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Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool

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Abstract
Background: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP). Objective: We aimed (1) to determine PIP prevalence in older nursing home (NH) residents with polypharmacy using the GheOP3S-tool and (2) to identify those PIPs that are most frequently detected. Method: A cross-sectional study was carried out between February and June 2014 in 10 NHs in Belgium, supplied by a community pharmacy chain. For each NH, 40 residents (>70 years, using >5 chronic drugs) were included. PIP prevalence was determined using the GheOP3S-tool. Results: 400 NH residents were included [mean age (±SD) 86.2 (±6.3) years; median number of drugs (±IQR) 10 (7–12)]. A total of 1728 PIPs were detected in 387 (97 %) participants (Median 4; IQR 2–6). The most prevalent items can be assigned to three categories: long-term use of central nervous system drugs (i.e. benzodiazepines, antidepressants and antipsychotics), use of anticholinergic drugs (mutual combinations and with underlying constipation/dementia) and underuse of osteoporosis prophylaxis. Conclusion: Screening for PIP by means of the GheOP3S-tool revealed a high prevalence of PIP among older NH residents with polypharmacy. This finding urges for initiatives on the patient-level, but also on a broader, institutional level.
Keywords
Aged, Belgium, GheOP(3)S, Inappropriate prescribing, Nursing homes, PIP, CARE HOMES, DRUG-USE, MEDICATION, QUALITY, INTERVENTIONS

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Citation

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MLA
Tommelein, Eline et al. “Potentially Inappropriate Prescribing in Nursing Home Residents Detected with the Community Pharmacist Specific GheOP3S-tool.” INTERNATIONAL JOURNAL OF CLINICAL PHARMACY 38.5 (2016): 1063–1068. Print.
APA
Tommelein, E., Mehuys, E., Petrovic, M., Somers, A., Van Damme, C., PATTYN, E., Mattelin, K., et al. (2016). Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool. INTERNATIONAL JOURNAL OF CLINICAL PHARMACY, 38(5), 1063–1068.
Chicago author-date
Tommelein, Eline, Els Mehuys, Mirko Petrovic, Annemie Somers, Charlotte Van Damme, EVA PATTYN, Kristof Mattelin, and Koen Boussery. 2016. “Potentially Inappropriate Prescribing in Nursing Home Residents Detected with the Community Pharmacist Specific GheOP3S-tool.” International Journal of Clinical Pharmacy 38 (5): 1063–1068.
Chicago author-date (all authors)
Tommelein, Eline, Els Mehuys, Mirko Petrovic, Annemie Somers, Charlotte Van Damme, EVA PATTYN, Kristof Mattelin, and Koen Boussery. 2016. “Potentially Inappropriate Prescribing in Nursing Home Residents Detected with the Community Pharmacist Specific GheOP3S-tool.” International Journal of Clinical Pharmacy 38 (5): 1063–1068.
Vancouver
1.
Tommelein E, Mehuys E, Petrovic M, Somers A, Van Damme C, PATTYN E, et al. Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool. INTERNATIONAL JOURNAL OF CLINICAL PHARMACY. 2016;38(5):1063–8.
IEEE
[1]
E. Tommelein et al., “Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool,” INTERNATIONAL JOURNAL OF CLINICAL PHARMACY, vol. 38, no. 5, pp. 1063–1068, 2016.
@article{8048086,
  abstract     = {Background: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP). 
Objective: We aimed (1) to determine PIP prevalence in older nursing home (NH) residents with polypharmacy using the GheOP3S-tool and (2) to identify those PIPs that are most frequently detected. 
Method: A cross-sectional study was carried out between February and June 2014 in 10 NHs in Belgium, supplied by a community pharmacy chain. For each NH, 40 residents (>70 years, using >5 chronic drugs) were included. PIP prevalence was determined using the GheOP3S-tool. Results: 400 NH residents were included [mean age (±SD) 86.2 (±6.3) years; median number of drugs (±IQR) 10 (7–12)]. A total of 1728 PIPs were detected in 387 (97 %) participants (Median 4; IQR 2–6). The most prevalent items can be assigned to three categories: long-term use of central nervous system drugs (i.e. benzodiazepines, antidepressants and antipsychotics), use of anticholinergic drugs (mutual combinations and with underlying constipation/dementia) and underuse of osteoporosis prophylaxis. 
Conclusion: Screening for PIP by means of the GheOP3S-tool revealed a high prevalence of PIP among older NH residents with polypharmacy. This finding urges for initiatives on the patient-level, but also on a broader, institutional level.},
  author       = {Tommelein, Eline and Mehuys, Els and Petrovic, Mirko and Somers, Annemie and Van Damme, Charlotte and PATTYN, EVA and Mattelin, Kristof and Boussery, Koen},
  issn         = {2210-7703},
  journal      = {INTERNATIONAL JOURNAL OF CLINICAL PHARMACY},
  keywords     = {Aged,Belgium,GheOP(3)S,Inappropriate prescribing,Nursing homes,PIP,CARE HOMES,DRUG-USE,MEDICATION,QUALITY,INTERVENTIONS},
  language     = {eng},
  number       = {5},
  pages        = {1063--1068},
  title        = {Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool},
  url          = {http://dx.doi.org/10.1007/s11096-016-0366-6},
  volume       = {38},
  year         = {2016},
}

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