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Radiologic evaluation of compressive osseointegration for the fixation of reconstruction prostheses after tumor resection

Manol Lazarov (UGent) , THOMAS DE BO (UGent) , Bart Poffyn (UGent) and Gwen Sys (UGent)
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Organization
Abstract
Objective. In pursuance of thoroughly understanding and facilitating the evaluation of the radiological changes in the preloaded bone by Compliant Pre-Stress osseointegration (Compress Biomet, Warsaw, Indiana) a new staging method was created depicting four stages. Methods. Two cohorts (10 and 17 patients resp., not-receiving and receiving chemotherapy) were compared in terms of progression of osseointegration. Based on the changes at the bone-metal interface seen on rontgenorgrams four stages were defined: stage 0: immediate postoperative status, no ingrowth, or noncalcified callus; stage 1: early mineralization, calcified callus; stage 2: mature mineralization; and stage 3: hypertrophy at the level of the pins. Results. "there were no significant differences between the two cohorts. Group 2, which was significantly younger than group 1 (p < 0.001), presented a delayed initial rate of bone formation and reached stage 1 at 6 months instead of 3 months like group 1. The children from the group 2 demonstrated a visible rebound ingrowth. Conclusion. Despite the fact that the staging fails to demonstrate a statistical difference, it is rather simple and can be used for future studies.
Keywords
REPLACEMENTS, FAILURE, CHEMOTHERAPY, BONE, ENDOPROSTHESES

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Please use this url to cite or link to this publication:

MLA
Lazarov, Manol et al. “Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses After Tumor Resection.” BIOMED RESEARCH INTERNATIONAL (2015): n. pag. Print.
APA
Lazarov, M., DE BO, T., Poffyn, B., & Sys, G. (2015). Radiologic evaluation of compressive osseointegration for the fixation of reconstruction prostheses after tumor resection. BIOMED RESEARCH INTERNATIONAL.
Chicago author-date
Lazarov, Manol, THOMAS DE BO, Bart Poffyn, and Gwen Sys. 2015. “Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses After Tumor Resection.” Biomed Research International.
Chicago author-date (all authors)
Lazarov, Manol, THOMAS DE BO, Bart Poffyn, and Gwen Sys. 2015. “Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses After Tumor Resection.” Biomed Research International.
Vancouver
1.
Lazarov M, DE BO T, Poffyn B, Sys G. Radiologic evaluation of compressive osseointegration for the fixation of reconstruction prostheses after tumor resection. BIOMED RESEARCH INTERNATIONAL. 2015;
IEEE
[1]
M. Lazarov, T. DE BO, B. Poffyn, and G. Sys, “Radiologic evaluation of compressive osseointegration for the fixation of reconstruction prostheses after tumor resection,” BIOMED RESEARCH INTERNATIONAL, 2015.
@article{6884671,
  abstract     = {Objective. In pursuance of thoroughly understanding and facilitating the evaluation of the radiological changes in the preloaded bone by Compliant Pre-Stress osseointegration (Compress Biomet, Warsaw, Indiana) a new staging method was created depicting four stages.
Methods. Two cohorts (10 and 17 patients resp., not-receiving and receiving chemotherapy) were compared in terms of progression of osseointegration. Based on the changes at the bone-metal interface seen on rontgenorgrams four stages were defined: stage 0: immediate postoperative status, no ingrowth, or noncalcified callus; stage 1: early mineralization, calcified callus; stage 2: mature mineralization; and stage 3: hypertrophy at the level of the pins.
Results. "there were no significant differences between the two cohorts. Group 2, which was significantly younger than group 1 (p < 0.001), presented a delayed initial rate of bone formation and reached stage 1 at 6 months instead of 3 months like group 1. The children from the group 2 demonstrated a visible rebound ingrowth.
Conclusion. Despite the fact that the staging fails to demonstrate a statistical difference, it is rather simple and can be used for future studies.},
  articleno    = {513939},
  author       = {Lazarov, Manol and DE BO, THOMAS and Poffyn, Bart and Sys, Gwen},
  issn         = {2314-6133},
  journal      = {BIOMED RESEARCH INTERNATIONAL},
  keywords     = {REPLACEMENTS,FAILURE,CHEMOTHERAPY,BONE,ENDOPROSTHESES},
  language     = {eng},
  pages        = {7},
  title        = {Radiologic evaluation of compressive osseointegration for the fixation of reconstruction prostheses after tumor resection},
  url          = {http://dx.doi.org/10.1155/2015/513939},
  year         = {2015},
}

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