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Anaphylaxis after intravenous administration of amoxicillin/clavulanic acid in two dogs under general anesthesia

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Abstract
In this case series, the occurrence and successful treatment of anaphylaxis after the intravenous administration of amoxicillin/clavulanic acid are described in two dogs under general anesthesia. Within five to ten minutes after the administration of the antibiotic, a severe hypotension occurred in both dogs, accompanied by labial and periorbital swelling and erythema. Therapy consisted of counteracting the cardiovascular effects of anaphylaxis and preventing further release of inflammatory mediators. Both dogs recovered uneventfully from the drug-related anaphylaxis.
Keywords
DRUG-INDUCED ANAPHYLAXIS, WORLD-ALLERGY-ORGANIZATION, HYPERSENSITIVITY REACTIONS, EPINEPHRINE

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Citation

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MLA
Bosmans, Tim, et al. “Anaphylaxis after Intravenous Administration of Amoxicillin/Clavulanic Acid in Two Dogs under General Anesthesia.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, vol. 83, no. 1, 2014, pp. 14–19.
APA
Bosmans, T., Melis, S., De Rooster, H., Van Goethem, B., Defauw, P., Van Soens, I., & Polis, I. (2014). Anaphylaxis after intravenous administration of amoxicillin/clavulanic acid in two dogs under general anesthesia. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, 83(1), 14–19.
Chicago author-date
Bosmans, Tim, Sanne Melis, Hilde De Rooster, Bart Van Goethem, Pieter Defauw, Iris Van Soens, and Ingeborgh Polis. 2014. “Anaphylaxis after Intravenous Administration of Amoxicillin/Clavulanic Acid in Two Dogs under General Anesthesia.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 83 (1): 14–19.
Chicago author-date (all authors)
Bosmans, Tim, Sanne Melis, Hilde De Rooster, Bart Van Goethem, Pieter Defauw, Iris Van Soens, and Ingeborgh Polis. 2014. “Anaphylaxis after Intravenous Administration of Amoxicillin/Clavulanic Acid in Two Dogs under General Anesthesia.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 83 (1): 14–19.
Vancouver
1.
Bosmans T, Melis S, De Rooster H, Van Goethem B, Defauw P, Van Soens I, et al. Anaphylaxis after intravenous administration of amoxicillin/clavulanic acid in two dogs under general anesthesia. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT. 2014;83(1):14–9.
IEEE
[1]
T. Bosmans et al., “Anaphylaxis after intravenous administration of amoxicillin/clavulanic acid in two dogs under general anesthesia,” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, vol. 83, no. 1, pp. 14–19, 2014.
@article{5984287,
  abstract     = {{In this case series, the occurrence and successful treatment of anaphylaxis after the intravenous administration of amoxicillin/clavulanic acid are described in two dogs under general anesthesia. Within five to ten minutes after the administration of the antibiotic, a severe hypotension occurred in both dogs, accompanied by labial and periorbital swelling and erythema. Therapy consisted of counteracting the cardiovascular effects of anaphylaxis and preventing further release of inflammatory mediators. Both dogs recovered uneventfully from the drug-related anaphylaxis.}},
  author       = {{Bosmans, Tim and Melis, Sanne and De Rooster, Hilde and Van Goethem, Bart and Defauw, Pieter and Van Soens, Iris and Polis, Ingeborgh}},
  issn         = {{0303-9021}},
  journal      = {{VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT}},
  keywords     = {{DRUG-INDUCED ANAPHYLAXIS,WORLD-ALLERGY-ORGANIZATION,HYPERSENSITIVITY REACTIONS,EPINEPHRINE}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{14--19}},
  title        = {{Anaphylaxis after intravenous administration of amoxicillin/clavulanic acid in two dogs under general anesthesia}},
  url          = {{http://vdt.ugent.be/sites/default/files/artikel02.pdf}},
  volume       = {{83}},
  year         = {{2014}},
}

Web of Science
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