Advanced search
1 file | 1.34 MB Add to list

Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour

Author
Organization
Abstract
Models of cardiac mechanics are increasingly used to investigate cardiac physiology. These models are characterized by a high level of complexity, including the particular anisotropic material properties of biological tissue and the actively contracting material. A large number of independent simulation codes have been developed, but a consistent way of verifying the accuracy and replicability of simulations is lacking. To aid in the verification of current and future cardiac mechanics solvers, this study provides three benchmark problems for cardiac mechanics. These benchmark problems test the ability to accurately simulate pressure-type forces that depend on the deformed objects geometry, anisotropic and spatially varying material properties similar to those seen in the left ventricle and active contractile forces. The benchmark was solved by 11 different groups to generate consensus solutions, with typical differences in higher-resolution solutions at approximately 0.5%, and consistent results between linear, quadratic and cubic finite elements as well as different approaches to simulating incompressible materials. Online tools and solutions are made available to allow these tests to be effectively used in verification of future cardiac mechanics software.
Keywords
cardiac mechanics, benchmark, verification, VVUQ, COMPUTATIONAL MODELS, LEFT-VENTRICLE, HUMAN HEART, MYOCARDIUM, TISSUE, ELECTROMECHANICS, DEFORMATIONS, FRAMEWORK, MOUSE

Downloads

  • Benchmark.pdf
    • full text
    • |
    • open access
    • |
    • PDF
    • |
    • 1.34 MB

Citation

Please use this url to cite or link to this publication:

MLA
Land, Sander et al. “Verification of Cardiac Mechanics Software: Benchmark Problems and Solutions for Testing Active and Passive Material Behaviour.” PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES 471.2184 (2015): n. pag. Print.
APA
Land, S., Gurev, V., Arens, S., Augustin, C. M., Baron, L., Blake, R., Bradley, C., et al. (2015). Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour. PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 471(2184).
Chicago author-date
Land, Sander, Viatcheslav Gurev, Sander Arens, Christoph M Augustin, Lukas Baron, Robert Blake, Chris Bradley, et al. 2015. “Verification of Cardiac Mechanics Software: Benchmark Problems and Solutions for Testing Active and Passive Material Behaviour.” Proceedings of the Royal Society A-mathematical Physical and Engineering Sciences 471 (2184).
Chicago author-date (all authors)
Land, Sander, Viatcheslav Gurev, Sander Arens, Christoph M Augustin, Lukas Baron, Robert Blake, Chris Bradley, Sebastian Castro, Andrew Crozier, Marco Favino, Thomas E Fastl, Thomas Fritz, Hao Gao, Alessio Gizzi, Boyce E Griffith, Daniel E Hurtado, Rolf Krause, Xiaoyu Luo, Martyn P Nash, Simone Pezzuto, Gernot Plank, Simone Rossi, Daniel Ruprecht, Gunnar Seemann, Nicolas P Smith, Joakim Sundnes, J Jeremy Rice, Natalia Trayanova, Dafang Wang, Zhinuo Jenny Wang, and Steven A Niederer. 2015. “Verification of Cardiac Mechanics Software: Benchmark Problems and Solutions for Testing Active and Passive Material Behaviour.” Proceedings of the Royal Society A-mathematical Physical and Engineering Sciences 471 (2184).
Vancouver
1.
Land S, Gurev V, Arens S, Augustin CM, Baron L, Blake R, et al. Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour. PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES. 2015;471(2184).
IEEE
[1]
S. Land et al., “Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour,” PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, vol. 471, no. 2184, 2015.
@article{7027757,
  abstract     = {Models of cardiac mechanics are increasingly used to investigate cardiac physiology. These models are characterized by a high level of complexity, including the particular anisotropic material   properties   of   biological   tissue   and   the   actively   contracting   material.   A   large number  of  independent  simulation  codes  have  been  developed,  but  a  consistent  way  of verifying  the  accuracy  and  replicability  of  simulations  is  lacking.  To  aid  in  the  verification of  current  and  future  cardiac  mechanics  solvers,  this  study  provides  three  benchmark problems  for  cardiac  mechanics.  These  benchmark  problems  test  the  ability  to  accurately simulate  pressure-type  forces  that  depend  on  the  deformed  objects  geometry,  anisotropic and  spatially  varying  material  properties  similar  to  those  seen  in  the  left  ventricle  and active  contractile  forces.  The  benchmark  was  solved  by  11  different  groups  to  generate consensus solutions, with typical differences in higher-resolution solutions at approximately 0.5%,  and  consistent  results  between  linear,  quadratic  and  cubic  finite  elements  as  well  as different approaches to simulating incompressible materials. Online tools and solutions are made  available  to  allow  these  tests  to  be  effectively  used  in  verification  of  future  cardiac mechanics software.},
  articleno    = {20150641},
  author       = {Land, Sander and Gurev, Viatcheslav and Arens, Sander and Augustin, Christoph M and Baron, Lukas and Blake, Robert and Bradley, Chris and Castro, Sebastian and Crozier, Andrew and Favino, Marco and Fastl, Thomas E and Fritz, Thomas and Gao, Hao and Gizzi, Alessio and Griffith, Boyce E and Hurtado, Daniel E and Krause, Rolf and Luo, Xiaoyu and Nash, Martyn P and Pezzuto, Simone and Plank, Gernot and Rossi, Simone and Ruprecht, Daniel and Seemann, Gunnar and Smith, Nicolas P and Sundnes, Joakim and Rice, J Jeremy and Trayanova, Natalia and Wang, Dafang and Jenny Wang, Zhinuo and Niederer, Steven A},
  issn         = {1364-5021},
  journal      = {PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES},
  keywords     = {cardiac mechanics,benchmark,verification,VVUQ,COMPUTATIONAL MODELS,LEFT-VENTRICLE,HUMAN HEART,MYOCARDIUM,TISSUE,ELECTROMECHANICS,DEFORMATIONS,FRAMEWORK,MOUSE},
  language     = {eng},
  number       = {2184},
  pages        = {20},
  title        = {Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour},
  url          = {http://dx.doi.org/10.1098/rspa.2015.0641},
  volume       = {471},
  year         = {2015},
}

Altmetric
View in Altmetric
Web of Science
Times cited: