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Analytical profiling, modeling and transdermal/transmucosal characteristics of bioactive N-alkylamides

Bart De Spiegeleer (UGent) , Jente Boonen (UGent) , Christian Burvenich (UGent) , Phillip Blondeel (UGent) and Bram Baert (UGent)
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Abstract
N-alkylamides are a group of bioactive molecules found in several plants. Extracts and formulations derived from these plants are not only used orally, but are applied on the skin and buccal mucosa as well. However, there is no specific information available about the intrinsic local pharmacokinetics of N-alkylamides after topical application, questioning the role of this mode of administration. Therefore, we investigated the transdermal and transmucosal behaviour of spilanthol, a prominent N-alkylamide, in a commercial Spilanthes extract, two mouth gels and different propylene glycol (PG)/H20 solutions.

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Chicago
De Spiegeleer, Bart, Jente Boonen, Christian Burvenich, Phillip Blondeel, and Bram Baert. 2009. “Analytical Profiling, Modeling and Transdermal/transmucosal Characteristics of Bioactive N-alkylamides.” In Abstracts & Posters 21st International Symposium on Pharmaceutical & Biomedical Analysis.
APA
De Spiegeleer, B., Boonen, J., Burvenich, C., Blondeel, P., & Baert, B. (2009). Analytical profiling, modeling and transdermal/transmucosal characteristics of bioactive N-alkylamides. Abstracts & Posters 21st International Symposium on Pharmaceutical & Biomedical Analysis. Presented at the 21st International Symposium on Pharmaceutical & Biomedical Analysis.
Vancouver
1.
De Spiegeleer B, Boonen J, Burvenich C, Blondeel P, Baert B. Analytical profiling, modeling and transdermal/transmucosal characteristics of bioactive N-alkylamides. Abstracts & Posters 21st International Symposium on Pharmaceutical & Biomedical Analysis. 2009.
MLA
De Spiegeleer, Bart, Jente Boonen, Christian Burvenich, et al. “Analytical Profiling, Modeling and Transdermal/transmucosal Characteristics of Bioactive N-alkylamides.” Abstracts & Posters 21st International Symposium on Pharmaceutical & Biomedical Analysis. 2009. Print.
@inproceedings{779640,
  abstract     = {N-alkylamides are a group of bioactive molecules found in several plants. Extracts and formulations derived from these plants are not only used orally, but are applied on the skin and buccal mucosa as well. However, there is no specific information available about the intrinsic local pharmacokinetics of N-alkylamides after topical application, questioning the role of this mode of administration. Therefore, we investigated the transdermal and transmucosal behaviour of spilanthol, a prominent N-alkylamide, in a commercial Spilanthes extract, two mouth gels and different propylene glycol (PG)/H20 solutions.},
  author       = {De Spiegeleer, Bart and Boonen, Jente and Burvenich, Christian and Blondeel, Phillip and Baert, Bram},
  booktitle    = {Abstracts \& Posters 21st International Symposium on Pharmaceutical \& Biomedical Analysis},
  language     = {eng},
  location     = {Orlando, FL, USA},
  title        = {Analytical profiling, modeling and transdermal/transmucosal characteristics of bioactive N-alkylamides},
  year         = {2009},
}