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Optimization of geriatric pharmacotherapy : role of multifaceted cooperation in the hospital setting

(2016) DRUGS & AGING. 33(3). p.179-188
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Abstract
Because older patients are more vulnerable to adverse drug-related events, there is a need to ensure appropriate pharmacotherapy in these patients. This narrative review describes approaches to improve pharmacotherapy in older people in hospital setting. Screening to identify older patients at risk of drug-related problems (DRP) and adverse drug reactions (ADR) is the first critical step within a multistep approach to geriatric pharmacotherapy. Two methods that have been developed are the GerontoNet ADR risk score and Brighton ADR (BADRI) model, which take into account a number of factors, the most important of which is the number of medicines. In order to reduce potentially inappropriate prescribing (PIP) in older patients, different types of interventions exist, such as pharmacist-led medication reviews, educational interventions, computerized decision support systems, and comprehensive geriatric assessment. The effects of these interventions have been studied, sometimes in a multifaceted approach, by combining different techniques. None of the existing interventions shows a clear beneficial effect on patients’ health outcomes if applied in isolation. However, when these interventions are combined within the context of a multidisciplinary team, positive effects on patients’ health outcomes can be expected. Appropriate geriatric pharmacotherapy, global assessment of patients’ clinical and functional parameters, and integration of skills from different health care professionals are needed to address medical complexity of older adults.
Keywords
ADVERSE DRUG-REACTIONS, POTENTIALLY INAPPROPRIATE MEDICATIONS, RANDOMIZED-CONTROLLED-TRIAL, PHYSICIAN ORDER ENTRY, COMPLEX OLDER-ADULTS, INTENSIVE-CARE-UNIT, ELDERLY-PATIENTS, RISK-FACTORS, PRESCRIBING INDICATORS, CLINICAL-PHARMACOLOGY

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Citation

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MLA
Petrovic, Mirko, Annemie Somers, and Graziano Onder. “Optimization of Geriatric Pharmacotherapy : Role of Multifaceted Cooperation in the Hospital Setting.” DRUGS & AGING 33.3 (2016): 179–188. Print.
APA
Petrovic, M., Somers, A., & Onder, G. (2016). Optimization of geriatric pharmacotherapy : role of multifaceted cooperation in the hospital setting. DRUGS & AGING, 33(3), 179–188.
Chicago author-date
Petrovic, Mirko, Annemie Somers, and Graziano Onder. 2016. “Optimization of Geriatric Pharmacotherapy : Role of Multifaceted Cooperation in the Hospital Setting.” Drugs & Aging 33 (3): 179–188.
Chicago author-date (all authors)
Petrovic, Mirko, Annemie Somers, and Graziano Onder. 2016. “Optimization of Geriatric Pharmacotherapy : Role of Multifaceted Cooperation in the Hospital Setting.” Drugs & Aging 33 (3): 179–188.
Vancouver
1.
Petrovic M, Somers A, Onder G. Optimization of geriatric pharmacotherapy : role of multifaceted cooperation in the hospital setting. DRUGS & AGING. 2016;33(3):179–88.
IEEE
[1]
M. Petrovic, A. Somers, and G. Onder, “Optimization of geriatric pharmacotherapy : role of multifaceted cooperation in the hospital setting,” DRUGS & AGING, vol. 33, no. 3, pp. 179–188, 2016.
@article{7080669,
  abstract     = {Because older patients are more vulnerable to adverse drug-related events, there is a need to ensure appropriate pharmacotherapy in these patients. This narrative review describes approaches to improve pharmacotherapy in older people in hospital setting. Screening to identify older patients at risk of drug-related problems (DRP) and adverse drug reactions (ADR) is the first critical step within a multistep approach to geriatric pharmacotherapy. Two methods that have been developed are the GerontoNet ADR risk score and Brighton ADR (BADRI) model, which take into account a number of factors, the most important of which is the number of medicines.  In order to reduce potentially inappropriate prescribing (PIP) in older patients, different types of interventions exist, such as pharmacist-led medication reviews, educational interventions, computerized decision support systems, and comprehensive geriatric assessment. The effects of these interventions have been studied, sometimes in a multifaceted approach, by combining different techniques. None of the existing interventions shows a clear beneficial effect on patients’ health outcomes if applied in isolation. However, when these interventions are combined within the context of a multidisciplinary team, positive effects on patients’ health outcomes can be expected. Appropriate geriatric pharmacotherapy, global assessment of patients’ clinical and functional parameters, and integration of skills from different health care professionals are needed to address medical complexity of older adults.},
  author       = {Petrovic, Mirko and Somers, Annemie and Onder, Graziano},
  issn         = {1170-229X},
  journal      = {DRUGS & AGING},
  keywords     = {ADVERSE DRUG-REACTIONS,POTENTIALLY INAPPROPRIATE MEDICATIONS,RANDOMIZED-CONTROLLED-TRIAL,PHYSICIAN ORDER ENTRY,COMPLEX OLDER-ADULTS,INTENSIVE-CARE-UNIT,ELDERLY-PATIENTS,RISK-FACTORS,PRESCRIBING INDICATORS,CLINICAL-PHARMACOLOGY},
  language     = {eng},
  number       = {3},
  pages        = {179--188},
  title        = {Optimization of geriatric pharmacotherapy : role of multifaceted cooperation in the hospital setting},
  url          = {http://dx.doi.org/10.1007/s40266-016-0352-7},
  volume       = {33},
  year         = {2016},
}

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