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Remodeling and repair in rhinosinusitis

Jean-Baptiste Watelet UGent, Jean-Michel Dogne and François Mullier (2015) CURRENT ALLERGY AND ASTHMA REPORTS. 15(6).
abstract
Remodeling refers to the development of specific but potentially irreversible structural changes in tissue. Caucasian eosinophilic chronic rhinosinusitis (CRS) with polyps associated or not with cystic fibrosis was discriminated by edema from CRS without nasal polyps, characterized by extensive fibrotic fields. However, changes in epithelial and extracellular matrix structures are common findings in all types of chronic inflammatory diseases of upper airways, but rarely specific and highly variable in extend. Recent studies have shown that remodeling in CRS appears to occur in parallel, rather than purely subsequent to inflammation. Furthermore, some preferential remodeling associations can be recognized. Tremendous efforts have been put in research on coagulation factors, cytokines, growth factors, and proteases supporting all phases of upper airway remodeling. The current exploration of other CRS sub-groups and of the particular link with concomitant asthma aims to optimize the classification of CRS and its staging modes and to develop novel therapies.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
MATRIX METALLOPROTEINASES, STAPHYLOCOCCUS-AUREUS, UPPER AIRWAYS, ALLERGIC RHINITIS, FIBRIN STRUCTURE, GROWTH-FACTOR, IN-VITRO, EXPRESSION, Chronic rhinosinusitis, Nasal polyps, Tissue remodeling, Tissue repair, NASAL POLYPS, FACTOR-XIII
journal title
CURRENT ALLERGY AND ASTHMA REPORTS
Curr. Allergy Asthma Rep.
volume
15
issue
6
article number
34
pages
7 pages
Web of Science type
Review
Web of Science id
000357428700006
JCR category
ALLERGY
JCR impact factor
3.127 (2015)
JCR rank
9/25 (2015)
JCR quartile
2 (2015)
ISSN
1529-7322
DOI
10.1007/s11882-015-0531-3
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
7077197
handle
http://hdl.handle.net/1854/LU-7077197
date created
2016-02-09 09:58:15
date last changed
2016-12-21 15:42:31
@article{7077197,
  abstract     = {Remodeling refers to the development of specific but potentially irreversible structural changes in tissue. Caucasian eosinophilic chronic rhinosinusitis (CRS) with polyps associated or not with cystic fibrosis was discriminated by edema from CRS without nasal polyps, characterized by extensive fibrotic fields. However, changes in epithelial and extracellular matrix structures are common findings in all types of chronic inflammatory diseases of upper airways, but rarely specific and highly variable in extend. Recent studies have shown that remodeling in CRS appears to occur in parallel, rather than purely subsequent to inflammation. Furthermore, some preferential remodeling associations can be recognized. Tremendous efforts have been put in research on coagulation factors, cytokines, growth factors, and proteases supporting all phases of upper airway remodeling. The current exploration of other CRS sub-groups and of the particular link with concomitant asthma aims to optimize the classification of CRS and its staging modes and to develop novel therapies.},
  articleno    = {34},
  author       = {Watelet, Jean-Baptiste and Dogne, Jean-Michel and Mullier, Fran\c{c}ois},
  issn         = {1529-7322},
  journal      = {CURRENT ALLERGY AND ASTHMA REPORTS},
  keyword      = {MATRIX METALLOPROTEINASES,STAPHYLOCOCCUS-AUREUS,UPPER AIRWAYS,ALLERGIC RHINITIS,FIBRIN STRUCTURE,GROWTH-FACTOR,IN-VITRO,EXPRESSION,Chronic rhinosinusitis,Nasal polyps,Tissue remodeling,Tissue repair,NASAL POLYPS,FACTOR-XIII},
  language     = {eng},
  number       = {6},
  pages        = {7},
  title        = {Remodeling and repair in rhinosinusitis},
  url          = {http://dx.doi.org/10.1007/s11882-015-0531-3},
  volume       = {15},
  year         = {2015},
}

Chicago
Watelet, Jean-Baptiste, Jean-Michel Dogne, and François Mullier. 2015. “Remodeling and Repair in Rhinosinusitis.” Current Allergy and Asthma Reports 15 (6).
APA
Watelet, J.-B., Dogne, J.-M., & Mullier, F. (2015). Remodeling and repair in rhinosinusitis. CURRENT ALLERGY AND ASTHMA REPORTS, 15(6).
Vancouver
1.
Watelet J-B, Dogne J-M, Mullier F. Remodeling and repair in rhinosinusitis. CURRENT ALLERGY AND ASTHMA REPORTS. 2015;15(6).
MLA
Watelet, Jean-Baptiste, Jean-Michel Dogne, and François Mullier. “Remodeling and Repair in Rhinosinusitis.” CURRENT ALLERGY AND ASTHMA REPORTS 15.6 (2015): n. pag. Print.