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Factors influencing the process of medication (non-)adherence and (non-)persistence in breast cancer patients with adjuvant antihormonal therapy : a qualitative study

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Abstract
Non-adherence and non-persistence in breast cancer patients taking antihormonal therapy (AHT) is common. However, the complex patterns and dynamics of adherence and persistence are still not fully understood. This study aims to give insight into the process of (non-)adherence and (non-)persistence by researching influencing factors and their interrelatedness in breast cancer patients taking AHT by means of a qualitative study with semi-structured interviews. The sample consisted of 31 breast cancer patients treated with AHT. Purposive and theoretical sampling and the constant comparison method based on a grounded theory approach were used. Expectations regarding the impact of AHT, social support from family and friends, and recognition from healthcare professionals were found to influence the process of non-adherence and non-persistence. The results of this study can help healthcare professionals understand why breast cancer patients taking AHT do not always adhere to or persist in taking the therapy and may facilitate patient-tailored interventions.
Keywords
antihormonal therapy, adherence, persistence, qualitative study, influencing factors, process, ADHERENCE, TAMOXIFEN, PERSISTENCE, WOMEN, DISCONTINUATION, PURPOSEFUL, CARE

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MLA
Verbrugghe, Mathieu et al. “Factors Influencing the Process of Medication (non-)adherence and (non-)persistence in Breast Cancer Patients with Adjuvant Antihormonal Therapy : a Qualitative Study.” EUROPEAN JOURNAL OF CANCER CARE 26.2 (2017): n. pag. Print.
APA
Verbrugghe, M., Verhaeghe, S., Decoene, E., De Baere, S., Vandendorpe, B., & Van Hecke, A. (2017). Factors influencing the process of medication (non-)adherence and (non-)persistence in breast cancer patients with adjuvant antihormonal therapy : a qualitative study. EUROPEAN JOURNAL OF CANCER CARE, 26(2).
Chicago author-date
Verbrugghe, Mathieu, Sofie Verhaeghe, Elsie Decoene, Sophia De Baere, Babette Vandendorpe, and Ann Van Hecke. 2017. “Factors Influencing the Process of Medication (non-)adherence and (non-)persistence in Breast Cancer Patients with Adjuvant Antihormonal Therapy : a Qualitative Study.” European Journal of Cancer Care 26 (2).
Chicago author-date (all authors)
Verbrugghe, Mathieu, Sofie Verhaeghe, Elsie Decoene, Sophia De Baere, Babette Vandendorpe, and Ann Van Hecke. 2017. “Factors Influencing the Process of Medication (non-)adherence and (non-)persistence in Breast Cancer Patients with Adjuvant Antihormonal Therapy : a Qualitative Study.” European Journal of Cancer Care 26 (2).
Vancouver
1.
Verbrugghe M, Verhaeghe S, Decoene E, De Baere S, Vandendorpe B, Van Hecke A. Factors influencing the process of medication (non-)adherence and (non-)persistence in breast cancer patients with adjuvant antihormonal therapy : a qualitative study. EUROPEAN JOURNAL OF CANCER CARE. 2017;26(2).
IEEE
[1]
M. Verbrugghe, S. Verhaeghe, E. Decoene, S. De Baere, B. Vandendorpe, and A. Van Hecke, “Factors influencing the process of medication (non-)adherence and (non-)persistence in breast cancer patients with adjuvant antihormonal therapy : a qualitative study,” EUROPEAN JOURNAL OF CANCER CARE, vol. 26, no. 2, 2017.
@article{6862045,
  abstract     = {Non-adherence and non-persistence in breast cancer patients taking antihormonal therapy (AHT) is common. However, the complex patterns and dynamics of adherence and persistence are still not fully understood. This study aims to give insight into the process of (non-)adherence and (non-)persistence by researching influencing factors and their interrelatedness in breast cancer patients taking AHT by means of a qualitative study with semi-structured interviews. The sample consisted of 31 breast cancer patients treated with AHT. Purposive and theoretical sampling and the constant comparison method based on a grounded theory approach were used. Expectations regarding the impact of AHT, social support from family and friends, and recognition from healthcare professionals were found to influence the process of non-adherence and non-persistence. The results of this study can help healthcare professionals understand why breast cancer patients taking AHT do not always adhere to or persist in taking the therapy and may facilitate patient-tailored interventions.},
  articleno    = {e12339},
  author       = {Verbrugghe, Mathieu and Verhaeghe, Sofie and Decoene, Elsie and De Baere, Sophia and Vandendorpe, Babette and Van Hecke, Ann},
  issn         = {0961-5423},
  journal      = {EUROPEAN JOURNAL OF CANCER CARE},
  keywords     = {antihormonal therapy,adherence,persistence,qualitative study,influencing factors,process,ADHERENCE,TAMOXIFEN,PERSISTENCE,WOMEN,DISCONTINUATION,PURPOSEFUL,CARE},
  language     = {eng},
  number       = {2},
  pages        = {11},
  title        = {Factors influencing the process of medication (non-)adherence and (non-)persistence in breast cancer patients with adjuvant antihormonal therapy : a qualitative study},
  url          = {http://dx.doi.org/10.1111/ecc.12339},
  volume       = {26},
  year         = {2017},
}

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