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Quantitative proton magnetic resonance spectroscopy in presence of sidebands

Mahir Ozdemir UGent, Yves De Deene UGent, Eric Achten UGent, Yves D'Asseler UGent and Ignace Lemahieu UGent (2007) 2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3. p.1008-1011
abstract
We perform Proton Magnetic Resonance Spectroscopy (MRS) without water suppression in contrast to traditional water-suppressed MRS. The preserved water signal can be used as a reference for the absolute quantification of metabolites, reducing the total measurement time. However, the non-water-suppressed spectra can be contaminated by gradient-induced frequency modulations resulting in sidebands in the spectrum. Sidebands may obscure the metabolite resonances of interest, thereby rendering the spectral analysis and quantification problematic. To this end, we present a correction technique to remove sidebands. The proposed method utilizes the phase of an external reference of single resonance to observe the time-varying the static field fluctuation induced by gradient-vibrations then deconvolves this phase contamination from the desired signal obtained under the same experimental conditions. The method is evaluated by phantom and in vivo measurements.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
keyword
sidebands, absolute quantification, IN-VIVO, SOLVENT SUPPRESSION, WATER, BRAIN, magnetic resonance spectroscopy, water suppression
in
2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3
I S BIOMED IMAGING
pages
4 pages
publisher
IEEE
place of publication
New York
conference name
4th IEEE International Symposium on Biomedical Imaging - Macro to Nano
conference location
Arlington, VA
conference start
2007-04-12
conference end
2007-04-15
Web of Science type
Proceedings Paper
Web of Science id
000252957300253
ISSN
1945-7928
ISBN
978-1-4244-0671-5
DOI
10.1109/ISBI.2007.357025
language
English
UGent publication?
yes
classification
P1
id
750530
handle
http://hdl.handle.net/1854/LU-750530
date created
2009-09-18 13:12:53
date last changed
2010-01-18 15:14:23
@inproceedings{750530,
  abstract     = {We perform Proton Magnetic Resonance Spectroscopy (MRS) without water suppression in contrast to traditional water-suppressed MRS. The preserved water signal can be used as a reference for the absolute quantification of metabolites, reducing the total measurement time. However, the non-water-suppressed spectra can be contaminated by gradient-induced frequency modulations resulting in sidebands in the spectrum. Sidebands may obscure the metabolite resonances of interest, thereby rendering the spectral analysis and quantification problematic. To this end, we present a correction technique to remove sidebands. The proposed method utilizes the phase of an external reference of single resonance to observe the time-varying the static field fluctuation induced by gradient-vibrations then deconvolves this phase contamination from the desired signal obtained under the same experimental conditions. The method is evaluated by phantom and in vivo measurements.},
  author       = {Ozdemir, Mahir and De Deene, Yves and Achten, Eric and D'Asseler, Yves and Lemahieu, Ignace},
  booktitle    = {2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3},
  isbn         = {978-1-4244-0671-5},
  issn         = {1945-7928},
  keyword      = {sidebands,absolute quantification,IN-VIVO,SOLVENT SUPPRESSION,WATER,BRAIN,magnetic resonance spectroscopy,water suppression},
  language     = {eng},
  location     = {Arlington, VA},
  pages        = {1008--1011},
  publisher    = {IEEE},
  title        = {Quantitative proton magnetic resonance spectroscopy in presence of sidebands},
  url          = {http://dx.doi.org/10.1109/ISBI.2007.357025},
  year         = {2007},
}

Chicago
Ozdemir, Mahir, Yves De Deene, Eric Achten, Yves D’Asseler, and Ignace Lemahieu. 2007. “Quantitative Proton Magnetic Resonance Spectroscopy in Presence of Sidebands.” In 2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3, 1008–1011. New York: IEEE.
APA
Ozdemir, M., De Deene, Y., Achten, E., D’Asseler, Y., & Lemahieu, I. (2007). Quantitative proton magnetic resonance spectroscopy in presence of sidebands. 2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3 (pp. 1008–1011). Presented at the 4th IEEE International Symposium on Biomedical Imaging - Macro to Nano, New York: IEEE.
Vancouver
1.
Ozdemir M, De Deene Y, Achten E, D’Asseler Y, Lemahieu I. Quantitative proton magnetic resonance spectroscopy in presence of sidebands. 2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3. New York: IEEE; 2007. p. 1008–11.
MLA
Ozdemir, Mahir, Yves De Deene, Eric Achten, et al. “Quantitative Proton Magnetic Resonance Spectroscopy in Presence of Sidebands.” 2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3. New York: IEEE, 2007. 1008–1011. Print.