Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria
- Author
- Davy Sinnaeve (UGent) , Catherine Michaux, Johan Van Hemel, Jan Vandenkerckhove, Eric Peys, Frans Borremans (UGent) , Benedikt Sas (UGent) , Johan Wouters and José Martins (UGent)
- Organization
- Abstract
- Two new cyclic lipodepsipeptides named pseudodesmin A and B have been isolated from Pseudomonas bacteria collected from the mucus layer in the skin of the black belly salamander. Both compounds show moderate antibacterial activity against Gram positive bacteria, including MRSA. Complete 1H, 13C and 15N NMR assignment of both compounds afforded their covalent structure and served to guide the analysis of LC-MS and X-ray diffraction data from which the final stereochemistry could be established. Both molecules can be categorized as new members of the viscosin group of cyclic lipodepsipeptides.
- Keywords
- pseudodesmin, Pseudomonas, Plethodontidae, X-ray structure, NMR, lipodepsipeptide, viscosin group, CRYSTAL-STRUCTURES, FLUORESCENS DR54, PSEUDOPHOMIN-B, REACTANS, STRAIN, BIOSURFACTANT, REFINEMENT, VISCOSIN, WLIP, MODEL
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-598780
- MLA
- Sinnaeve, Davy, et al. “Structure and X-Ray Conformation of Pseudodesmins A and B, Two New Cyclic Lipodepsipeptides from Pseudomonas Bacteria.” TETRAHEDRON, vol. 65, no. 21, 2009, pp. 4173–81, doi:10.1016/j.tet.2009.03.045.
- APA
- Sinnaeve, D., Michaux, C., Van Hemel, J., Vandenkerckhove, J., Peys, E., Borremans, F., … Martins, J. (2009). Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria. TETRAHEDRON, 65(21), 4173–4181. https://doi.org/10.1016/j.tet.2009.03.045
- Chicago author-date
- Sinnaeve, Davy, Catherine Michaux, Johan Van Hemel, Jan Vandenkerckhove, Eric Peys, Frans Borremans, Benedikt Sas, Johan Wouters, and José Martins. 2009. “Structure and X-Ray Conformation of Pseudodesmins A and B, Two New Cyclic Lipodepsipeptides from Pseudomonas Bacteria.” TETRAHEDRON 65 (21): 4173–81. https://doi.org/10.1016/j.tet.2009.03.045.
- Chicago author-date (all authors)
- Sinnaeve, Davy, Catherine Michaux, Johan Van Hemel, Jan Vandenkerckhove, Eric Peys, Frans Borremans, Benedikt Sas, Johan Wouters, and José Martins. 2009. “Structure and X-Ray Conformation of Pseudodesmins A and B, Two New Cyclic Lipodepsipeptides from Pseudomonas Bacteria.” TETRAHEDRON 65 (21): 4173–4181. doi:10.1016/j.tet.2009.03.045.
- Vancouver
- 1.Sinnaeve D, Michaux C, Van Hemel J, Vandenkerckhove J, Peys E, Borremans F, et al. Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria. TETRAHEDRON. 2009;65(21):4173–81.
- IEEE
- [1]D. Sinnaeve et al., “Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria,” TETRAHEDRON, vol. 65, no. 21, pp. 4173–4181, 2009.
@article{598780, abstract = {{Two new cyclic lipodepsipeptides named pseudodesmin A and B have been isolated from Pseudomonas bacteria collected from the mucus layer in the skin of the black belly salamander. Both compounds show moderate antibacterial activity against Gram positive bacteria, including MRSA. Complete 1H, 13C and 15N NMR assignment of both compounds afforded their covalent structure and served to guide the analysis of LC-MS and X-ray diffraction data from which the final stereochemistry could be established. Both molecules can be categorized as new members of the viscosin group of cyclic lipodepsipeptides.}}, author = {{Sinnaeve, Davy and Michaux, Catherine and Van Hemel, Johan and Vandenkerckhove, Jan and Peys, Eric and Borremans, Frans and Sas, Benedikt and Wouters, Johan and Martins, José}}, issn = {{0040-4020}}, journal = {{TETRAHEDRON}}, keywords = {{pseudodesmin,Pseudomonas,Plethodontidae,X-ray structure,NMR,lipodepsipeptide,viscosin group,CRYSTAL-STRUCTURES,FLUORESCENS DR54,PSEUDOPHOMIN-B,REACTANS,STRAIN,BIOSURFACTANT,REFINEMENT,VISCOSIN,WLIP,MODEL}}, language = {{eng}}, number = {{21}}, pages = {{4173--4181}}, title = {{Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria}}, url = {{http://doi.org/10.1016/j.tet.2009.03.045}}, volume = {{65}}, year = {{2009}}, }
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