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Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering

Dieter Blancquaert (UGent) , Jeroen Van Daele (UGent) , Simon Strobbe (UGent) , Filip Kiekens (UGent) , Serguei Storojenko (UGent) , Hans De Steur (UGent) , Xavier Gellynck (UGent) , Willy Lambert (UGent) , Christophe Stove (UGent) and Dominique Van Der Straeten (UGent)
(2015) NATURE BIOTECHNOLOGY. 33(10). p.1076-1078
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Abstract
Biofortification of staple crops could help to alleviate micronutrient deficiencies in humans. We show that folates in stored rice grains are unstable, which reduces the potential benefits of folate biofortification. We obtain folate concentrations that are up to 150 fold higher than those of wild-type rice by complexing folate to folate-binding proteins to improve folate stability, thereby enabling long-term storage of biofortified high-folate rice grains.
Keywords
EXPRESSION, HEALTH, FOLIC-ACID, TIME QUANTITATIVE PCR, IMPACT, GENES, ENHANCEMENT, FRAMEWORK, SEQUENCE, CHINA

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Citation

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Chicago
Blancquaert, Dieter, Jeroen Van Daele, Simon Strobbe, Filip Kiekens, Serguei Storojenko, Hans De Steur, Xavier Gellynck, Willy Lambert, Christophe Stove, and Dominique Van Der Straeten. 2015. “Improving Folate (vitamin B-9) Stability in Biofortified Rice Through Metabolic Engineering.” Nature Biotechnology 33 (10): 1076–1078.
APA
Blancquaert, D., Van Daele, J., Strobbe, S., Kiekens, F., Storojenko, S., De Steur, H., Gellynck, X., et al. (2015). Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering. NATURE BIOTECHNOLOGY, 33(10), 1076–1078.
Vancouver
1.
Blancquaert D, Van Daele J, Strobbe S, Kiekens F, Storojenko S, De Steur H, et al. Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering. NATURE BIOTECHNOLOGY. 2015;33(10):1076–8.
MLA
Blancquaert, Dieter, Jeroen Van Daele, Simon Strobbe, et al. “Improving Folate (vitamin B-9) Stability in Biofortified Rice Through Metabolic Engineering.” NATURE BIOTECHNOLOGY 33.10 (2015): 1076–1078. Print.
@article{6971030,
  abstract     = {Biofortification of staple crops could help to alleviate micronutrient deficiencies in humans. We show that folates in stored rice grains are unstable, which reduces the potential benefits of folate biofortification. We obtain folate concentrations that are up to 150 fold higher than those of wild-type rice by complexing folate to folate-binding proteins to improve folate stability, thereby enabling long-term storage of biofortified high-folate rice grains.},
  author       = {Blancquaert, Dieter and Van Daele, Jeroen and Strobbe, Simon and Kiekens, Filip and Storojenko, Serguei and De Steur, Hans and Gellynck, Xavier and Lambert, Willy and Stove, Christophe and Van Der Straeten, Dominique},
  issn         = {1087-0156},
  journal      = {NATURE BIOTECHNOLOGY},
  keyword      = {EXPRESSION,HEALTH,FOLIC-ACID,TIME QUANTITATIVE PCR,IMPACT,GENES,ENHANCEMENT,FRAMEWORK,SEQUENCE,CHINA},
  language     = {eng},
  number       = {10},
  pages        = {1076--1078},
  title        = {Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering},
  url          = {http://dx.doi.org/10.1038/nbt.3358},
  volume       = {33},
  year         = {2015},
}

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