-SURGERY, NITROUS-OXIDE ANESTHESIA

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Citation

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Chicago
Struys, Michel, Tom De Smet, John (Iain) B Glen, Hugo EM Vereecke, Anthony R Absalom, and Thomas W Schnider. 2016. “The History of Target-controlled Infusion.” Anesthesia and Analgesia 122 (1): 56–69.
APA
Struys, M., De Smet, T., Glen, J. (Iain) B., Vereecke, H. E., Absalom, A. R., & Schnider, T. W. (2016). The history of target-controlled infusion. ANESTHESIA AND ANALGESIA, 122(1), 56–69.
Vancouver
1.
Struys M, De Smet T, Glen J (Iain) B, Vereecke HE, Absalom AR, Schnider TW. The history of target-controlled infusion. ANESTHESIA AND ANALGESIA. 2016;122(1):56–69.
MLA
Struys, Michel et al. “The History of Target-controlled Infusion.” ANESTHESIA AND ANALGESIA 122.1 (2016): 56–69. Print.
@article{8052991,
  abstract     = {Target-controlled infusion (TCI) is a technique of infusing IV drugs to achieve a user-defined predicted (target) drug concentration in a specific body compartment or tissue of interest. In this review, we describe the pharmacokinetic principles of TCI, the development of TCI systems, and technical and regulatory issues addressed in prototype development. We also describe the launch of the current clinically available systems.},
  author       = {Struys, Michel and De Smet, Tom and Glen, John (Iain) B and Vereecke, Hugo EM and Absalom, Anthony R and Schnider, Thomas W},
  issn         = {0003-2999},
  journal      = {ANESTHESIA AND ANALGESIA},
  keywords     = {TOTAL INTRAVENOUS ANESTHESIA,COMPUTER-CONTROLLED INFUSION,3-COMPARTMENT PHARMACOKINETIC MODEL,GENERAL-ANESTHESIA,BISPECTRAL INDEX,ASSISTED INFUSION,PLASMA-CONCENTRATIONS,DRIVEN DRUG-DELIVERY,LOWER ABDOMINAL-SURGERY,NITROUS-OXIDE ANESTHESIA},
  language     = {eng},
  number       = {1},
  pages        = {56--69},
  title        = {The history of target-controlled infusion},
  url          = {http://dx.doi.org/10.1213/ANE.0000000000001008},
  volume       = {122},
  year         = {2016},
}

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