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Genome sequence of the recombinant protein production host Pichia pastoris

(2009) NATURE BIOTECHNOLOGY. 27(6). p.561-U104
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Abstract
The methylotrophic yeast Pichia pastoris is widely used for the production of proteins and as a model organism for studying peroxisomal biogenesis and methanol assimilation. P. pastoris strains capable of human-type N-glycosylation are now available, which increases the utility of this organism for biopharmaceutical production. Despite its biotechnological importance, relatively few genetic tools or engineered strains have been generated for P. pastoris. To facilitate progress in these areas, we present the 9.43 Mbp genomic sequence of the GS115 strain of P. pastoris. We also provide manually curated annotation for its 5,313 protein-coding genes.

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Citation

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MLA
De Schutter, Kristof, et al. “Genome Sequence of the Recombinant Protein Production Host Pichia Pastoris.” NATURE BIOTECHNOLOGY, vol. 27, no. 6, 2009, pp. 561-U104, doi:10.1038/nbt.1544.
APA
De Schutter, K., Lin, Y.-C., Tiels, P., Van Hecke, A., Glinka, S., Weber-Lehmann, J., … Callewaert, N. (2009). Genome sequence of the recombinant protein production host Pichia pastoris. NATURE BIOTECHNOLOGY, 27(6), 561-U104. https://doi.org/10.1038/nbt.1544
Chicago author-date
De Schutter, Kristof, Yao-Cheng Lin, Petra Tiels, Annelies Van Hecke, S Glinka, J Weber-Lehmann, Pierre Rouzé, Yves Van de Peer, and Nico Callewaert. 2009. “Genome Sequence of the Recombinant Protein Production Host Pichia Pastoris.” NATURE BIOTECHNOLOGY 27 (6): 561-U104. https://doi.org/10.1038/nbt.1544.
Chicago author-date (all authors)
De Schutter, Kristof, Yao-Cheng Lin, Petra Tiels, Annelies Van Hecke, S Glinka, J Weber-Lehmann, Pierre Rouzé, Yves Van de Peer, and Nico Callewaert. 2009. “Genome Sequence of the Recombinant Protein Production Host Pichia Pastoris.” NATURE BIOTECHNOLOGY 27 (6): 561-U104. doi:10.1038/nbt.1544.
Vancouver
1.
De Schutter K, Lin Y-C, Tiels P, Van Hecke A, Glinka S, Weber-Lehmann J, et al. Genome sequence of the recombinant protein production host Pichia pastoris. NATURE BIOTECHNOLOGY. 2009;27(6):561-U104.
IEEE
[1]
K. De Schutter et al., “Genome sequence of the recombinant protein production host Pichia pastoris,” NATURE BIOTECHNOLOGY, vol. 27, no. 6, pp. 561-U104, 2009.
@article{719136,
  abstract     = {{The methylotrophic yeast Pichia pastoris is widely used for the production of proteins and as a model organism for studying peroxisomal biogenesis and methanol assimilation. P. pastoris strains capable of human-type N-glycosylation are now available, which increases the utility of this organism for biopharmaceutical production. Despite its biotechnological importance, relatively few genetic tools or engineered strains have been generated for P. pastoris. To facilitate progress in these areas, we present the 9.43 Mbp genomic sequence of the GS115 strain of P. pastoris. We also provide manually curated annotation for its 5,313 protein-coding genes.}},
  author       = {{De Schutter, Kristof and Lin, Yao-Cheng and Tiels, Petra and Van Hecke, Annelies and Glinka, S and Weber-Lehmann, J and Rouzé, Pierre and Van de Peer, Yves and Callewaert, Nico}},
  issn         = {{1087-0156}},
  journal      = {{NATURE BIOTECHNOLOGY}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{561--U104}},
  title        = {{Genome sequence of the recombinant protein production host Pichia pastoris}},
  url          = {{http://doi.org/10.1038/nbt.1544}},
  volume       = {{27}},
  year         = {{2009}},
}

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