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The risk of transmitting cutaneous malignancy through skin transplantation: a literature-based risk assessment

(2015) CELL AND TISSUE BANKING. 16(4). p.503-512
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Abstract
According to the European Union Tissues and Cells Directives donation of tissue is contraindicated in the presence of or a previous history of malignant disease, with the exception of cutaneous basal cell carcinoma. Skin cancer is the most common cancer. Due to ultraviolet light exposure and increasing life expectancy an increasing prevalence of malignant or premalignant skin lesions is observed, which may result in a decline of the availability of skin for transplantation. A risk assessment based on published studies and expert opinion was performed in order to investigate the risk of transmitting malignant or premalignant skin lesions through tissue transplantation, and more particular through skin transplantation. The scarcity of data concerning cancer transmission in tissue transplantation was challenging. Circumstantial evidence, available for organ transplantation, was used to develop the following policy proposal for skin transplantation and cutaneous tumours. Malignant melanoma is an absolute contraindication for the donation of skin and also of other tissues, whereas, non-lesional skin and other tissues of a donor with non-melanoma skin cancer (basal cell and squamous cell carcinoma) or with a premalignant skin lesion can be considered for transplantation. The above mentioned protocol proposal might serve as a prototype for analogous protocols for non-cutaneous malignancies.
Keywords
Transmission, Cutaneous malignancies, Tissue transplantation, CANCER SCREENING PROTOCOL, Risk assessment, Guidelines, HUMAN-PAPILLOMAVIRUS INFECTION, ALLOGRAFT RECIPIENTS, MULTIORGAN DONOR, PHYSICAL-EXAMINATION, TISSUE-BANKS, MELANOMA, TRANSMISSION, EXPERIENCE, LESIONS

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Citation

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MLA
Bosma, Sarah et al. “The Risk of Transmitting Cutaneous Malignancy Through Skin Transplantation: a Literature-based Risk Assessment.” CELL AND TISSUE BANKING 16.4 (2015): 503–512. Print.
APA
Bosma, S., Van Wijk, M. J., Richters, C. D., & Beele, H. (2015). The risk of transmitting cutaneous malignancy through skin transplantation: a literature-based risk assessment. CELL AND TISSUE BANKING, 16(4), 503–512.
Chicago author-date
Bosma, Sarah, Marja J Van Wijk, Cornelia D Richters, and Hilde Beele. 2015. “The Risk of Transmitting Cutaneous Malignancy Through Skin Transplantation: a Literature-based Risk Assessment.” Cell and Tissue Banking 16 (4): 503–512.
Chicago author-date (all authors)
Bosma, Sarah, Marja J Van Wijk, Cornelia D Richters, and Hilde Beele. 2015. “The Risk of Transmitting Cutaneous Malignancy Through Skin Transplantation: a Literature-based Risk Assessment.” Cell and Tissue Banking 16 (4): 503–512.
Vancouver
1.
Bosma S, Van Wijk MJ, Richters CD, Beele H. The risk of transmitting cutaneous malignancy through skin transplantation: a literature-based risk assessment. CELL AND TISSUE BANKING. 2015;16(4):503–12.
IEEE
[1]
S. Bosma, M. J. Van Wijk, C. D. Richters, and H. Beele, “The risk of transmitting cutaneous malignancy through skin transplantation: a literature-based risk assessment,” CELL AND TISSUE BANKING, vol. 16, no. 4, pp. 503–512, 2015.
@article{8024776,
  abstract     = {According to the European Union Tissues and Cells Directives donation of tissue is contraindicated in the presence of or a previous history of malignant disease, with the exception of cutaneous basal cell carcinoma. Skin cancer is the most common cancer. Due to ultraviolet light exposure and increasing life expectancy an increasing prevalence of malignant or premalignant skin lesions is observed, which may result in a decline of the availability of skin for transplantation. A risk assessment based on published studies and expert opinion was performed in order to investigate the risk of transmitting malignant or premalignant skin lesions through tissue transplantation, and more particular through skin transplantation. The scarcity of data concerning cancer transmission in tissue transplantation was challenging. Circumstantial evidence, available for organ transplantation, was used to develop the following policy proposal for skin transplantation and cutaneous tumours. Malignant melanoma is an absolute contraindication for the donation of skin and also of other tissues, whereas, non-lesional skin and other tissues of a donor with non-melanoma skin cancer (basal cell and squamous cell carcinoma) or with a premalignant skin lesion can be considered for transplantation. The above mentioned protocol proposal might serve as a prototype for analogous protocols for non-cutaneous malignancies.},
  author       = {Bosma, Sarah and Van Wijk, Marja J and Richters, Cornelia D and Beele, Hilde},
  issn         = {1389-9333},
  journal      = {CELL AND TISSUE BANKING},
  keywords     = {Transmission,Cutaneous malignancies,Tissue transplantation,CANCER SCREENING PROTOCOL,Risk assessment,Guidelines,HUMAN-PAPILLOMAVIRUS INFECTION,ALLOGRAFT RECIPIENTS,MULTIORGAN DONOR,PHYSICAL-EXAMINATION,TISSUE-BANKS,MELANOMA,TRANSMISSION,EXPERIENCE,LESIONS},
  language     = {eng},
  number       = {4},
  pages        = {503--512},
  title        = {The risk of transmitting cutaneous malignancy through skin transplantation: a literature-based risk assessment},
  url          = {http://dx.doi.org/10.1007/s10561-015-9497-6},
  volume       = {16},
  year         = {2015},
}

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