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Clinical and MRI outcome of an osteochondral scaffold plug for the treatment of cartilage lesions in the knee

Aad Dhollander, Peter Verdonk, Karl Almqvist, René Verdonk and Jan Victor UGent (2015) ACTA ORTHOPAEDICA BELGICA. 81(4). p.629-638
abstract
Conflicting clinical outcomes have been reported recently with the use of an osteochondral scaffold plugs for cartilage repair in the knee. In this study, twenty patients were consecutively treated for their cartilage lesions with the synthetic plug technique. These patients were prospectively clinically evaluated with a mean follow-up of 34.15 months. Magnetic resonance imaging (MRI) was used for morphologic analysis of the cartilage repair. The patients included in this study showed a significant gradual clinical improvement after the osteochondral scaffold plug. However, this clinical improvement was not confirmed by the MRI findings of this cohort study. Subchondral bone changes were seen in all patients on MRI and deficient filling of the defect was noticed in in 30.7% of the cases at 24 months of follow-up. There was no evidence found to support osteoconductive bone ingrowth. Therefore, the use of this type of osteochondral scaffold plug in osteochondral repair is questionable.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
cartilage, knee, osteochondral, scaffolds, AUTOLOGOUS CHONDROCYTE TRANSPLANTATION, VISUAL ANALOG SCALE, ARTICULAR-CARTILAGE, REPAIR TISSUE, SCORE KOOS, DEFECTS, INJURY, BONE, REGENERATION, IMPLANTATION
journal title
ACTA ORTHOPAEDICA BELGICA
Acta Orthop. Belg.
volume
81
issue
4
pages
629 - 638
Web of Science type
Article
Web of Science id
000371106400011
JCR category
ORTHOPEDICS
JCR impact factor
0.837 (2015)
JCR rank
57/74 (2015)
JCR quartile
4 (2015)
ISSN
0001-6462
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
8028018
handle
http://hdl.handle.net/1854/LU-8028018
date created
2016-07-06 11:11:10
date last changed
2016-12-19 15:42:32
@article{8028018,
  abstract     = {Conflicting clinical outcomes have been reported recently with the use of an osteochondral scaffold plugs for cartilage repair in the knee. In this study, twenty patients were consecutively treated for their cartilage lesions with the synthetic plug technique. These patients were prospectively clinically evaluated with a mean follow-up of 34.15 months. Magnetic resonance imaging (MRI) was used for morphologic analysis of the cartilage repair. The patients included in this study showed a significant gradual clinical improvement after the osteochondral scaffold plug. However, this clinical improvement was not confirmed by the MRI findings of this cohort study. Subchondral bone changes were seen in all patients on MRI and deficient filling of the defect was noticed in in 30.7\% of the cases at 24 months of follow-up. There was no evidence found to support osteoconductive bone ingrowth. Therefore, the use of this type of osteochondral scaffold plug in osteochondral repair is questionable.},
  author       = {Dhollander, Aad and Verdonk, Peter and Almqvist, Karl and Verdonk, Ren{\'e} and Victor, Jan},
  issn         = {0001-6462},
  journal      = {ACTA ORTHOPAEDICA BELGICA},
  keyword      = {cartilage,knee,osteochondral,scaffolds,AUTOLOGOUS CHONDROCYTE TRANSPLANTATION,VISUAL ANALOG SCALE,ARTICULAR-CARTILAGE,REPAIR TISSUE,SCORE KOOS,DEFECTS,INJURY,BONE,REGENERATION,IMPLANTATION},
  language     = {eng},
  number       = {4},
  pages        = {629--638},
  title        = {Clinical and MRI outcome of an osteochondral scaffold plug for the treatment of cartilage lesions in the knee},
  volume       = {81},
  year         = {2015},
}

Chicago
Dhollander, Aad, Peter Verdonk, Karl Almqvist, René Verdonk, and Jan Victor. 2015. “Clinical and MRI Outcome of an Osteochondral Scaffold Plug for the Treatment of Cartilage Lesions in the Knee.” Acta Orthopaedica Belgica 81 (4): 629–638.
APA
Dhollander, A., Verdonk, P., Almqvist, K., Verdonk, R., & Victor, J. (2015). Clinical and MRI outcome of an osteochondral scaffold plug for the treatment of cartilage lesions in the knee. ACTA ORTHOPAEDICA BELGICA, 81(4), 629–638.
Vancouver
1.
Dhollander A, Verdonk P, Almqvist K, Verdonk R, Victor J. Clinical and MRI outcome of an osteochondral scaffold plug for the treatment of cartilage lesions in the knee. ACTA ORTHOPAEDICA BELGICA. 2015;81(4):629–38.
MLA
Dhollander, Aad, Peter Verdonk, Karl Almqvist, et al. “Clinical and MRI Outcome of an Osteochondral Scaffold Plug for the Treatment of Cartilage Lesions in the Knee.” ACTA ORTHOPAEDICA BELGICA 81.4 (2015): 629–638. Print.