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Current controversies and challenges in allergic rhinitis management

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Abstract
There are many obstacles in the path of effective allergy management, in general, and allergic rhinitis (AR) control, in particular. Chief among them are: insufficient symptom relief in some patients provided by some currently considered first-line AR treatments in real life; an over-reliance on randomized controlled trials to direct AR guideline recommendations; the need for a broader interpretation of the AR evidence base (to include randomized controlled trials and real-life studies); poorly designed and interpreted studies; and lack of an AR control concept and common language of control. These controversies are fully reviewed here and challenging solutions have been presented.
Keywords
allergic rhinitis, clinical relevance, control, guidelines, randomized controlled trials, real life, VISUAL ANALOG SCALE, QUALITY-OF-LIFE, BILASTINE 20 MG, REAL-LIFE, COMBINATION TREATMENT, INTRANASAL THERAPY, ARIA GUIDELINES, EUROPEAN-UNION, PRIMARY-CARE, DOUBLE-BLIND

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MLA
Price, David et al. “Current Controversies and Challenges in Allergic Rhinitis Management.” EXPERT REVIEW OF CLINICAL IMMUNOLOGY 11.11 (2015): 1205–1217. Print.
APA
Price, D., Smith, P., Hellings, P., Papadopoulos, N., Fokkens, W., Muraro, A., Murray, R., et al. (2015). Current controversies and challenges in allergic rhinitis management. EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 11(11), 1205–1217.
Chicago author-date
Price, David, Pete Smith, Peter Hellings, Nikos Papadopoulos, Wytske Fokkens, Antonella Muraro, Ruth Murray, et al. 2015. “Current Controversies and Challenges in Allergic Rhinitis Management.” Expert Review of Clinical Immunology 11 (11): 1205–1217.
Chicago author-date (all authors)
Price, David, Pete Smith, Peter Hellings, Nikos Papadopoulos, Wytske Fokkens, Antonella Muraro, Ruth Murray, Alison Chisholm, Pascal Demoly, Glenis Scadding, Joaquim Mullol, Phil Lieberman, Claus Bachert, Ralph Moesges, Dermot Ryan, and Jean Bousquet. 2015. “Current Controversies and Challenges in Allergic Rhinitis Management.” Expert Review of Clinical Immunology 11 (11): 1205–1217.
Vancouver
1.
Price D, Smith P, Hellings P, Papadopoulos N, Fokkens W, Muraro A, et al. Current controversies and challenges in allergic rhinitis management. EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2015;11(11):1205–17.
IEEE
[1]
D. Price et al., “Current controversies and challenges in allergic rhinitis management,” EXPERT REVIEW OF CLINICAL IMMUNOLOGY, vol. 11, no. 11, pp. 1205–1217, 2015.
@article{8030126,
  abstract     = {There are many obstacles in the path of effective allergy management, in general, and allergic rhinitis (AR) control, in particular. Chief among them are: insufficient symptom relief in some patients provided by some currently considered first-line AR treatments in real life; an over-reliance on randomized controlled trials to direct AR guideline recommendations; the need for a broader interpretation of the AR evidence base (to include randomized controlled trials and real-life studies); poorly designed and interpreted studies; and lack of an AR control concept and common language of control. These controversies are fully reviewed here and challenging solutions have been presented.},
  author       = {Price, David and Smith, Pete and Hellings, Peter and Papadopoulos, Nikos and Fokkens, Wytske and Muraro, Antonella and Murray, Ruth and Chisholm, Alison and Demoly, Pascal and Scadding, Glenis and Mullol, Joaquim and Lieberman, Phil and Bachert, Claus and Moesges, Ralph and Ryan, Dermot and Bousquet, Jean},
  issn         = {1744-666X},
  journal      = {EXPERT REVIEW OF CLINICAL IMMUNOLOGY},
  keywords     = {allergic rhinitis,clinical relevance,control,guidelines,randomized controlled trials,real life,VISUAL ANALOG SCALE,QUALITY-OF-LIFE,BILASTINE 20 MG,REAL-LIFE,COMBINATION TREATMENT,INTRANASAL THERAPY,ARIA GUIDELINES,EUROPEAN-UNION,PRIMARY-CARE,DOUBLE-BLIND},
  language     = {eng},
  number       = {11},
  pages        = {1205--1217},
  title        = {Current controversies and challenges in allergic rhinitis management},
  url          = {http://dx.doi.org/10.1586/1744666X.2015.1081814},
  volume       = {11},
  year         = {2015},
}

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