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Age-related changes in binaural interaction at brainstem level

Lindsey Van Yper, KATRIEN VERMEIRE, EDDY DE VEL, Andy J Beynon and Ingeborg Dhooge UGent (2016) EAR AND HEARING. 37(4). p.434-442
abstract
Objectives: Age-related hearing loss hampers the ability to understand speech in adverse listening conditions. This is attributed to a complex interaction of changes in the peripheral and central auditory system. One aspect that may deteriorate across the lifespan is binaural interaction. The present study investigates binaural interaction at the level of the auditory brainstem. It is hypothesized that brainstem binaural interaction deteriorates with advancing age. Design: Forty-two subjects of various age participated in the study. Auditory brainstem responses (ABRs) were recorded using clicks and 500 Hz tone-bursts. ABRs were elicited by monaural right, monaural left, and binaural stimulation. Binaural interaction was investigated in two ways. First, grand averages of the binaural interaction component were computed for each age group. Second, wave V characteristics of the binaural ABR were compared with those of the summed left and right ABRs. Results: Binaural interaction in the click ABR was demonstrated by shorter latencies and smaller amplitudes in the binaural compared with the summed monaural responses. For 500 Hz tone-burst ABR, no latency differences were found. However, amplitudes were significantly smaller in the binaural than summed monaural condition. An age-effect was found for 500 Hz tone-burst, but not for click ABR. Conclusions: Brainstem binaural interaction seems to decline with age. Interestingly, these changes seem to be stimulus-dependent.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
age-related changes, binaural processing, aging, auditory brainstem response, binaural interaction, ABR, binaural hearing, AUDITORY EVOKED-POTENTIALS, MIDDLE-LATENCY, RESPONSES
journal title
EAR AND HEARING
Ear Hear.
volume
37
issue
4
pages
434 - 442
Web of Science type
Article
Web of Science id
000379371600014
JCR category
OTORHINOLARYNGOLOGY
JCR impact factor
2.842 (2016)
JCR rank
5/42 (2016)
JCR quartile
1 (2016)
ISSN
0196-0202
DOI
10.1097/AUD.0000000000000274
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
7198585
handle
http://hdl.handle.net/1854/LU-7198585
date created
2016-04-29 12:20:29
date last changed
2017-07-06 12:04:53
@article{7198585,
  abstract     = {Objectives: Age-related hearing loss hampers the ability to understand speech in adverse listening conditions. This is attributed to a complex interaction of changes in the peripheral and central auditory system. One aspect that may deteriorate across the lifespan is binaural interaction. The present study investigates binaural interaction at the level of the auditory brainstem. It is hypothesized that brainstem binaural interaction deteriorates with advancing age.
Design: Forty-two subjects of various age participated in the study. Auditory brainstem responses (ABRs) were recorded using clicks and 500 Hz tone-bursts. ABRs were elicited by monaural right, monaural left, and binaural stimulation. Binaural interaction was investigated in two ways. First, grand averages of the binaural interaction component were computed for each age group. Second, wave V characteristics of the binaural ABR were compared with those of the summed left and right ABRs.
Results: Binaural interaction in the click ABR was demonstrated by shorter latencies and smaller amplitudes in the binaural compared with the summed monaural responses. For 500 Hz tone-burst ABR, no latency differences were found. However, amplitudes were significantly smaller in the binaural than summed monaural condition. An age-effect was found for 500 Hz tone-burst, but not for click ABR.
Conclusions: Brainstem binaural interaction seems to decline with age. Interestingly, these changes seem to be stimulus-dependent.},
  author       = {Van Yper, Lindsey and VERMEIRE, KATRIEN and DE VEL, EDDY and Beynon, Andy J and Dhooge, Ingeborg},
  issn         = {0196-0202},
  journal      = {EAR AND HEARING},
  keyword      = {age-related changes,binaural processing,aging,auditory brainstem response,binaural interaction,ABR,binaural hearing,AUDITORY EVOKED-POTENTIALS,MIDDLE-LATENCY,RESPONSES},
  language     = {eng},
  number       = {4},
  pages        = {434--442},
  title        = {Age-related changes in binaural interaction at brainstem level},
  url          = {http://dx.doi.org/10.1097/AUD.0000000000000274},
  volume       = {37},
  year         = {2016},
}

Chicago
Van Yper, Lindsey, KATRIEN VERMEIRE, EDDY DE VEL, Andy J Beynon, and Ingeborg Dhooge. 2016. “Age-related Changes in Binaural Interaction at Brainstem Level.” Ear and Hearing 37 (4): 434–442.
APA
Van Yper, L., VERMEIRE, K., DE VEL, E., Beynon, A. J., & Dhooge, I. (2016). Age-related changes in binaural interaction at brainstem level. EAR AND HEARING, 37(4), 434–442.
Vancouver
1.
Van Yper L, VERMEIRE K, DE VEL E, Beynon AJ, Dhooge I. Age-related changes in binaural interaction at brainstem level. EAR AND HEARING. 2016;37(4):434–42.
MLA
Van Yper, Lindsey, KATRIEN VERMEIRE, EDDY DE VEL, et al. “Age-related Changes in Binaural Interaction at Brainstem Level.” EAR AND HEARING 37.4 (2016): 434–442. Print.