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Correcting phase contrast artefacts in X-ray CT imaging

Yoni De Witte (UGent), Matthieu Boone (UGent), Jelle Vlassenbroeck (UGent), Manuel Dierick (UGent), Bert Masschaele (UGent), Luc Van Hoorebeke (UGent) and Veerle Cnudde (UGent)
Author
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Abstract
When going to higher resolution in X-ray transmission CT, one of the biggest problems is the appearance of phase contrast. Achieving high resolution usually means scanning very small and thus very low absorbing objects, especially in medical and biological applications. Since the absorption signal for such samples becomes very small, the contribution of the phase contrast signal to the projection image is no longer negligible. This phase signal, which is due to small angle refraction of the X-rays in the sample, results in severe artifacts in the reconstructed slices when using conventional reconstruction algorithms for transmission CT. The appearance of such phase artifacts can be prevented by using a method called Bronnikov Aided Correction, which applies a filtering operation on the projection images that almost completely removes the phase signal. This method is used to reconstruct a CT scan of a horse biopsy. Results are compared with those of a standard reconstruction.
Keywords
RECONSTRUCTION, RETRIEVAL, MICROTOMOGRAPHY, TOMOGRAPHY, refraction, biomedical imaging, X-ray tomography

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Chicago
De Witte, Yoni, Matthieu Boone, Jelle Vlassenbroeck, Manuel Dierick, Bert Masschaele, Luc Van Hoorebeke, and Veerle Cnudde. 2009. “Correcting Phase Contrast Artefacts in X-ray CT Imaging.” In 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), 574–577. New York, NY, USA: IEEE.
APA
De Witte, Y., Boone, M., Vlassenbroeck, J., Dierick, M., Masschaele, B., Van Hoorebeke, L., & Cnudde, V. (2009). Correcting phase contrast artefacts in X-ray CT imaging. 2009 IEEE International symposium on biomedical imaging: from nano to macro (ISBI) (pp. 574–577). Presented at the 2009 IEEE International symposium on Biomedical Imaging: From Nano to Macro (ISBI), New York, NY, USA: IEEE.
Vancouver
1.
De Witte Y, Boone M, Vlassenbroeck J, Dierick M, Masschaele B, Van Hoorebeke L, et al. Correcting phase contrast artefacts in X-ray CT imaging. 2009 IEEE International symposium on biomedical imaging: from nano to macro (ISBI). New York, NY, USA: IEEE; 2009. p. 574–7.
MLA
De Witte, Yoni, Matthieu Boone, Jelle Vlassenbroeck, et al. “Correcting Phase Contrast Artefacts in X-ray CT Imaging.” 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI). New York, NY, USA: IEEE, 2009. 574–577. Print.
@inproceedings{725774,
  abstract     = {When going to higher resolution in X-ray transmission CT, one of the biggest problems is the appearance of phase contrast. Achieving high resolution usually means scanning very small and thus very low absorbing objects, especially in medical and biological applications. Since the absorption signal for such samples becomes very small, the contribution of the phase contrast signal to the projection image is no longer negligible. This phase signal, which is due to small angle refraction of the X-rays in the sample, results in severe artifacts in the reconstructed slices when using conventional reconstruction algorithms for transmission CT. The appearance of such phase artifacts can be prevented by using a method called Bronnikov Aided Correction, which applies a filtering operation on the projection images that almost completely removes the phase signal. This method is used to reconstruct a CT scan of a horse biopsy. Results are compared with those of a standard reconstruction.},
  author       = {De Witte, Yoni and Boone, Matthieu and Vlassenbroeck, Jelle and Dierick, Manuel and Masschaele, Bert and Van Hoorebeke, Luc and Cnudde, Veerle},
  booktitle    = {2009 IEEE International symposium on biomedical imaging: from nano to macro (ISBI)},
  isbn         = {9781424439317},
  keyword      = {RECONSTRUCTION,RETRIEVAL,MICROTOMOGRAPHY,TOMOGRAPHY,refraction,biomedical imaging,X-ray tomography},
  language     = {eng},
  location     = {Boston, MA, USA},
  pages        = {574--577},
  publisher    = {IEEE},
  title        = {Correcting phase contrast artefacts in X-ray CT imaging},
  url          = {http://dx.doi.org/10.1109/ISBI.2009.5193112},
  year         = {2009},
}

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