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On-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry using a microflow nebulizer inserted in the laser ablation chamber

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Organization
Abstract
Laser ablation ICP-MS (inductively coupled plasma mass spectrometry) is becoming one of the most important analytical techniques for fast determination of trace impurities in solid samples. Quantification of analytical results requires matrix-matched standards, which are in some cases (e.g., high-purity metals, proteins separated by 2D gel electrophoresis) difficult to obtain or prepare. In order to overcome the quantification problem a special arrangement for on-line solution-based calibration has been proposed in laser ablation ICP-MS by the insertion of a microflow nebulizer in the laser ablation chamber. This arrangement allows an easy, accurate and precise quantification by on-line isotope dilution using a defined standard solution with an isotope enriched tracer nebulized to the laser-ablated sample material. An ideal matrix matching in LA-ICP-MS is therefore obtained during the measurement. The figures of merit of this arrangement with a microflow nebulizer inserted in the laser ablation chamber and applications of on-line isotope dilution in LA-ICP-MS on two different types of sample material (NIST glass SRM 612 and NIST apple leaves SRM 1515) will be described.

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MLA
Pickhardt, Carola, et al. “On-Line Isotope Dilution in Laser Ablation Inductively Coupled Plasma Mass Spectrometry Using a Microflow Nebulizer Inserted in the Laser Ablation Chamber.” International Journal of Mass Spectrometry, vol. 248, no. 3, 2006, pp. 136–41, doi:10.1016/j.ijms.2005.11.001.
APA
Pickhardt, C., Izmer, A., Zoriy, M., Schaumlöffel, D., & Becker, J. S. (2006). On-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry using a microflow nebulizer inserted in the laser ablation chamber. International Journal of Mass Spectrometry, 248(3), 136–141. https://doi.org/10.1016/j.ijms.2005.11.001
Chicago author-date
Pickhardt, Carola, Andrei Izmer, Miroslav Zoriy, Dirk Schaumlöffel, and J. Sabine Becker. 2006. “On-Line Isotope Dilution in Laser Ablation Inductively Coupled Plasma Mass Spectrometry Using a Microflow Nebulizer Inserted in the Laser Ablation Chamber.” International Journal of Mass Spectrometry 248 (3): 136–41. https://doi.org/10.1016/j.ijms.2005.11.001.
Chicago author-date (all authors)
Pickhardt, Carola, Andrei Izmer, Miroslav Zoriy, Dirk Schaumlöffel, and J. Sabine Becker. 2006. “On-Line Isotope Dilution in Laser Ablation Inductively Coupled Plasma Mass Spectrometry Using a Microflow Nebulizer Inserted in the Laser Ablation Chamber.” International Journal of Mass Spectrometry 248 (3): 136–141. doi:10.1016/j.ijms.2005.11.001.
Vancouver
1.
Pickhardt C, Izmer A, Zoriy M, Schaumlöffel D, Becker JS. On-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry using a microflow nebulizer inserted in the laser ablation chamber. International journal of mass spectrometry. 2006;248(3):136–41.
IEEE
[1]
C. Pickhardt, A. Izmer, M. Zoriy, D. Schaumlöffel, and J. S. Becker, “On-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry using a microflow nebulizer inserted in the laser ablation chamber,” International journal of mass spectrometry, vol. 248, no. 3, pp. 136–141, 2006.
@article{733762,
  abstract     = {{Laser ablation ICP-MS (inductively coupled plasma mass spectrometry) is becoming one of the most important analytical techniques for fast determination of trace impurities in solid samples. Quantification of analytical results requires matrix-matched standards, which are in some cases (e.g., high-purity metals, proteins separated by 2D gel electrophoresis) difficult to obtain or prepare. In order to overcome the quantification problem a special arrangement for on-line solution-based calibration has been proposed in laser ablation ICP-MS by the insertion of a microflow nebulizer in the laser ablation chamber. This arrangement allows an easy, accurate and precise quantification by on-line isotope dilution using a defined standard solution with an isotope enriched tracer nebulized to the laser-ablated sample material. An ideal matrix matching in LA-ICP-MS is therefore obtained during the measurement. The figures of merit of this arrangement with a microflow nebulizer inserted in the laser ablation chamber and applications of on-line isotope dilution in LA-ICP-MS on two different types of sample material (NIST glass SRM 612 and NIST apple leaves SRM 1515) will be described.}},
  author       = {{Pickhardt, Carola and Izmer, Andrei and Zoriy, Miroslav and Schaumlöffel, Dirk and Becker, J. Sabine}},
  issn         = {{1387-3806}},
  journal      = {{International journal of mass spectrometry}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{136--141}},
  title        = {{On-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry using a microflow nebulizer inserted in the laser ablation chamber}},
  url          = {{http://doi.org/10.1016/j.ijms.2005.11.001}},
  volume       = {{248}},
  year         = {{2006}},
}

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