Advanced search
Add to list

Estimation of canine Leishmania infection prevalence in six cities of the Algerian littoral zone using a Bayesian approach

(2015) PLOS ONE. 10(3).
Author
Organization
Abstract
A large-scale study on canine Leishmania infection (CanL) was conducted in six localities along a west-east transect in the Algerian littoral zone (Tlemcen, Mostaganem, Tipaza, Boumerdes, Bejaia, Jijel) and covering two sampling periods. In total 2,184 dogs were tested with an indirect fluorescent antibody test (IFAT) and a direct agglutination test (DAT). Combined multiple-testing and several statistical methods were compared to estimate the CanL true prevalence and tests characteristics (sensitivity and specificity). The Bayesian full model showed the best fit and yielded prevalence estimates between 11% (Mostaganem, first period) and 38% (Bejaia, second period). Sensitivity of IFAT varied (in function of locality) between 86% and 88% while its specificity varied between 65% and 87%. DAT was less sensitive than IFAT but showed a higher specificity (between 80% and 95% in function of locality or/and season). A general increasing trend of the CanL prevalence was noted from west to east. A concordance between the present results and the incidence of human cases of visceral leishmaniasis was observed, where also a maximum was recorded for Bejaia. The results of the present study highlight the dangers when using IFAT as a gold standard.
Keywords
DIRECT AGGLUTINATION-TEST, VISCERAL LEISHMANIASIS, DIAGNOSTIC-TESTS, INFANTUM INFECTION, PHLEBOTOMUS-PERNICIOSUS, CUTANEOUS LEISHMANIASIS, CONDITIONAL DEPENDENCE, DISEASE PREVALENCE, SOUTHERN SPAIN, DOGS

Citation

Please use this url to cite or link to this publication:

MLA
Adel, Amel et al. “Estimation of Canine Leishmania Infection Prevalence in Six Cities of the Algerian Littoral Zone Using a Bayesian Approach.” PLOS ONE 10.3 (2015): n. pag. Print.
APA
Adel, A., Abatih, E., Speybroeck, N., Soukehal, A., Bouguedour, R., Boughalem, K., Bouhbal, A., et al. (2015). Estimation of canine Leishmania infection prevalence in six cities of the Algerian littoral zone using a Bayesian approach. PLOS ONE, 10(3).
Chicago author-date
Adel, Amel, Emmanuel Abatih, Niko Speybroeck, Abdelkrim Soukehal, Rachid Bouguedour, Karim Boughalem, Abdelmalek Bouhbal, Mouloud Djerbal, Claude Saegerman, and Dirk Berkvens. 2015. “Estimation of Canine Leishmania Infection Prevalence in Six Cities of the Algerian Littoral Zone Using a Bayesian Approach.” Plos One 10 (3).
Chicago author-date (all authors)
Adel, Amel, Emmanuel Abatih, Niko Speybroeck, Abdelkrim Soukehal, Rachid Bouguedour, Karim Boughalem, Abdelmalek Bouhbal, Mouloud Djerbal, Claude Saegerman, and Dirk Berkvens. 2015. “Estimation of Canine Leishmania Infection Prevalence in Six Cities of the Algerian Littoral Zone Using a Bayesian Approach.” Plos One 10 (3).
Vancouver
1.
Adel A, Abatih E, Speybroeck N, Soukehal A, Bouguedour R, Boughalem K, et al. Estimation of canine Leishmania infection prevalence in six cities of the Algerian littoral zone using a Bayesian approach. PLOS ONE. 2015;10(3).
IEEE
[1]
A. Adel et al., “Estimation of canine Leishmania infection prevalence in six cities of the Algerian littoral zone using a Bayesian approach,” PLOS ONE, vol. 10, no. 3, 2015.
@article{6992329,
  abstract     = {A large-scale study on canine Leishmania infection (CanL) was conducted in six localities along a west-east transect in the Algerian littoral zone (Tlemcen, Mostaganem, Tipaza, Boumerdes, Bejaia, Jijel) and covering two sampling periods. In total 2,184 dogs were tested with an indirect fluorescent antibody test (IFAT) and a direct agglutination test (DAT). Combined multiple-testing and several statistical methods were compared to estimate the CanL true prevalence and tests characteristics (sensitivity and specificity). The Bayesian full model showed the best fit and yielded prevalence estimates between 11% (Mostaganem, first period) and 38% (Bejaia, second period). Sensitivity of IFAT varied (in function of locality) between 86% and 88% while its specificity varied between 65% and 87%. DAT was less sensitive than IFAT but showed a higher specificity (between 80% and 95% in function of locality or/and season). A general increasing trend of the CanL prevalence was noted from west to east. A concordance between the present results and the incidence of human cases of visceral leishmaniasis was observed, where also a maximum was recorded for Bejaia. The results of the present study highlight the dangers when using IFAT as a gold standard.},
  articleno    = {e0117313},
  author       = {Adel, Amel and Abatih, Emmanuel and Speybroeck, Niko and Soukehal, Abdelkrim and Bouguedour, Rachid and Boughalem, Karim and Bouhbal, Abdelmalek and Djerbal, Mouloud and Saegerman, Claude and Berkvens, Dirk},
  issn         = {1932-6203},
  journal      = {PLOS ONE},
  keywords     = {DIRECT AGGLUTINATION-TEST,VISCERAL LEISHMANIASIS,DIAGNOSTIC-TESTS,INFANTUM INFECTION,PHLEBOTOMUS-PERNICIOSUS,CUTANEOUS LEISHMANIASIS,CONDITIONAL DEPENDENCE,DISEASE PREVALENCE,SOUTHERN SPAIN,DOGS},
  language     = {eng},
  number       = {3},
  pages        = {17},
  title        = {Estimation of canine Leishmania infection prevalence in six cities of the Algerian littoral zone using a Bayesian approach},
  url          = {http://dx.doi.org/10.1371/journal.pone.0117313},
  volume       = {10},
  year         = {2015},
}

Altmetric
View in Altmetric
Web of Science
Times cited: