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Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines

(2014) SYNLETT. 25(1). p.75-80
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Abstract
The synthetic utility of 3-bromo-3-ethylazetidines has been demonstrated by the straightforward preparation of 3-alkoxy-, 3-aryloxy-, 3-acetoxy-, 3-hydroxy-, 3-cyano-, 3-carbamoyl- and 3-amino-3-ethylazetidines. In addition, 3-bromo-3-ethylazetidines have been successfully deployed as precursors for a convenient synthesis of 3-ethylideneazetidines, which served as starting materials for the preparation of novel functionalized azetidines and spirocyclic azetidine building blocks.
Keywords
ring opening, rearrangement, spiro compounds, STEREOSELECTIVE-SYNTHESIS, CONVENIENT SYNTHESIS, BUILDING-BLOCKS, POLYOXIMIC ACID, BETA-LACTAMS, AZIRIDINES, DERIVATIVES, REACTIVITY, 2-METHYLENEAZETIDINES, TRANSFORMATIONS, nucleophiles, nitrogen, heterocycles

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Citation

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MLA
Stanković, Sonja et al. “Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the Synthesis of Functionalized Azetidines.” SYNLETT 25.1 (2014): 75–80. Print.
APA
Stanković, Sonja, D’hooghe, M., Vanderhaegen, T., Abbaspour Tehrani, K., & De Kimpe, N. (2014). Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines. SYNLETT, 25(1), 75–80.
Chicago author-date
Stanković, Sonja, Matthias D’hooghe, Tim Vanderhaegen, Kourosh Abbaspour Tehrani, and Norbert De Kimpe. 2014. “Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the Synthesis of Functionalized Azetidines.” Synlett 25 (1): 75–80.
Chicago author-date (all authors)
Stanković, Sonja, Matthias D’hooghe, Tim Vanderhaegen, Kourosh Abbaspour Tehrani, and Norbert De Kimpe. 2014. “Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the Synthesis of Functionalized Azetidines.” Synlett 25 (1): 75–80.
Vancouver
1.
Stanković S, D’hooghe M, Vanderhaegen T, Abbaspour Tehrani K, De Kimpe N. Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines. SYNLETT. 2014;25(1):75–80.
IEEE
[1]
S. Stanković, M. D’hooghe, T. Vanderhaegen, K. Abbaspour Tehrani, and N. De Kimpe, “Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines,” SYNLETT, vol. 25, no. 1, pp. 75–80, 2014.
@article{5946312,
  abstract     = {The synthetic utility of 3-bromo-3-ethylazetidines has been demonstrated by the straightforward preparation of 3-alkoxy-, 3-aryloxy-, 3-acetoxy-, 3-hydroxy-, 3-cyano-, 3-carbamoyl- and 3-amino-3-ethylazetidines. In addition, 3-bromo-3-ethylazetidines have been successfully deployed as precursors for a convenient synthesis of 3-ethylideneazetidines, which served as starting materials for the preparation of novel functionalized azetidines and spirocyclic azetidine building blocks.},
  author       = {Stanković, Sonja and D'hooghe, Matthias and Vanderhaegen, Tim and Abbaspour Tehrani, Kourosh and De Kimpe, Norbert},
  issn         = {0936-5214},
  journal      = {SYNLETT},
  keywords     = {ring opening,rearrangement,spiro compounds,STEREOSELECTIVE-SYNTHESIS,CONVENIENT SYNTHESIS,BUILDING-BLOCKS,POLYOXIMIC ACID,BETA-LACTAMS,AZIRIDINES,DERIVATIVES,REACTIVITY,2-METHYLENEAZETIDINES,TRANSFORMATIONS,nucleophiles,nitrogen,heterocycles},
  language     = {eng},
  number       = {1},
  pages        = {75--80},
  title        = {Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines},
  url          = {http://dx.doi.org/10.1055/s-0033-1340250},
  volume       = {25},
  year         = {2014},
}

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