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Design and analysis of LAB on chip liquid crystal biosensor

Hamidreza Azarinia (UGent) , Jeroen Beeckman (UGent) and Kristiaan Neyts (UGent)
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Abstract
Mach-Zehnder interferometer photonic circuits are widely used in optical sensing. An important application of the Mach-Zehnder photonic circuit in particular that we envision is the detection of bio-molecules. The cause of perturbation is proposed to be a liquid crystal cavity sensitive to biological specimen. Liquid crystal materials with their birefringent properties and bulk reorientation due to surface effects are interesting for bio-sensing applications [1, 2]. Liquid crystal molecules tend to align planar at a liquid crystal/water interface. By adding small amounts of phospholipid mixtures to the water, the orientation evolves to homeotropic alignment. This process is reversible. In order to use this process as a detection method, the liquid crystal is deposited into the holes in one branch of the Mach-Zehnder device and a fluid (e.g. water) covers the entire surface of the hole through a micro fluidic channel. Compatibility of liquid crystal with glass fiber and the integrated photonic circuits are the advantages that come together in a Mach-Zehnder fabricated on a glass substrate. The technical steps of design and fabrication and the full-wave analysis of the structure using finite difference time domain (FDTD) method is presented.
Keywords
Liquid Crystal, FDTD, Bio-sensing, Mach-Zehnder

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Citation

Please use this url to cite or link to this publication:

Chicago
Azarinia, Hamidreza, Jeroen Beeckman, and Kristiaan Neyts. 2009. “Design and Analysis of LAB on Chip Liquid Crystal Biosensor.” In European Conference on Liquid Crystals, 10th, Proceedings, O45–O45.
APA
Azarinia, H., Beeckman, J., & Neyts, K. (2009). Design and analysis of LAB on chip liquid crystal biosensor. European Conference on Liquid Crystals, 10th, Proceedings (pp. O45–O45). Presented at the 10th European Conference on Liquid Crystals.
Vancouver
1.
Azarinia H, Beeckman J, Neyts K. Design and analysis of LAB on chip liquid crystal biosensor. European Conference on Liquid Crystals, 10th, Proceedings. 2009. p. O45–O45.
MLA
Azarinia, Hamidreza, Jeroen Beeckman, and Kristiaan Neyts. “Design and Analysis of LAB on Chip Liquid Crystal Biosensor.” European Conference on Liquid Crystals, 10th, Proceedings. 2009. O45–O45. Print.
@inproceedings{777561,
  abstract     = {Mach-Zehnder interferometer photonic circuits are widely used in optical sensing. An important application of the Mach-Zehnder photonic circuit in particular that we envision is the detection of bio-molecules. The cause of perturbation is proposed to be a liquid crystal cavity sensitive to biological specimen. Liquid crystal materials with their birefringent properties and bulk reorientation due to surface effects are interesting for bio-sensing applications [1, 2]. Liquid crystal molecules tend to align planar at a liquid crystal/water interface. By adding small amounts of phospholipid mixtures to the water, the orientation evolves to homeotropic alignment. This process is reversible. In order to use this process as a detection method, the liquid crystal is deposited into the holes in one branch of the Mach-Zehnder device and a fluid (e.g. water) covers the entire surface of the hole through a micro fluidic channel. Compatibility of liquid crystal with glass fiber and the integrated photonic circuits are the advantages that come together in a Mach-Zehnder fabricated on a glass substrate. The technical steps of design and fabrication and the full-wave analysis of the structure using finite difference time domain (FDTD) method is presented.},
  author       = {Azarinia, Hamidreza and Beeckman, Jeroen and Neyts, Kristiaan},
  booktitle    = {European Conference on Liquid Crystals, 10th, Proceedings},
  keyword      = {Liquid Crystal,FDTD,Bio-sensing,Mach-Zehnder},
  language     = {eng},
  location     = {Colmar, France},
  pages        = {O45--O45},
  title        = {Design and analysis of LAB on chip liquid crystal biosensor},
  url          = {http://lfb.issp.bas.bg/{\texttildelow}viki/ECLC09/Oral\_contributions\_O\_01-80/O\_45\_Azarinia.pdf},
  year         = {2009},
}