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Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis

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Abstract
Systemic sclerosis is a connective tissue disease characterized by alterations in microvascular structure and function. In these patients, numerous studies have demonstrated a relationship between capillary morphology, and peripheral blood perfusion. Nailfold videocapillaroscopy reveals the peripheral microvascular morphology and thus allows classification and scoring of capillary abnormalities with respect to different microangiopathy patterns (early, active, and late). Laser Doppler flowmetry and laser speckle contrast analysis can be used to estimate cutaneous blood flow through microvessels and to assess and quantify blood perfusion at peripheral sites. These two methods are also used to identify changes in digital blood perfusion after the infusion of vasodilators.
Keywords
Peripheral blood perfusion, Laser speckle contrast analysis, PERIPHERAL-BLOOD PERFUSION, SPECKLE CONTRAST ANALYSIS, LASER-DOPPLER, NAILFOLD VIDEOCAPILLAROSCOPY, CAPILLAROSCOPIC ANALYSIS, RAYNAUDS-PHENOMENON, SCLERODERMA, ABNORMALITIES, RHEUMATOLOGY, DISEASE, Systemic sclerosis, Microvascular damage, Nailfold videocapillaroscopy

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Citation

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Chicago
Ruaro, Barbara, Vanessa Smith, Alberto Sulli, Saskia Decuman, Carmen Pizzorni, and Maurizio Cutolo. 2015. “Methods for the Morphological and Functional Evaluation of Microvascular Damage in Systemic Sclerosis.” Korean Journal of Internal Medicine 30 (1): 1–5.
APA
Ruaro, B., Smith, V., Sulli, A., Decuman, S., Pizzorni, C., & Cutolo, M. (2015). Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis. KOREAN JOURNAL OF INTERNAL MEDICINE, 30(1), 1–5.
Vancouver
1.
Ruaro B, Smith V, Sulli A, Decuman S, Pizzorni C, Cutolo M. Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis. KOREAN JOURNAL OF INTERNAL MEDICINE. 2015;30(1):1–5.
MLA
Ruaro, Barbara et al. “Methods for the Morphological and Functional Evaluation of Microvascular Damage in Systemic Sclerosis.” KOREAN JOURNAL OF INTERNAL MEDICINE 30.1 (2015): 1–5. Print.
@article{7061680,
  abstract     = {Systemic sclerosis is a connective tissue disease characterized by alterations in microvascular structure and function. In these patients, numerous studies have demonstrated a relationship between capillary morphology, and peripheral blood perfusion. Nailfold videocapillaroscopy reveals the peripheral microvascular morphology and thus allows classification and scoring of capillary abnormalities with respect to different microangiopathy patterns (early, active, and late). Laser Doppler flowmetry and laser speckle contrast analysis can be used to estimate cutaneous blood flow through microvessels and to assess and quantify blood perfusion at peripheral sites. These two methods are also used to identify changes in digital blood perfusion after the infusion of vasodilators.},
  author       = {Ruaro, Barbara and Smith, Vanessa and Sulli, Alberto and Decuman, Saskia and Pizzorni, Carmen and Cutolo, Maurizio},
  issn         = {1226-3303},
  journal      = {KOREAN JOURNAL OF INTERNAL MEDICINE},
  keywords     = {Peripheral blood perfusion,Laser speckle contrast analysis,PERIPHERAL-BLOOD PERFUSION,SPECKLE CONTRAST ANALYSIS,LASER-DOPPLER,NAILFOLD VIDEOCAPILLAROSCOPY,CAPILLAROSCOPIC ANALYSIS,RAYNAUDS-PHENOMENON,SCLERODERMA,ABNORMALITIES,RHEUMATOLOGY,DISEASE,Systemic sclerosis,Microvascular damage,Nailfold videocapillaroscopy},
  language     = {eng},
  number       = {1},
  pages        = {1--5},
  title        = {Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis},
  url          = {http://dx.doi.org/10.3904/kjim.2015.30.1.1},
  volume       = {30},
  year         = {2015},
}

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