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Production and enrichment of bioactive peptides derived from milk proteins

Lieselot Vercruysse (UGent) , John Van Camp (UGent) , Koen Dewettinck (UGent) and Guy Smagghe (UGent)
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Abstract
In this chapter, information is given on the production of bioactive peptides from milk proteins. After defining bioactive peptides, the necessity to release bioactive peptides from the parent protein is discussed. Then, the two main approaches for release, namely enzymatic hydrolysis and microbial fermentation are reviewed. Next, an overview is given of the main unit operations that can be applied for the enrichment and selective isolation of bioactive peptides from the protein hydrolysates, including membrane filtration, chromatography and precipitation. Attention is given mainly to ACE-inhibitory peptides, and to processes that show potential for application in the dairy industry.
Keywords
milk, bioactive peptides, enzymatic hydrolysis, microbial fermentation, enrichment

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MLA
Vercruysse, Lieselot, et al. “Production and Enrichment of Bioactive Peptides Derived from Milk Proteins.” Dairy-Derived Ingredients : Food and Nutraceutical Uses, edited by Milena Corredig, vol. 3, CRC Press, 2009, pp. 51–67, doi:10.1533/9781845697198.1.51.
APA
Vercruysse, L., Van Camp, J., Dewettinck, K., & Smagghe, G. (2009). Production and enrichment of bioactive peptides derived from milk proteins. In M. Corredig (Ed.), Dairy-derived ingredients : food and nutraceutical uses (Vol. 3, pp. 51–67). CRC Press. https://doi.org/10.1533/9781845697198.1.51
Chicago author-date
Vercruysse, Lieselot, John Van Camp, Koen Dewettinck, and Guy Smagghe. 2009. “Production and Enrichment of Bioactive Peptides Derived from Milk Proteins.” In Dairy-Derived Ingredients : Food and Nutraceutical Uses, edited by Milena Corredig, 3:51–67. CRC Press. https://doi.org/10.1533/9781845697198.1.51.
Chicago author-date (all authors)
Vercruysse, Lieselot, John Van Camp, Koen Dewettinck, and Guy Smagghe. 2009. “Production and Enrichment of Bioactive Peptides Derived from Milk Proteins.” In Dairy-Derived Ingredients : Food and Nutraceutical Uses, ed by. Milena Corredig, 3:51–67. CRC Press. doi:10.1533/9781845697198.1.51.
Vancouver
1.
Vercruysse L, Van Camp J, Dewettinck K, Smagghe G. Production and enrichment of bioactive peptides derived from milk proteins. In: Corredig M, editor. Dairy-derived ingredients : food and nutraceutical uses. CRC Press; 2009. p. 51–67.
IEEE
[1]
L. Vercruysse, J. Van Camp, K. Dewettinck, and G. Smagghe, “Production and enrichment of bioactive peptides derived from milk proteins,” in Dairy-derived ingredients : food and nutraceutical uses, vol. 3, M. Corredig, Ed. CRC Press, 2009, pp. 51–67.
@incollection{681551,
  abstract     = {{In this chapter, information is given on the production of bioactive peptides from milk proteins. After defining bioactive peptides, the necessity to release bioactive peptides from the parent protein is discussed. Then, the two main approaches for release, namely enzymatic hydrolysis and microbial fermentation are reviewed. Next, an overview is given of the main unit operations that can be applied for the enrichment and selective isolation of bioactive peptides from the protein hydrolysates, including membrane filtration, chromatography and precipitation. Attention is given mainly to ACE-inhibitory peptides, and to processes that show potential for application in the dairy industry.}},
  author       = {{Vercruysse, Lieselot and Van Camp, John and Dewettinck, Koen and Smagghe, Guy}},
  booktitle    = {{Dairy-derived ingredients : food and nutraceutical uses}},
  editor       = {{Corredig, Milena}},
  isbn         = {{1439820708}},
  keywords     = {{milk,bioactive peptides,enzymatic hydrolysis,microbial fermentation,enrichment}},
  language     = {{eng}},
  pages        = {{51--67}},
  publisher    = {{CRC Press}},
  series       = {{Production of bioactive peptides}},
  title        = {{Production and enrichment of bioactive peptides derived from milk proteins}},
  url          = {{http://dx.doi.org/10.1533/9781845697198.1.51}},
  volume       = {{3}},
  year         = {{2009}},
}

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