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Organ doses and radiation risk of computed tomographic coronary angiography in a clinical patient population: how do low-dose acquisition modes compare?

Liesbeth Eloot (UGent) , Daniel Devos (UGent) , STEPHEN VAN MEERBEECK (UGent) , Eric Achten (UGent) , Koenraad Verstraete (UGent) , Hubert Thierens (UGent) and Klaus Bacher (UGent)
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Abstract
Objective : To compare the organ doses and lifetime-attributable risk of cancer for electrocardiogram-triggered sequential and high-pitch helical scanning in a clinical patient population. Methods : Phantom thermoluminiscence dosimeter measurements were used as a model for the organ dose assessment of 314 individual patients who underwent coronary computed tomographic angiography. Patient-specific lifetime-attributable cancer risks were calculated. Results : Phantom measurements showed that heart rate had a significant influence on the delivered radiation exposure in sequential mode, and calcium scoring and contrast bolus tracking scans make a nonnegligible contribution to patients' dose. Therefore, they should be taken into account for patients' organ dose estimations. Median cancer induction risks are low, with 0.008% (0.0016%) and 0.022% (0.056%) for high-pitch and sequential scanning for men (women), respectively. Conclusions : The use of high-pitch helical scanning leads to 65% and 72% lower lifetime-attributable risk values for men and women, respectively, compared with sequential scanning.
Keywords
REDUCTION, CHILDHOOD, CHALLENGES, MULTICENTER, PITCH, EXPOSURE, CANCER-RISK, CARDIAC CT, IMAGE QUALITY, CT ANGIOGRAPHY

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MLA
Eloot, Liesbeth et al. “Organ Doses and Radiation Risk of Computed Tomographic Coronary Angiography in a Clinical Patient Population: How Do Low-dose Acquisition Modes Compare?” JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 39.4 (2015): 591–597. Print.
APA
Eloot, L., Devos, D., VAN MEERBEECK, S., Achten, E., Verstraete, K., Thierens, H., & Bacher, K. (2015). Organ doses and radiation risk of computed tomographic coronary angiography in a clinical patient population: how do low-dose acquisition modes compare? JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 39(4), 591–597.
Chicago author-date
Eloot, Liesbeth, Daniel Devos, STEPHEN VAN MEERBEECK, Eric Achten, Koenraad Verstraete, Hubert Thierens, and Klaus Bacher. 2015. “Organ Doses and Radiation Risk of Computed Tomographic Coronary Angiography in a Clinical Patient Population: How Do Low-dose Acquisition Modes Compare?” Journal of Computer Assisted Tomography 39 (4): 591–597.
Chicago author-date (all authors)
Eloot, Liesbeth, Daniel Devos, STEPHEN VAN MEERBEECK, Eric Achten, Koenraad Verstraete, Hubert Thierens, and Klaus Bacher. 2015. “Organ Doses and Radiation Risk of Computed Tomographic Coronary Angiography in a Clinical Patient Population: How Do Low-dose Acquisition Modes Compare?” Journal of Computer Assisted Tomography 39 (4): 591–597.
Vancouver
1.
Eloot L, Devos D, VAN MEERBEECK S, Achten E, Verstraete K, Thierens H, et al. Organ doses and radiation risk of computed tomographic coronary angiography in a clinical patient population: how do low-dose acquisition modes compare? JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY. 2015;39(4):591–7.
IEEE
[1]
L. Eloot et al., “Organ doses and radiation risk of computed tomographic coronary angiography in a clinical patient population: how do low-dose acquisition modes compare?,” JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, vol. 39, no. 4, pp. 591–597, 2015.
@article{6909392,
  abstract     = {Objective : To compare the organ doses and lifetime-attributable risk of cancer for electrocardiogram-triggered sequential and high-pitch helical scanning in a clinical patient population. 
Methods : Phantom thermoluminiscence dosimeter measurements were used as a model for the organ dose assessment of 314 individual patients who underwent coronary computed tomographic angiography. Patient-specific lifetime-attributable cancer risks were calculated. 
Results : Phantom measurements showed that heart rate had a significant influence on the delivered radiation exposure in sequential mode, and calcium scoring and contrast bolus tracking scans make a nonnegligible contribution to patients' dose. Therefore, they should be taken into account for patients' organ dose estimations. Median cancer induction risks are low, with 0.008% (0.0016%) and 0.022% (0.056%) for high-pitch and sequential scanning for men (women), respectively. 
Conclusions : The use of high-pitch helical scanning leads to 65% and 72% lower lifetime-attributable risk values for men and women, respectively, compared with sequential scanning.},
  author       = {Eloot, Liesbeth and Devos, Daniel and VAN MEERBEECK, STEPHEN and Achten, Eric and Verstraete, Koenraad and Thierens, Hubert and Bacher, Klaus},
  issn         = {0363-8715},
  journal      = {JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY},
  keywords     = {REDUCTION,CHILDHOOD,CHALLENGES,MULTICENTER,PITCH,EXPOSURE,CANCER-RISK,CARDIAC CT,IMAGE QUALITY,CT ANGIOGRAPHY},
  language     = {eng},
  number       = {4},
  pages        = {591--597},
  title        = {Organ doses and radiation risk of computed tomographic coronary angiography in a clinical patient population: how do low-dose acquisition modes compare?},
  url          = {http://dx.doi.org/10.1097/RCT.0000000000000253},
  volume       = {39},
  year         = {2015},
}

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