Ghent University Academic Bibliography

Advanced

Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems

Karolien De Bosscher UGent, Kathleen Van Craenenbroeck UGent, Onno C. Meijer and Guy Haegeman UGent (2008) EUROPEAN JOURNAL OF PHARMACOLOGY. 583(2-3). p.290-302
abstract
Glucocorticoids control immune homeostasis and regulate stress responses in the human body to a large extent via the glucocorticoid receptor. This transcription factor can modulate gene expression either through direct DNA binding (mainly resulting in transactivation) or independent of DNA binding (in the majority of cases resulting in transrepression). The aim of this review is to discuss the mechanistic basis and applicability of different glucocorticoid receptor modulators in various affections, ranging from immune disorders to mental dysfunctions. (C) 2008 Elsevier B.V. All rights reserved.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
NUCLEAR RECEPTORS, GENE-EXPRESSION, RESPONSE ELEMENT-BINDING, PROTEIN-PROTEIN-INTERACTION, CORTICOTROPIN-RELEASING HORMONE, CORTICOSTEROID-BINDING GLOBULIN, NF-KAPPA-B, NF-kappa B, inflammation, HPA, stress, glucocorticoid receptor, transrepression, DNA-BINDING, MINERALOCORTICOID RECEPTORS, MAJOR DEPRESSION
journal title
EUROPEAN JOURNAL OF PHARMACOLOGY
Eur. J. Pharmacol.
volume
583
issue
2-3
pages
290 - 302
publisher
Elsevier Science
place of publication
AMSTERDAM, NETHERLANDS
Web of Science type
Review
Web of Science id
000254923600012
JCR category
PHARMACOLOGY & PHARMACY
JCR impact factor
2.787 (2008)
JCR rank
79/216 (2008)
JCR quartile
2 (2008)
ISSN
0014-2999
DOI
10.1016/j.ejphar.2007.11.076
language
English
UGent publication?
yes
classification
A1
id
671483
handle
http://hdl.handle.net/1854/LU-671483
date created
2009-05-29 10:23:48
date last changed
2009-06-04 09:50:19
@article{671483,
  abstract     = {Glucocorticoids control immune homeostasis and regulate stress responses in the human body to a large extent via the glucocorticoid receptor. This transcription factor can modulate gene expression either through direct DNA binding (mainly resulting in transactivation) or independent of DNA binding (in the majority of cases resulting in transrepression). The aim of this review is to discuss the mechanistic basis and applicability of different glucocorticoid receptor modulators in various affections, ranging from immune disorders to mental dysfunctions. (C) 2008 Elsevier B.V. All rights reserved.},
  author       = {De Bosscher, Karolien and Van Craenenbroeck, Kathleen and Meijer, Onno C. and Haegeman, Guy},
  issn         = {0014-2999},
  journal      = {EUROPEAN JOURNAL OF PHARMACOLOGY},
  keyword      = {NUCLEAR RECEPTORS,GENE-EXPRESSION,RESPONSE ELEMENT-BINDING,PROTEIN-PROTEIN-INTERACTION,CORTICOTROPIN-RELEASING HORMONE,CORTICOSTEROID-BINDING GLOBULIN,NF-KAPPA-B,NF-kappa B,inflammation,HPA,stress,glucocorticoid receptor,transrepression,DNA-BINDING,MINERALOCORTICOID RECEPTORS,MAJOR DEPRESSION},
  language     = {eng},
  number       = {2-3},
  pages        = {290--302},
  publisher    = {Elsevier Science},
  title        = {Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems},
  url          = {http://dx.doi.org/10.1016/j.ejphar.2007.11.076},
  volume       = {583},
  year         = {2008},
}

Chicago
De Bosscher, Karolien, Kathleen Van Craenenbroeck, Onno C. Meijer, and Guy Haegeman. 2008. “Selective Transrepression Versus Transactivation Mechanisms by Glucocorticoid Receptor Modulators in Stress and Immune Systems.” European Journal of Pharmacology 583 (2-3): 290–302.
APA
De Bosscher, K., Van Craenenbroeck, K., Meijer, O. C., & Haegeman, G. (2008). Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems. EUROPEAN JOURNAL OF PHARMACOLOGY, 583(2-3), 290–302.
Vancouver
1.
De Bosscher K, Van Craenenbroeck K, Meijer OC, Haegeman G. Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems. EUROPEAN JOURNAL OF PHARMACOLOGY. AMSTERDAM, NETHERLANDS: Elsevier Science; 2008;583(2-3):290–302.
MLA
De Bosscher, Karolien, Kathleen Van Craenenbroeck, Onno C. Meijer, et al. “Selective Transrepression Versus Transactivation Mechanisms by Glucocorticoid Receptor Modulators in Stress and Immune Systems.” EUROPEAN JOURNAL OF PHARMACOLOGY 583.2-3 (2008): 290–302. Print.