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microRNAs in colon cancer : a roadmap for discovery

(2012) FEBS LETTERS. 586(19). p.3000-3007
Author
Organization
Abstract
Cancer omics data are exponentially created and associated with clinical variables, and important findings can be extracted based on bioinformatics approaches which can then be experimentally validated. Many of these findings are related to a specific class of non-coding RNA molecules called microRNAs (miRNAs) (post-transcriptional regulators of mRNA expression). The related research field is quite heterogeneous and bioinformaticians, clinicians, statisticians and biologists, as well as data miners and engineers collaborate to cure stored data and on new impulses coming from the output of the latest Next Generation Sequencing technologies. Here we review the main research findings on miRNA of the first 10 years in colon cancer research with an emphasis on possible uses in clinical practice. This review intends to provide a road map in the jungle of publications of miRNA in colorectal cancer, focusing on data availability and new ways to generate biologically relevant information out of these huge amounts of data.
Keywords
CELL LUNG-CANCER, COLORECTAL-CANCER, Personalized medicine, Colon cancer, microRNA, Omic, TUMOR-SUPPRESSOR, DOWN-REGULATION, POOR-PROGNOSIS, NONCODING RNA, STAGE-II, EXPRESSION, GENE, GROWTH

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Citation

Please use this url to cite or link to this publication:

MLA
Rossi, Simona et al. “microRNAs in Colon Cancer : a Roadmap for Discovery.” FEBS LETTERS 586.19 (2012): 3000–3007. Print.
APA
Rossi, S., Di Narzo, A. F., Mestdagh, P., Jacobs, B., Bosman, F. T., Gustavsson, B., Majoie, B., et al. (2012). microRNAs in colon cancer : a roadmap for discovery. FEBS LETTERS, 586(19), 3000–3007.
Chicago author-date
Rossi, Simona, Antonio Fabio Di Narzo, Pieter Mestdagh, Bart Jacobs, Fredrik T Bosman, Bengt Gustavsson, Bernard Majoie, et al. 2012. “microRNAs in Colon Cancer : a Roadmap for Discovery.” Febs Letters 586 (19): 3000–3007.
Chicago author-date (all authors)
Rossi, Simona, Antonio Fabio Di Narzo, Pieter Mestdagh, Bart Jacobs, Fredrik T Bosman, Bengt Gustavsson, Bernard Majoie, Arnaud Roth, Jo Vandesompele, Isidore Rigoutsos, Mauro Delorenzi, and Sabine Tejpar. 2012. “microRNAs in Colon Cancer : a Roadmap for Discovery.” Febs Letters 586 (19): 3000–3007.
Vancouver
1.
Rossi S, Di Narzo AF, Mestdagh P, Jacobs B, Bosman FT, Gustavsson B, et al. microRNAs in colon cancer : a roadmap for discovery. FEBS LETTERS. 2012;586(19):3000–7.
IEEE
[1]
S. Rossi et al., “microRNAs in colon cancer : a roadmap for discovery,” FEBS LETTERS, vol. 586, no. 19, pp. 3000–3007, 2012.
@article{6913631,
  abstract     = {Cancer omics data are exponentially created and associated with clinical variables, and important findings can be extracted based on bioinformatics approaches which can then be experimentally validated. Many of these findings are related to a specific class of non-coding RNA molecules called microRNAs (miRNAs) (post-transcriptional regulators of mRNA expression). The related research field is quite heterogeneous and bioinformaticians, clinicians, statisticians and biologists, as well as data miners and engineers collaborate to cure stored data and on new impulses coming from the output of the latest Next Generation Sequencing technologies. 
Here we review the main research findings on miRNA of the first 10 years in colon cancer research with an emphasis on possible uses in clinical practice. This review intends to provide a road map in the jungle of publications of miRNA in colorectal cancer, focusing on data availability and new ways to generate biologically relevant information out of these huge amounts of data.},
  author       = {Rossi, Simona and Di Narzo, Antonio Fabio and Mestdagh, Pieter and Jacobs, Bart and Bosman, Fredrik T and Gustavsson, Bengt and Majoie, Bernard and Roth, Arnaud and Vandesompele, Jo and Rigoutsos, Isidore and Delorenzi, Mauro and Tejpar, Sabine},
  issn         = {0014-5793},
  journal      = {FEBS LETTERS},
  keywords     = {CELL LUNG-CANCER,COLORECTAL-CANCER,Personalized medicine,Colon cancer,microRNA,Omic,TUMOR-SUPPRESSOR,DOWN-REGULATION,POOR-PROGNOSIS,NONCODING RNA,STAGE-II,EXPRESSION,GENE,GROWTH},
  language     = {eng},
  number       = {19},
  pages        = {3000--3007},
  title        = {microRNAs in colon cancer : a roadmap for discovery},
  url          = {http://dx.doi.org/10.1016/j.febslet.2012.07.048},
  volume       = {586},
  year         = {2012},
}

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