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Abstract
The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, otolaryngological, locomotor, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in over 1200 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.
Keywords
Biomarkers, Cardiovascular diseases, Renal diseases, Psychiatric diseases, Respiratory diseases, GENOME-WIDE ASSOCIATION, CORONARY-HEART-DISEASE, POPULATION-BASED COHORT, C-REACTIVE PROTEIN, NONALCOHOLIC FATTY LIVER, SMALL VESSEL DISEASE, ALL-CAUSE MORTALITY, OBSTRUCTIVE PULMONARY-DISEASE, SUDDEN CARDIAC DEATH, NET RECLASSIFICATION IMPROVEMENT, Neurological diseases, Oncology, Ophthalmic diseases, Otolaryngological diseases, Pharmacoepidemiology, Liver diseases, Genetic epidemiology, Epidemiologic methods, Endocrine diseases, Cohort study, Dermatological diseases

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Chicago
Hofman, Albert, Guy Brusselle, Sarwa Darwish Murad, Cornelia M van Duijn, Oscar H Franco, André Goedegebure, M Arfan Ikram, et al. 2015. “The Rotterdam Study : 2016 Objectives and Design Update.” European Journal of Epidemiology 30 (8): 661–708.
APA
Hofman, A., Brusselle, G., Murad, S. D., van Duijn, C. M., Franco, O. H., Goedegebure, A., Ikram, M. A., et al. (2015). The Rotterdam Study : 2016 objectives and design update. EUROPEAN JOURNAL OF EPIDEMIOLOGY, 30(8), 661–708.
Vancouver
1.
Hofman A, Brusselle G, Murad SD, van Duijn CM, Franco OH, Goedegebure A, et al. The Rotterdam Study : 2016 objectives and design update. EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2015;30(8):661–708.
MLA
Hofman, Albert, Guy Brusselle, Sarwa Darwish Murad, et al. “The Rotterdam Study : 2016 Objectives and Design Update.” EUROPEAN JOURNAL OF EPIDEMIOLOGY 30.8 (2015): 661–708. Print.
@article{6965037,
  abstract     = {The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, otolaryngological, locomotor, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in over 1200 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.},
  author       = {Hofman, Albert and Brusselle, Guy and Murad, Sarwa Darwish and van Duijn, Cornelia M and Franco, Oscar H and Goedegebure, Andr{\'e} and Ikram, M Arfan and Klaver, Caroline CW and Nijsten, Tamar EC and Peeters, Robin P and Stricker, Bruno H Ch and Tiemeier, Henning W and Uitterlinden, Andr{\'e} G and Vernooij, Meike W},
  issn         = {0393-2990},
  journal      = {EUROPEAN JOURNAL OF EPIDEMIOLOGY},
  language     = {eng},
  number       = {8},
  pages        = {661--708},
  title        = {The Rotterdam Study : 2016 objectives and design update},
  url          = {http://dx.doi.org/10.1007/s10654-015-0082-x},
  volume       = {30},
  year         = {2015},
}

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