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Oxidative post-translational modifications of cysteine residues in plant signal transduction

(2015) JOURNAL OF EXPERIMENTAL BOTANY. 66(10). p.2923-2934
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Biotechnology for a sustainable economy (Bio-Economy)
Abstract
In plants, fluctuation of the redox balance by altered levels of reactive oxygen species (ROS) can affect many aspects of cellular physiology. ROS homeostasis is governed by a diversified set of antioxidant systems. Perturbation of this homeostasis leads to transient or permanent changes in the redox status and is exploited by plants in different stress signalling mechanisms. Understanding how plants sense ROS and transduce these stimuli into downstream biological responses is still a major challenge. ROS can provoke reversible and irreversible modifications to proteins that act in diverse signalling pathways. These oxidative post-translational modifications (Ox-PTMs) lead to oxidative damage and/or trigger structural alterations in these target proteins. Characterization of the effect of individual Ox-PTMs on individual proteins is the key to a better understanding of how cells interpret the oxidative signals that arise from developmental cues and stress conditions. This review focuses on ROS-mediated Ox-PTMs on cysteine (Cys) residues. The Cys side chain, with its high nucleophilic capacity, appears to be the principle target of ROS. Ox-PTMs on Cys residues participate in various signalling cascades initiated by plant stress hormones. We review the mechanistic aspects and functional consequences of Cys Ox-PTMs on specific target proteins in view of stress signalling events.
Keywords
NADPH OXIDASE, NITRIC-OXIDE, MAP KINASE, REDOX REGULATION, HYDROGEN-PEROXIDE, ARABIDOPSIS-THALIANA, OSMPK6 IN-VITRO, ABSCISIC-ACID, ANION CHANNEL SLAH3, ACTIVATED PROTEIN-KINASE, signal perception, reactive oxygen species, redox regulation, phytohormone signalling, oxidative stress, Cysteine oxidative post-translational modifications

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Citation

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Chicago
Waszczak, Cezary, Mosammat Salma Akter, Silke Jacques, Jingjing Huang, Joris Messens, and Frank Van Breusegem. 2015. “Oxidative Post-translational Modifications of Cysteine Residues in Plant Signal Transduction.” Journal of Experimental Botany 66 (10): 2923–2934.
APA
Waszczak, C., Akter, M. S., Jacques, S., Huang, J., Messens, J., & Van Breusegem, F. (2015). Oxidative post-translational modifications of cysteine residues in plant signal transduction. JOURNAL OF EXPERIMENTAL BOTANY, 66(10), 2923–2934.
Vancouver
1.
Waszczak C, Akter MS, Jacques S, Huang J, Messens J, Van Breusegem F. Oxidative post-translational modifications of cysteine residues in plant signal transduction. JOURNAL OF EXPERIMENTAL BOTANY. 2015;66(10):2923–34.
MLA
Waszczak, Cezary, Mosammat Salma Akter, Silke Jacques, et al. “Oxidative Post-translational Modifications of Cysteine Residues in Plant Signal Transduction.” JOURNAL OF EXPERIMENTAL BOTANY 66.10 (2015): 2923–2934. Print.
@article{6864419,
  abstract     = {In plants, fluctuation of the redox balance by altered levels of reactive oxygen species (ROS) can affect many aspects of cellular physiology. ROS homeostasis is governed by a diversified set of antioxidant systems. Perturbation of this homeostasis leads to transient or permanent changes in the redox status and is exploited by plants in different stress signalling mechanisms. Understanding how plants sense ROS and transduce these stimuli into downstream biological responses is still a major challenge. ROS can provoke reversible and irreversible modifications to proteins that act in diverse signalling pathways. These oxidative post-translational modifications (Ox-PTMs) lead to oxidative damage and/or trigger structural alterations in these target proteins. Characterization of the effect of individual Ox-PTMs on individual proteins is the key to a better understanding of how cells interpret the oxidative signals that arise from developmental cues and stress conditions. This review focuses on ROS-mediated Ox-PTMs on cysteine (Cys) residues. The Cys side chain, with its high nucleophilic capacity, appears to be the principle target of ROS. Ox-PTMs on Cys residues participate in various signalling cascades initiated by plant stress hormones. We review the mechanistic aspects and functional consequences of Cys Ox-PTMs on specific target proteins in view of stress signalling events.},
  author       = {Waszczak, Cezary and Akter, Mosammat Salma and Jacques, Silke and Huang, Jingjing and Messens, Joris and Van Breusegem, Frank},
  issn         = {0022-0957},
  journal      = {JOURNAL OF EXPERIMENTAL BOTANY},
  keyword      = {NADPH OXIDASE,NITRIC-OXIDE,MAP KINASE,REDOX REGULATION,HYDROGEN-PEROXIDE,ARABIDOPSIS-THALIANA,OSMPK6 IN-VITRO,ABSCISIC-ACID,ANION CHANNEL SLAH3,ACTIVATED PROTEIN-KINASE,signal perception,reactive oxygen species,redox regulation,phytohormone signalling,oxidative stress,Cysteine oxidative post-translational modifications},
  language     = {eng},
  number       = {10},
  pages        = {2923--2934},
  title        = {Oxidative post-translational modifications of cysteine residues in plant signal transduction},
  url          = {http://dx.doi.org/10.1093/jxb/erv084},
  volume       = {66},
  year         = {2015},
}

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