@article{6847834,
  abstract     = {Case Presentation : We describe a case of a patient who presents with jaundice, elevated cholestatic liver enzymes, an extreme weight loss and a midcholedochal stricture very suspect for a -cholangiocarcinoma. In the conviction of malignancy, although the absence of anatomopathological prove, the patient underwent a choledochal resection. The anatomopathological specimen revealed no malignancy. In the year following resection, the patient keeps presenting with bile duct strictures and further weight loss. -Ultimately the diagnosis of Ig G4-related cholangitis is withheld. Therapy with corticosteroids is initiated with a spectacular clinical, biochemical and radiographical result. 
Discussion : IgG4-related cholangitis is the biliary presentation of IgG4-related disease, a recently discovered entity of fibroinflammatory masses which can affect virtually every organ in the body. It is characterized by a dense lymphoplasmacytic infiltrate, storiform fibrosis, obliterative phlebitis and a presence of >30 IgG4-positive plasma cells per high power field. Main differential -diagnosis contains cholangiocarcinoma and primary sclerosing cholan-gitis. Corticoids are cornerstone of therapy, with azathioprine frequently used as a maintenance in case of relapse. 
Conclusion : With this case we want to draw the attention to a rather uncommon cause of biliary obstruction, easily mistaken for a cholangiocarcinoma.},
  author       = {De Both, Anneleen and Van Vlierberghe, Hans and Geerts, Anja and Libbrecht, Louis and Verhelst, Xavier},
  issn         = {0001-5644},
  journal      = {ACTA GASTRO-ENTEROLOGICA BELGICA},
  keywords     = {IgG4-related disease,IgG4-related cholangitis,biliary obstruction,IMMUNOGLOBULIN G4-ASSOCIATED CHOLANGITIS,G4-RELATED SCLEROSING CHOLANGITIS,CLINICOPATHOLOGICAL-ENTITY,DISEASE,CHOLANGIOCARCINOMA,PANCREATITIS},
  language     = {eng},
  number       = {1},
  pages        = {62--64},
  title        = {IgG4-related cholangitis : case report and literature review},
  volume       = {78},
  year         = {2015},
}

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