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Cardiovascular risk assessment through target organ damage: role of carotid to femoral pulse wave velocity

Pierre Boutouyrie, SEBASTIAN VERMEERSCH UGent, Stéphane Laurent and Marie Briet (2008) CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. 35(4). p.530-533
abstract
1. Cardiovascular risk prediction relies on classical risk factors such as age, gender, lipids, hypertension, smoking and diabetes. Although the value of such scales of risk is high for populations, its value for individuals is reduced and much influenced by non-modifiable risk factors (age and sex). 2. Biomarkers of risk have been deceiving and the genome-wide scan approach is too recent to have been useful. Target-organ damage may help in selecting patients at high risk and determine the necessity of intervention. 3. Aortic pulse wave velocity, an index of aortic stiffness, has been widely validated as providing additional risk prediction above and beyond classical risk factors and has now entered the 2007 guidelines for hypertension of the European Society of Hypertension. 4. We aim to show that individual prediction of cardiovascular-related death can be improved by taking aortic stiffness into account in a cohort of patients during a longitudinal follow-up. 5. Points to be improved are the homogenization and spreading of the technique of measurement, the establishment of a reference value database and the demonstration of the added value of aortic stiffness screening and stratification in interventional trials.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (proceedingsPaper)
publication status
published
subject
keyword
cardiovascular risk, epidemiology, aorta, artery, mortality, stiffness, CORONARY-HEART-DISEASE, INDEPENDENT PREDICTOR, HYPERTENSIVE PATIENTS, CONSENSUS DOCUMENT, ARTERIAL STIFFNESS, AORTIC STIFFNESS, PRESSURE, EVENTS
journal title
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Clin. Exp. Pharmacol. Physiol.
volume
35
issue
4
pages
530 - 533
publisher
Blackwell
place of publication
Oxford, UK
conference name
4th Franco-Australian Meeting on Hypertension
conference location
Kakadu National Park, Australia
conference start
2007-09-09
conference end
2007-09-12
Web of Science type
Proceedings Paper
Web of Science id
000254296600037
JCR category
PHYSIOLOGY
JCR impact factor
2.196 (2008)
JCR rank
38/73 (2008)
JCR quartile
3 (2008)
ISSN
0305-1870
DOI
10.1111/j.1440-1681.2008.04911.x
language
English
UGent publication?
no
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
677282
handle
http://hdl.handle.net/1854/LU-677282
date created
2009-06-04 10:56:48
date last changed
2009-07-02 13:59:48
@article{677282,
  abstract     = {1. Cardiovascular risk prediction relies on classical risk factors such as age, gender, lipids, hypertension, smoking and diabetes. Although the value of such scales of risk is high for populations, its value for individuals is reduced and much influenced by non-modifiable risk factors (age and sex).
2. Biomarkers of risk have been deceiving and the genome-wide scan approach is too recent to have been useful. Target-organ damage may help in selecting patients at high risk and determine the necessity of intervention.
3. Aortic pulse wave velocity, an index of aortic stiffness, has been widely validated as providing additional risk prediction above and beyond classical risk factors and has now entered the 2007 guidelines for hypertension of the European Society of Hypertension.
4. We aim to show that individual prediction of cardiovascular-related death can be improved by taking aortic stiffness into account in a cohort of patients during a longitudinal follow-up.
5. Points to be improved are the homogenization and spreading of the technique of measurement, the establishment of a reference value database and the demonstration of the added value of aortic stiffness screening and stratification in interventional trials.},
  author       = {Boutouyrie, Pierre and VERMEERSCH, SEBASTIAN and Laurent, St{\'e}phane and Briet, Marie},
  issn         = {0305-1870},
  journal      = {CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY},
  keyword      = {cardiovascular risk,epidemiology,aorta,artery,mortality,stiffness,CORONARY-HEART-DISEASE,INDEPENDENT PREDICTOR,HYPERTENSIVE PATIENTS,CONSENSUS DOCUMENT,ARTERIAL STIFFNESS,AORTIC STIFFNESS,PRESSURE,EVENTS},
  language     = {eng},
  location     = {Kakadu National Park, Australia},
  number       = {4},
  pages        = {530--533},
  publisher    = {Blackwell},
  title        = {Cardiovascular risk assessment through target organ damage: role of carotid to femoral pulse wave velocity},
  url          = {http://dx.doi.org/10.1111/j.1440-1681.2008.04911.x},
  volume       = {35},
  year         = {2008},
}

Chicago
Boutouyrie, Pierre, SEBASTIAN VERMEERSCH, Stéphane Laurent, and Marie Briet. 2008. “Cardiovascular Risk Assessment Through Target Organ Damage: Role of Carotid to Femoral Pulse Wave Velocity.” Clinical and Experimental Pharmacology and Physiology 35 (4): 530–533.
APA
Boutouyrie, P., VERMEERSCH, S., Laurent, S., & Briet, M. (2008). Cardiovascular risk assessment through target organ damage: role of carotid to femoral pulse wave velocity. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 35(4), 530–533. Presented at the 4th Franco-Australian Meeting on Hypertension.
Vancouver
1.
Boutouyrie P, VERMEERSCH S, Laurent S, Briet M. Cardiovascular risk assessment through target organ damage: role of carotid to femoral pulse wave velocity. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. Oxford, UK: Blackwell; 2008;35(4):530–3.
MLA
Boutouyrie, Pierre, SEBASTIAN VERMEERSCH, Stéphane Laurent, et al. “Cardiovascular Risk Assessment Through Target Organ Damage: Role of Carotid to Femoral Pulse Wave Velocity.” CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 35.4 (2008): 530–533. Print.