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A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry

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capillary gas chromatography, QUANTITATIVE-DETERMINATION, headspace, derivatization, alkylating agents, METHYL METHANESULFONATE, ETHYL METHANESULFONATE, HUMAN-PLASMA, DNA-DAMAGE, BUSULFAN, SOLVENTS, MS, mass spectrometry, pharmaceutical products, PHASE MICROEXTRACTION SPME, DRUG SUBSTANCES

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Citation

Please use this url to cite or link to this publication:

Chicago
Alzaga, Roberto, Robert W. Ryan, Karen Taylor-Worth, Andrew M. Lipczynski, Roman Szucs, and Patrick Sandra. 2007. “A Generic Approach for the Determination of Residues of Alkylating Agents in Active Pharmaceutical Ingredients by in Situ Derivatization-headspace-gas Chromatography-mass Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis 45 (3): 472–479.
APA
Alzaga, R., Ryan, R. W., Taylor-Worth, K., Lipczynski, A. M., Szucs, R., & Sandra, P. (2007). A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 45(3), 472–479.
Vancouver
1.
Alzaga R, Ryan RW, Taylor-Worth K, Lipczynski AM, Szucs R, Sandra P. A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2007;45(3):472–9.
MLA
Alzaga, Roberto et al. “A Generic Approach for the Determination of Residues of Alkylating Agents in Active Pharmaceutical Ingredients by in Situ Derivatization-headspace-gas Chromatography-mass Spectrometry.” JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 45.3 (2007): 472–479. Print.
@article{747656,
  author       = {Alzaga, Roberto and Ryan, Robert W. and Taylor-Worth, Karen and Lipczynski, Andrew M. and Szucs, Roman and Sandra, Patrick},
  issn         = {0731-7085},
  journal      = {JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS},
  language     = {eng},
  number       = {3},
  pages        = {472--479},
  title        = {A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry},
  url          = {http://dx.doi.org/10.1016/j.jpba.2007.07.017},
  volume       = {45},
  year         = {2007},
}

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