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Transforming growth factor-beta 1 pathways in inflammatory airway diseases

(2014) ALLERGY. 69(6). p.699-707
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Abstract
Transforming growth factor-beta 1 (TGF-1) has been reported being involved in the remodeling and immunosuppression processes of inflammatory airway diseases; understanding the regulation of TGF-1 is therefore a key to unravel the pathomechanisms of these diseases. This review briefly summarizes the current knowledge on the influencing factors for driving TGF-1 and its regulatory pathways in inflammatory airway diseases and discusses possible therapeutic approaches to TGF-1 control. The factors include smoking and oxidative stress, prostaglandins (PGs), leukotrienes (LTs), bradykinin (BK), and microRNAs (miRs). Based on the summary, new innovative treatment strategies may be developed for inflammatory airway diseases with an impaired expression of TGF-1.
Keywords
influencing factors, airway diseases, oxidative stress, smoking, transforming growth factor-beta, OBSTRUCTIVE PULMONARY-DISEASE, PARANASAL SINUS DISEASE, TGF-BETA, CHRONIC RHINOSINUSITIS, OXIDATIVE STRESS, CIGARETTE-SMOKE, NASAL POLYPOSIS, MITOCHONDRIAL DYSFUNCTION, RECEPTOR ANTAGONIST, CELL PROLIFERATION

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Citation

Please use this url to cite or link to this publication:

MLA
Yang, Y et al. “Transforming Growth Factor-beta 1 Pathways in Inflammatory Airway Diseases.” ALLERGY 69.6 (2014): 699–707. Print.
APA
Yang, Y, Zhang, N., Lan, F., Van Crombruggen, K., Fang, L., Hu, G., Hong, S., et al. (2014). Transforming growth factor-beta 1 pathways in inflammatory airway diseases. ALLERGY, 69(6), 699–707.
Chicago author-date
Yang, Y, Nan Zhang, F Lan, Koen Van Crombruggen, L Fang, G Hu, S Hong, and Claus Bachert. 2014. “Transforming Growth Factor-beta 1 Pathways in Inflammatory Airway Diseases.” Allergy 69 (6): 699–707.
Chicago author-date (all authors)
Yang, Y, Nan Zhang, F Lan, Koen Van Crombruggen, L Fang, G Hu, S Hong, and Claus Bachert. 2014. “Transforming Growth Factor-beta 1 Pathways in Inflammatory Airway Diseases.” Allergy 69 (6): 699–707.
Vancouver
1.
Yang Y, Zhang N, Lan F, Van Crombruggen K, Fang L, Hu G, et al. Transforming growth factor-beta 1 pathways in inflammatory airway diseases. ALLERGY. 2014;69(6):699–707.
IEEE
[1]
Y. Yang et al., “Transforming growth factor-beta 1 pathways in inflammatory airway diseases,” ALLERGY, vol. 69, no. 6, pp. 699–707, 2014.
@article{6863527,
  abstract     = {Transforming growth factor-beta 1 (TGF-1) has been reported being involved in the remodeling and immunosuppression processes of inflammatory airway diseases; understanding the regulation of TGF-1 is therefore a key to unravel the pathomechanisms of these diseases. This review briefly summarizes the current knowledge on the influencing factors for driving TGF-1 and its regulatory pathways in inflammatory airway diseases and discusses possible therapeutic approaches to TGF-1 control. The factors include smoking and oxidative stress, prostaglandins (PGs), leukotrienes (LTs), bradykinin (BK), and microRNAs (miRs). Based on the summary, new innovative treatment strategies may be developed for inflammatory airway diseases with an impaired expression of TGF-1.},
  author       = {Yang, Y and Zhang, Nan and Lan, F and Van Crombruggen, Koen and Fang, L and Hu, G and Hong, S and Bachert, Claus},
  issn         = {0105-4538},
  journal      = {ALLERGY},
  keywords     = {influencing factors,airway diseases,oxidative stress,smoking,transforming growth factor-beta,OBSTRUCTIVE PULMONARY-DISEASE,PARANASAL SINUS DISEASE,TGF-BETA,CHRONIC RHINOSINUSITIS,OXIDATIVE STRESS,CIGARETTE-SMOKE,NASAL POLYPOSIS,MITOCHONDRIAL DYSFUNCTION,RECEPTOR ANTAGONIST,CELL PROLIFERATION},
  language     = {eng},
  number       = {6},
  pages        = {699--707},
  title        = {Transforming growth factor-beta 1 pathways in inflammatory airway diseases},
  url          = {http://dx.doi.org/10.1111/all.12403},
  volume       = {69},
  year         = {2014},
}

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