A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry
- Author
- Roberto Alzaga, Robert W. Ryan, Karen Taylor-Worth, Andrew M. Lipczynski, Roman Szucs (UGent) and Patrick Sandra (UGent)
- Organization
- Keywords
- capillary gas chromatography, QUANTITATIVE-DETERMINATION, headspace, derivatization, alkylating agents, METHYL METHANESULFONATE, ETHYL METHANESULFONATE, HUMAN-PLASMA, DNA-DAMAGE, BUSULFAN, SOLVENTS, MS, mass spectrometry, pharmaceutical products, PHASE MICROEXTRACTION SPME, DRUG SUBSTANCES
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-747656
- MLA
- Alzaga, Roberto, et al. “A Generic Approach for the Determination of Residues of Alkylating Agents in Active Pharmaceutical Ingredients by in Situ Derivatization-Headspace-Gas Chromatography-Mass Spectrometry.” JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. 45, no. 3, 2007, pp. 472–79, doi:10.1016/j.jpba.2007.07.017.
- APA
- Alzaga, R., Ryan, R. W., Taylor-Worth, K., Lipczynski, A. M., Szucs, R., & Sandra, P. (2007). A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 45(3), 472–479. https://doi.org/10.1016/j.jpba.2007.07.017
- Chicago author-date
- Alzaga, Roberto, Robert W. Ryan, Karen Taylor-Worth, Andrew M. Lipczynski, Roman Szucs, and Patrick Sandra. 2007. “A Generic Approach for the Determination of Residues of Alkylating Agents in Active Pharmaceutical Ingredients by in Situ Derivatization-Headspace-Gas Chromatography-Mass Spectrometry.” JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 45 (3): 472–79. https://doi.org/10.1016/j.jpba.2007.07.017.
- Chicago author-date (all authors)
- Alzaga, Roberto, Robert W. Ryan, Karen Taylor-Worth, Andrew M. Lipczynski, Roman Szucs, and Patrick Sandra. 2007. “A Generic Approach for the Determination of Residues of Alkylating Agents in Active Pharmaceutical Ingredients by in Situ Derivatization-Headspace-Gas Chromatography-Mass Spectrometry.” JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 45 (3): 472–479. doi:10.1016/j.jpba.2007.07.017.
- Vancouver
- 1.Alzaga R, Ryan RW, Taylor-Worth K, Lipczynski AM, Szucs R, Sandra P. A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2007;45(3):472–9.
- IEEE
- [1]R. Alzaga, R. W. Ryan, K. Taylor-Worth, A. M. Lipczynski, R. Szucs, and P. Sandra, “A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry,” JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. 45, no. 3, pp. 472–479, 2007.
@article{747656,
author = {{Alzaga, Roberto and Ryan, Robert W. and Taylor-Worth, Karen and Lipczynski, Andrew M. and Szucs, Roman and Sandra, Patrick}},
issn = {{0731-7085}},
journal = {{JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS}},
keywords = {{capillary gas chromatography,QUANTITATIVE-DETERMINATION,headspace,derivatization,alkylating agents,METHYL METHANESULFONATE,ETHYL METHANESULFONATE,HUMAN-PLASMA,DNA-DAMAGE,BUSULFAN,SOLVENTS,MS,mass spectrometry,pharmaceutical products,PHASE MICROEXTRACTION SPME,DRUG SUBSTANCES}},
language = {{eng}},
number = {{3}},
pages = {{472--479}},
title = {{A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry}},
url = {{http://doi.org/10.1016/j.jpba.2007.07.017}},
volume = {{45}},
year = {{2007}},
}
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