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Economic impact of the preparation scenario for cytotoxic drugs: an observational study

Johan Vandenbroucke (UGent) and Hugo Robays (UGent)
(2008) EJHP PRACTICE. 14(5). p.37-42
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Abstract
Aim: To evaluate the financial impact of three different preparation and conservation scenarios for cytotoxic drugs. Method: In scenario one we discarded the residual fraction of the drug after each preparation. In scenario two we used the residual fraction of the vial until the end of the day. In scenario three we used the residual fraction of the vial until the chemical/physical expiry date. To analyse the economic impact of the three scenarios, we looked at 3,086 preparations during July and August 2006. Results and discussion: A major difference in cost was found between the three scenarios, namely: Euros 872,413, Euros 807,309 and Euros 754,442 for scenarios one, two and three respectively. Savings varied between a minimum of Euros 52,867 (7%) and a maximum of Euros 117,971 (15%) for the observation period of two months, or an average of Euros 17 to Euros 38 per preparation. Conclusion: When cytotoxic medicines are prepared under rigorous conditions, pharmacists can contribute to substantial economic savings.
Keywords
BAGS, CHEMICAL-STABILITY, INFUSION SOLUTIONS

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Please use this url to cite or link to this publication:

Chicago
Vandenbroucke, Johan, and Hugo Robays. 2008. “Economic Impact of the Preparation Scenario for Cytotoxic Drugs: An Observational Study.” Ejhp Practice 14 (5): 37–42.
APA
Vandenbroucke, J., & Robays, H. (2008). Economic impact of the preparation scenario for cytotoxic drugs: an observational study. EJHP PRACTICE, 14(5), 37–42.
Vancouver
1.
Vandenbroucke J, Robays H. Economic impact of the preparation scenario for cytotoxic drugs: an observational study. EJHP PRACTICE. 2008;14(5):37–42.
MLA
Vandenbroucke, Johan, and Hugo Robays. “Economic Impact of the Preparation Scenario for Cytotoxic Drugs: An Observational Study.” EJHP PRACTICE 14.5 (2008): 37–42. Print.
@article{747013,
  abstract     = {Aim: To evaluate the financial impact of three different preparation and conservation scenarios for cytotoxic drugs.

Method: In scenario one we discarded the residual fraction of the drug after each preparation. In scenario two we used the residual fraction of the vial until the end of the day. In scenario three we used the residual fraction of the vial until the chemical/physical expiry date. To analyse the economic impact of the three scenarios, we looked at 3,086 preparations during July and August 2006.

Results and discussion: A major difference in cost was found between the three scenarios, namely: Euros 872,413, Euros 807,309 and Euros 754,442 for scenarios one, two and three respectively. Savings varied between a minimum of Euros 52,867 (7%) and a maximum of Euros 117,971 (15%) for the observation period of two months, or an average of Euros 17 to Euros 38 per preparation.

Conclusion: When cytotoxic medicines are prepared under rigorous conditions, pharmacists can contribute to substantial economic savings.},
  author       = {Vandenbroucke, Johan and Robays, Hugo},
  issn         = {1781-9989},
  journal      = {EJHP PRACTICE},
  keywords     = {BAGS,CHEMICAL-STABILITY,INFUSION SOLUTIONS},
  language     = {eng},
  number       = {5},
  pages        = {37--42},
  title        = {Economic impact of the preparation scenario for cytotoxic drugs: an observational study},
  volume       = {14},
  year         = {2008},
}

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