Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering
- Author
- Dieter Blancquaert (UGent) , Jeroen Van Daele (UGent) , Simon Strobbe (UGent) , Filip Kiekens (UGent) , Serguei Storojenko (UGent) , Hans De Steur (UGent) , Xavier Gellynck (UGent) , Willy Lambert (UGent) , Christophe Stove (UGent) and Dominique Van Der Straeten (UGent)
- Organization
- Abstract
- Biofortification of staple crops could help to alleviate micronutrient deficiencies in humans. We show that folates in stored rice grains are unstable, which reduces the potential benefits of folate biofortification. We obtain folate concentrations that are up to 150 fold higher than those of wild-type rice by complexing folate to folate-binding proteins to improve folate stability, thereby enabling long-term storage of biofortified high-folate rice grains.
- Keywords
- EXPRESSION, HEALTH, FOLIC-ACID, TIME QUANTITATIVE PCR, IMPACT, GENES, ENHANCEMENT, FRAMEWORK, SEQUENCE, CHINA
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-6971030
- MLA
- Blancquaert, Dieter, et al. “Improving Folate (Vitamin B-9) Stability in Biofortified Rice through Metabolic Engineering.” NATURE BIOTECHNOLOGY, vol. 33, no. 10, 2015, pp. 1076–78, doi:10.1038/nbt.3358.
- APA
- Blancquaert, D., Van Daele, J., Strobbe, S., Kiekens, F., Storojenko, S., De Steur, H., … Van Der Straeten, D. (2015). Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering. NATURE BIOTECHNOLOGY, 33(10), 1076–1078. https://doi.org/10.1038/nbt.3358
- Chicago author-date
- Blancquaert, Dieter, Jeroen Van Daele, Simon Strobbe, Filip Kiekens, Serguei Storojenko, Hans De Steur, Xavier Gellynck, Willy Lambert, Christophe Stove, and Dominique Van Der Straeten. 2015. “Improving Folate (Vitamin B-9) Stability in Biofortified Rice through Metabolic Engineering.” NATURE BIOTECHNOLOGY 33 (10): 1076–78. https://doi.org/10.1038/nbt.3358.
- Chicago author-date (all authors)
- Blancquaert, Dieter, Jeroen Van Daele, Simon Strobbe, Filip Kiekens, Serguei Storojenko, Hans De Steur, Xavier Gellynck, Willy Lambert, Christophe Stove, and Dominique Van Der Straeten. 2015. “Improving Folate (Vitamin B-9) Stability in Biofortified Rice through Metabolic Engineering.” NATURE BIOTECHNOLOGY 33 (10): 1076–1078. doi:10.1038/nbt.3358.
- Vancouver
- 1.Blancquaert D, Van Daele J, Strobbe S, Kiekens F, Storojenko S, De Steur H, et al. Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering. NATURE BIOTECHNOLOGY. 2015;33(10):1076–8.
- IEEE
- [1]D. Blancquaert et al., “Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering,” NATURE BIOTECHNOLOGY, vol. 33, no. 10, pp. 1076–1078, 2015.
@article{6971030,
abstract = {{Biofortification of staple crops could help to alleviate micronutrient deficiencies in humans. We show that folates in stored rice grains are unstable, which reduces the potential benefits of folate biofortification. We obtain folate concentrations that are up to 150 fold higher than those of wild-type rice by complexing folate to folate-binding proteins to improve folate stability, thereby enabling long-term storage of biofortified high-folate rice grains.}},
author = {{Blancquaert, Dieter and Van Daele, Jeroen and Strobbe, Simon and Kiekens, Filip and Storojenko, Serguei and De Steur, Hans and Gellynck, Xavier and Lambert, Willy and Stove, Christophe and Van Der Straeten, Dominique}},
issn = {{1087-0156}},
journal = {{NATURE BIOTECHNOLOGY}},
keywords = {{EXPRESSION,HEALTH,FOLIC-ACID,TIME QUANTITATIVE PCR,IMPACT,GENES,ENHANCEMENT,FRAMEWORK,SEQUENCE,CHINA}},
language = {{eng}},
number = {{10}},
pages = {{1076--1078}},
title = {{Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering}},
url = {{http://dx.doi.org/10.1038/nbt.3358}},
volume = {{33}},
year = {{2015}},
}
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